(16 nodes) Endodeoxyribonuclease activity network (Aspergillus heteromorphus)

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Your Input:
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
	A0A317WWN3	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (818 aa)
	A0A317WI65	Ydc2-catalyt domain-containing protein. (90 aa)
	A0A317WH06	DNA repair protein. (985 aa)
	A0A317W3Q3	Uncharacterized protein. (545 aa)
	A0A317W280	AAA_12 domain-containing protein. (801 aa)
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (422 aa)
	A0A317W0V7	PIN domain-like protein. (1139 aa)
	A0A317VTK3	Uncharacterized protein. (584 aa)
	A0A317VJ25	Zn(2)-C6 fungal-type domain-containing protein. (275 aa)
	A0A317V9M7	Endonuclease. (336 aa)
	A0A317UXI5	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (726 aa)
	A0A317X4X1	PIN domain-like protein. (745 aa)
	BO70DRAFT_2188	Exonuclease. (554 aa)
	SLX4	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (796 aa)
	A0A317X070	Endonuclease MUS81. (577 aa)

Your Current Organism:

Aspergillus heteromorphus

NCBI taxonomy Id: 1448321
Other names: A. heteromorphus CBS 117.55, Aspergillus heteromorphus CBS 117.55

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A317UXI5	A0A317W0V7	A0A317UXI5	A0A317W0V7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	PIN domain-like protein.	0.902
A0A317UXI5	A0A317W280	A0A317UXI5	A0A317W280	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	AAA_12 domain-containing protein.	0.827
A0A317UXI5	A0A317W3Q3	A0A317UXI5	A0A317W3Q3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.869
A0A317UXI5	A0A317WH06	A0A317UXI5	A0A317WH06	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA repair protein.	0.797
A0A317UXI5	A0A317X070	A0A317UXI5	A0A317X070	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Endonuclease MUS81.	0.833
A0A317UXI5	A0A317X4X1	A0A317UXI5	A0A317X4X1	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	PIN domain-like protein.	0.988
A0A317UXI5	BO70DRAFT_2188	A0A317UXI5	A0A317X380	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Exonuclease.	0.902
A0A317UXI5	FEN1	A0A317UXI5	A0A317V0N1	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.981
A0A317V9M7	A0A317W0V7	A0A317V9M7	A0A317W0V7	Endonuclease.	PIN domain-like protein.	0.519
A0A317V9M7	A0A317X4X1	A0A317V9M7	A0A317X4X1	Endonuclease.	PIN domain-like protein.	0.519
A0A317V9M7	BO70DRAFT_2188	A0A317V9M7	A0A317X380	Endonuclease.	Exonuclease.	0.519
A0A317V9M7	FEN1	A0A317V9M7	A0A317V0N1	Endonuclease.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.655
A0A317W0V7	A0A317UXI5	A0A317W0V7	A0A317UXI5	PIN domain-like protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.902
A0A317W0V7	A0A317V9M7	A0A317W0V7	A0A317V9M7	PIN domain-like protein.	Endonuclease.	0.519
A0A317W0V7	A0A317W280	A0A317W0V7	A0A317W280	PIN domain-like protein.	AAA_12 domain-containing protein.	0.779
A0A317W0V7	A0A317W3Q3	A0A317W0V7	A0A317W3Q3	PIN domain-like protein.	Uncharacterized protein.	0.779
A0A317W0V7	A0A317WH06	A0A317W0V7	A0A317WH06	PIN domain-like protein.	DNA repair protein.	0.911
A0A317W0V7	A0A317X070	A0A317W0V7	A0A317X070	PIN domain-like protein.	Endonuclease MUS81.	0.949
A0A317W0V7	A0A317X4X1	A0A317W0V7	A0A317X4X1	PIN domain-like protein.	PIN domain-like protein.	0.467
A0A317W0V7	FEN1	A0A317W0V7	A0A317V0N1	PIN domain-like protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.617