22 items (Aspergillus ibericus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Your Input:
	A0A395HFD5	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1413 aa)
	A0A395GI96	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (120 aa)
	A0A395GL68	Uncharacterized protein. (703 aa)
	A0A395GNL1	Prefoldin subunit 5. (171 aa)
	A0A395GPA8	Sporulation protein. (240 aa)
	A0A395GPR1	Uncharacterized protein. (202 aa)
	A0A395GRJ0	Proteasome regulatory particle subunit Rpt6; Belongs to the AAA ATPase family. (389 aa)
	A0A395GSG3	26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. (393 aa)
	A0A395GSR2	Uncharacterized protein. (666 aa)
	A0A395GVY6	CDC73-domain-containing protein. (473 aa)
	A0A395GX73	Kinase-like protein. (337 aa)
	A0A395GZW9	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (755 aa)
	A0A395H096	Rcd1-domain-containing protein. (388 aa)
	A0A395H234	Uncharacterized protein. (458 aa)
	A0A395H2R1	Pkinase-domain-containing protein. (1085 aa)
	A0A395H964	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (712 aa)
	A0A395HBL2	Cyclin-like protein; Belongs to the cyclin family. (379 aa)
	A0A395HDB9	Pkinase-domain-containing protein. (552 aa)
	A0A395HGJ0	Plus-3-domain-containing protein. (609 aa)
	A0A395HDM8	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1054 aa)
	A0A395HIM5	Serine/threonine protein kinase. (356 aa)
	A0A395HDS2	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (541 aa)

Your Current Organism:

Aspergillus ibericus

NCBI taxonomy Id: 1448316
Other names: A. ibericus CBS 121593, Aspergillus ibericus CBS 121593

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A395GI96	A0A395GL68	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.777
A0A395GI96	A0A395GPR1	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.931
A0A395GI96	A0A395GVY6	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	CDC73-domain-containing protein.	0.962
A0A395GI96	A0A395GX73	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Kinase-like protein.	0.750
A0A395GI96	A0A395GZW9	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.789
A0A395GI96	A0A395H234	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.962
A0A395GI96	A0A395H2R1	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Pkinase-domain-containing protein.	0.830
A0A395GI96	A0A395H964	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.804
A0A395GI96	A0A395HBL2	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Cyclin-like protein; Belongs to the cyclin family.	0.777
A0A395GI96	A0A395HDB9	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Pkinase-domain-containing protein.	0.861
A0A395GI96	A0A395HDM8	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.999
A0A395GI96	A0A395HFD5	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.963
A0A395GI96	A0A395HGJ0	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Plus-3-domain-containing protein.	0.956
A0A395GI96	A0A395HIM5	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Serine/threonine protein kinase.	0.750
A0A395GL68	A0A395GI96	Uncharacterized protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.777
A0A395GL68	A0A395GPA8	Uncharacterized protein.	Sporulation protein.	0.796
A0A395GL68	A0A395GVY6	Uncharacterized protein.	CDC73-domain-containing protein.	0.468
A0A395GL68	A0A395GX73	Uncharacterized protein.	Kinase-like protein.	0.817
A0A395GL68	A0A395GZW9	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.574
A0A395GL68	A0A395H234	Uncharacterized protein.	Uncharacterized protein.	0.545