STRINGSTRING
FEN1 FEN1 A0A395GHD3 A0A395GHD3 A0A395GHH9 A0A395GHH9 A0A395GHM7 A0A395GHM7 A0A395GI43 A0A395GI43 A0A395GI48 A0A395GI48 A0A395GIR1 A0A395GIR1 A0A395GJ47 A0A395GJ47 A0A395GJZ3 A0A395GJZ3 A0A395GK58 A0A395GK58 A0A395GLA7 A0A395GLA7 A0A395GLJ5 A0A395GLJ5 A0A395GLN8 A0A395GLN8 A0A395GLU9 A0A395GLU9 A0A395GLW9 A0A395GLW9 A0A395GLY6 A0A395GLY6 A0A395GMB4 A0A395GMB4 A0A395GNC8 A0A395GNC8 A0A395GNJ3 A0A395GNJ3 A0A395GPF0 A0A395GPF0 A0A395GPV9 A0A395GPV9 A0A395GPZ0 A0A395GPZ0 A0A395GPZ3 A0A395GPZ3 A0A395GQF4 A0A395GQF4 A0A395GQX6 A0A395GQX6 A0A395GR31 A0A395GR31 A0A395GRL1 A0A395GRL1 A0A395GRQ6 A0A395GRQ6 A0A395GRV3 A0A395GRV3 A0A395GSM4 A0A395GSM4 A0A395GSZ8 A0A395GSZ8 A0A395GTN8 A0A395GTN8 A0A395GU15 A0A395GU15 A0A395GU87 A0A395GU87 A0A395GUI9 A0A395GUI9 A0A395GUK7 A0A395GUK7 A0A395GUL7 A0A395GUL7 A0A395GV68 A0A395GV68 A0A395GVF8 A0A395GVF8 A0A395GWB6 A0A395GWB6 A0A395GX81 A0A395GX81 A0A395GXH3 A0A395GXH3 A0A395GXT7 A0A395GXT7 A0A395GY43 A0A395GY43 A0A395GYB4 A0A395GYB4 A0A395GYM0 A0A395GYM0 A0A395GYR4 A0A395GYR4 A0A395GZG7 A0A395GZG7 A0A395GZI7 A0A395GZI7 A0A395H100 A0A395H100 A0A395H1L8 A0A395H1L8 A0A395H1W2 A0A395H1W2 A0A395H281 A0A395H281 A0A395H2M6 A0A395H2M6 A0A395H2Z3 A0A395H2Z3 A0A395H362 A0A395H362 A0A395H368 A0A395H368 A0A395H375 A0A395H375 A0A395H3E5 A0A395H3E5 A0A395H422 A0A395H422 A0A395H485 A0A395H485 A0A395H4K6 A0A395H4K6 A0A395H565 A0A395H565 A0A395H5B1 A0A395H5B1 A0A395H5V9 A0A395H5V9 A0A395H651 A0A395H651 A0A395H7A0 A0A395H7A0 A0A395H7R9 A0A395H7R9 A0A395H970 A0A395H970 A0A395HA74 A0A395HA74 A0A395HAB6 A0A395HAB6 A0A395HAT5 A0A395HAT5 A0A395HAT7 A0A395HAT7 A0A395HB11 A0A395HB11 MCM7 MCM7 A0A395HB43 A0A395HB43 A0A395HBG9 A0A395HBG9 A0A395HBH1 A0A395HBH1 A0A395HBN3 A0A395HBN3 A0A395HBZ1 A0A395HBZ1 A0A395HCF2 A0A395HCF2 A0A395HCS3 A0A395HCS3 A0A395HD45 A0A395HD45 A0A395HDH6 A0A395HDH6 A0A395HDY3 A0A395HDY3 A0A395HFM7 A0A395HFM7 A0A395HH78 A0A395HH78 A0A395HJ71 A0A395HJ71
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
A0A395GHD3Uncharacterized protein. (57 aa)
A0A395GHH9Uncharacterized protein. (126 aa)
A0A395GHM7Uncharacterized protein. (158 aa)
A0A395GI43DNA primase; Belongs to the eukaryotic-type primase small subunit family. (516 aa)
A0A395GI48DBF4-type domain-containing protein. (668 aa)
A0A395GIR1SnoaL-like domain-containing protein. (145 aa)
A0A395GJ47DnaJ domain protein. (319 aa)
A0A395GJZ3Uncharacterized protein. (182 aa)
A0A395GK58P-loop containing nucleoside triphosphate hydrolase protein. (387 aa)
A0A395GLA7Uncharacterized protein. (87 aa)
A0A395GLJ5DNA helicase; Belongs to the MCM family. (1026 aa)
A0A395GLN8Uncharacterized protein. (73 aa)
A0A395GLU9Activator 1 37 kDa subunit. (352 aa)
A0A395GLW9DNA ligase. (886 aa)
A0A395GLY6Uncharacterized protein. (58 aa)
A0A395GMB4Histone-like transcription factor. (188 aa)
A0A395GNC8UBC-like protein; Belongs to the ubiquitin-conjugating enzyme family. (448 aa)
A0A395GNJ3Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (800 aa)
A0A395GPF0P-loop containing nucleoside triphosphate hydrolase protein. (352 aa)
A0A395GPV9Replication protein A, subunit RPA32. (290 aa)
A0A395GPZ0GINS complex, Psf3 component. (178 aa)
A0A395GPZ3Cnn_1N domain-containing protein. (962 aa)
A0A395GQF4Zds_C domain-containing protein. (875 aa)
A0A395GQX6G1/S-specific cyclin; Belongs to the cyclin family. (416 aa)
A0A395GR31Negative regulator of the PHO system; Belongs to the protein kinase superfamily. (292 aa)
A0A395GRL1Uncharacterized protein. (58 aa)
A0A395GRQ6Uncharacterized protein. (70 aa)
