(45 nodes) Mixed, incl. Clathrin binding, and Dynamin network (Aspergillus heteromorphus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A317UTW7	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (937 aa)
	A0A317UUQ4	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (984 aa)
	A0A317UXV7	Mitochondrial division protein 1. (654 aa)
	A0A317UZM5	Dynamin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (800 aa)
	A0A317UZX7	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	A0A317V3U8	Cytoskeleton assembly control protein Sla2. (1036 aa)
	A0A317V783	BAR domain protein. (434 aa)
	A0A317VDI5	Protein kinase domain-containing protein. (966 aa)
	A0A317VH90	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (722 aa)
	A0A317VHG3	AP-2 complex subunit MU; Belongs to the adaptor complexes medium subunit family. (442 aa)
	A0A317VIT9	Uncharacterized protein. (394 aa)
	A0A317VKL9	Mitochondrial fission 1 protein; Has a role in mitochondrial fission. (153 aa)
	A0A317VL91	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa)
	A0A317VPB7	CFEM domain-containing protein. (201 aa)
	A0A317VRY1	Tricalbin. (1538 aa)
	A0A317VSM9	AP-1 complex subunit gamma. (842 aa)
	A0A317VTJ1	Uncharacterized protein. (738 aa)
	A0A317VUE9	Uncharacterized protein. (539 aa)
	A0A317VUS8	Putative mitochondrial dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (919 aa)
	A0A317VVP5	Uncharacterized protein. (505 aa)
	A0A317VW01	Cytoskeletal adaptor protein saga. (404 aa)
	A0A317VY25	Ubiquitin-like protein. (248 aa)
	A0A317VZC3	Putative dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (904 aa)
	A0A317W0W9	Uncharacterized protein. (1167 aa)
	A0A317WDQ8	Zn(2)-C6 fungal-type domain-containing protein. (815 aa)
	A0A317WEP9	ARM repeat-containing protein. (823 aa)
	A0A317WIE8	EH domain-containing protein. (498 aa)
	A0A317WKB6	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	A0A317WKI1	UBA/TS-N domain protein. (1262 aa)
	A0A317WMW5	Uncharacterized protein. (1274 aa)
	A0A317WP53	Putative peptidase. (378 aa)
	A0A317WPV3	ENTH-domain-containing protein. (563 aa)
	A0A317WR41	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (246 aa)
	A0A317WS38	Uncharacterized protein. (1190 aa)
	A0A317WT96	AP-3 adaptor complex subunit MU; Belongs to the adaptor complexes medium subunit family. (589 aa)
	A0A317WU43	TAF4 domain-containing protein. (667 aa)
	A0A317WXM8	AP-1 adaptor complex subunit MU; Belongs to the adaptor complexes medium subunit family. (446 aa)
	A0A317WXS2	ENTH-domain-containing protein. (536 aa)
	A0A317WZ93	Maf-domain-containing protein. (477 aa)
	A0A317X0K5	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa)
	A0A317X1L1	RING finger domain protein. (484 aa)
	A0A317X2I2	ENTH domain protein. (621 aa)
	A0A317X2K7	UBA domain-containing protein. (896 aa)
	A0A317X3D3	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (750 aa)
	A0A317X5N3	GED domain-containing protein. (377 aa)

Your Current Organism:

Aspergillus heteromorphus

NCBI taxonomy Id: 1448321
Other names: A. heteromorphus CBS 117.55, Aspergillus heteromorphus CBS 117.55

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A317UTW7	A0A317UUQ4	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.682
A0A317UTW7	A0A317UZM5	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Dynamin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.633
A0A317UTW7	A0A317UZX7	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.996
A0A317UTW7	A0A317VDI5	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Protein kinase domain-containing protein.	0.505
A0A317UTW7	A0A317VH90	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.975
A0A317UTW7	A0A317VHG3	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP-2 complex subunit MU; Belongs to the adaptor complexes medium subunit family.	0.996
A0A317UTW7	A0A317VL91	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.428
A0A317UTW7	A0A317VRY1	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Tricalbin.	0.478
A0A317UTW7	A0A317VSM9	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP-1 complex subunit gamma.	0.692
A0A317UTW7	A0A317VUE9	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Uncharacterized protein.	0.557
A0A317UTW7	A0A317VUS8	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Putative mitochondrial dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.633
A0A317UTW7	A0A317VVP5	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Uncharacterized protein.	0.557
A0A317UTW7	A0A317VW01	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Cytoskeletal adaptor protein saga.	0.557
A0A317UTW7	A0A317VY25	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Ubiquitin-like protein.	0.911
A0A317UTW7	A0A317VZC3	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Putative dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.558
A0A317UTW7	A0A317W0W9	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Uncharacterized protein.	0.557
A0A317UTW7	A0A317WIE8	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	EH domain-containing protein.	0.557
A0A317UTW7	A0A317WKB6	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.868
A0A317UTW7	A0A317WKI1	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	UBA/TS-N domain protein.	0.884
A0A317UTW7	A0A317WMW5	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Uncharacterized protein.	0.478