A0A395GRV3FAD/NAD(P)-binding domain-containing protein. (532 aa)
A0A395GSM4Cell division control protein 2 kinase; Belongs to the protein kinase superfamily. (323 aa)
A0A395GSZ8Replication factor C subunit 1. (1065 aa)
A0A395GTN8Uncharacterized protein. (57 aa)
A0A395GU15Uncharacterized protein. (120 aa)
A0A395GU87DNA polymerase. (1911 aa)
A0A395GUI9AAA domain-containing protein. (724 aa)
A0A395GUK7DNA helicase; Belongs to the MCM family. (883 aa)
A0A395GUL7DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (269 aa)
A0A395GV68Uncharacterized protein. (63 aa)
A0A395GVF8Replication factor A protein 3. (126 aa)
A0A395GWB6DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2230 aa)
A0A395GX81Cell division control protein; Belongs to the CDC6/cdc18 family. (631 aa)
A0A395GXH3DNA helicase; Belongs to the MCM family. (960 aa)
A0A395GXT7DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (654 aa)
A0A395GY43Proliferating cell nuclear antigen. (615 aa)
A0A395GYB4DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
A0A395GYM0Zf-primase domain-containing protein. (805 aa)
A0A395GYR4Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (258 aa)
A0A395GZG7A/B/D/E cyclin; Belongs to the cyclin family. (480 aa)
A0A395GZI7Uncharacterized protein. (538 aa)
A0A395H100ORC_WH_C domain-containing protein. (698 aa)
A0A395H1L8Uncharacterized protein. (61 aa)
A0A395H1W2DNA helicase; Belongs to the MCM family. (898 aa)
A0A395H281Uncharacterized protein. (721 aa)
A0A395H2M6Negative regulator of the PHO system; Belongs to the protein kinase superfamily. (371 aa)
A0A395H2Z3Telomere length regulation protein Elg1. (1180 aa)
A0A395H362Uncharacterized protein. (197 aa)
A0A395H368Uncharacterized protein. (458 aa)
A0A395H375Ubiquitin-40S ribosomal protein S31 fusion protein. (154 aa)
A0A395H3E5DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (272 aa)
A0A395H422Negative regulator of the PHO system; Belongs to the protein kinase superfamily. (294 aa)
A0A395H485PSF1 domain protein. (223 aa)
A0A395H4K6TPR domain protein. (471 aa)
A0A395H565Uncharacterized protein. (920 aa)
A0A395H5B1ATP-dependent DNA ligase. (999 aa)
A0A395H5V9DNA ligase. (831 aa)
A0A395H651DNA helicase; Belongs to the MCM family. (720 aa)
A0A395H7A0Origin recognition complex subunit 2. (617 aa)
A0A395H7R9AAA domain-containing protein. (757 aa)
A0A395H970Uncharacterized protein. (444 aa)
A0A395HA74DNA polymerase. (1098 aa)
A0A395HAB6Uncharacterized protein. (195 aa)
A0A395HAT5Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (604 aa)
A0A395HAT7Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (635 aa)
A0A395HB11IBB domain-containing protein. (161 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
A0A395HB43Uncharacterized protein. (92 aa)
A0A395HBG9DNA polymerase epsilon subunit B. (754 aa)
A0A395HBH1Uncharacterized protein. (81 aa)
A0A395HBN3Uncharacterized protein. (64 aa)
A0A395HBZ1Uncharacterized protein. (79 aa)
A0A395HCF2RING/U-box. (119 aa)
A0A395HCS3Importin subunit alpha; Belongs to the importin alpha family. (464 aa)
A0A395HD45Reverse transcriptase domain-containing protein. (60 aa)
A0A395HDH6DNA polymerase delta subunit 2. (536 aa)
A0A395HDY3BZIP domain-containing protein. (252 aa)
A0A395HFM7Histone H2B; Belongs to the histone H2B family. (141 aa)
A0A395HH78Kinase-like protein. (490 aa)
A0A395HJ71Putative retrotransposon poly protein. (79 aa)
Your Current Organism:
Aspergillus ibericus
NCBI taxonomy Id: 1448316
Other names: A. ibericus CBS 121593, Aspergillus ibericus CBS 121593
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