STRINGSTRING
A0A317X6L8 A0A317X6L8 A0A317USD7 A0A317USD7 A0A317UTE9 A0A317UTE9 A0A317UV36 A0A317UV36 A0A317UVZ2 A0A317UVZ2 A0A317UW52 A0A317UW52 A0A317UWY4 A0A317UWY4 A0A317UX14 A0A317UX14 A0A317UXD4 A0A317UXD4 A0A317UYZ2 A0A317UYZ2 A0A317UZH0 A0A317UZH0 A0A317UZI5 A0A317UZI5 A0A317UZI6 A0A317UZI6 A0A317UZU4 A0A317UZU4 FEN1 FEN1 A0A317V191 A0A317V191 A0A317V2W6 A0A317V2W6 A0A317V4N8 A0A317V4N8 A0A317V5G3 A0A317V5G3 A0A317V5R6 A0A317V5R6 A0A317V5X8 A0A317V5X8 A0A317V6F5 A0A317V6F5 A0A317V805 A0A317V805 A0A317V8P6 A0A317V8P6 A0A317VBB8 A0A317VBB8 A0A317VBR0 A0A317VBR0 A0A317VCF4 A0A317VCF4 A0A317VGZ7 A0A317VGZ7 A0A317VH26 A0A317VH26 A0A317VHY4 A0A317VHY4 A0A317VI91 A0A317VI91 A0A317VJ25 A0A317VJ25 MCM7 MCM7 A0A317VL07 A0A317VL07 A0A317VLW6 A0A317VLW6 A0A317VMD8 A0A317VMD8 A0A317VQ60 A0A317VQ60 A0A317VRS9 A0A317VRS9 A0A317VTK3 A0A317VTK3 A0A317VV07 A0A317VV07 A0A317VZ52 A0A317VZ52 A0A317VZS5 A0A317VZS5 A0A317W1Y3 A0A317W1Y3 A0A317W214 A0A317W214 A0A317W280 A0A317W280 A0A317W3Q3 A0A317W3Q3 A0A317X6M9 A0A317X6M9 A0A317W5R7 A0A317W5R7 A0A317X6Z2 A0A317X6Z2 A0A317W5Y7 A0A317W5Y7 A0A317W6G0 A0A317W6G0 A0A317W6I1 A0A317W6I1 A0A317W8C9 A0A317W8C9 A0A317W8I8 A0A317W8I8 A0A317W9U4 A0A317W9U4 A0A317WAM8 A0A317WAM8 A0A317WCT4 A0A317WCT4 A0A317WCT8 A0A317WCT8 A0A317WCW4 A0A317WCW4 A0A317WET2 A0A317WET2 A0A317WHP1 A0A317WHP1 A0A317WI13 A0A317WI13 A0A317WII1 A0A317WII1 A0A317WJL0 A0A317WJL0 A0A317WKG6 A0A317WKG6 A0A317WKQ2 A0A317WKQ2 A0A317WL76 A0A317WL76 A0A317WLF7 A0A317WLF7 A0A317WM05 A0A317WM05 A0A317WMP2 A0A317WMP2 A0A317WNV4 A0A317WNV4 A0A317WQF1 A0A317WQF1 A0A317WRL8 A0A317WRL8 A0A317WRN2 A0A317WRN2 A0A317WRS9 A0A317WRS9 A0A317WS44 A0A317WS44 A0A317WSY4 A0A317WSY4 A0A317WTK4 A0A317WTK4 A0A317WUR8 A0A317WUR8 A0A317WVH1 A0A317WVH1 A0A317WXU0 A0A317WXU0 A0A317WXV8 A0A317WXV8 A0A317WXX5 A0A317WXX5 A0A317WYJ2 A0A317WYJ2 A0A317WZ09 A0A317WZ09 A0A317X035 A0A317X035 A0A317X061 A0A317X061 A0A317X0J1 A0A317X0J1 A0A317X188 A0A317X188 A0A317X1B2 A0A317X1B2 A0A317X259 A0A317X259 A0A317X288 A0A317X288 SLX4 SLX4 A0A317X2F3 A0A317X2F3 BO70DRAFT_2188 BO70DRAFT_2188 A0A317X3T3 A0A317X3T3 A0A317X525 A0A317X525 A0A317X536 A0A317X536 A0A317X6K4 A0A317X6K4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A317X6L8Zf-primase domain-containing protein. (811 aa)
A0A317USD7DNA_pol_E_B domain-containing protein. (751 aa)
A0A317UTE9Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (353 aa)
A0A317UV36Chromosome segregation protein. (841 aa)
A0A317UVZ2Thioredoxin. (583 aa)
A0A317UW52Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (604 aa)
A0A317UWY4Kinase-like protein. (490 aa)
A0A317UX14Uncharacterized protein. (932 aa)
A0A317UXD4Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (267 aa)
A0A317UYZ2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (655 aa)
A0A317UZH0DNA polymerase. (1106 aa)
A0A317UZI5Putative ssDNA binding protein Ssb3. (124 aa)
A0A317UZI6Uncharacterized protein. (147 aa)
A0A317UZU4DNA repair helicase. (827 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
A0A317V191FACT complex subunit spt16. (1020 aa)
A0A317V2W6DNA polymerase gamma. (1135 aa)
A0A317V4N8Ribonucleoside-diphosphate reductase small chain. (401 aa)
A0A317V5G3Cell division control protein; Belongs to the CDC6/cdc18 family. (632 aa)
A0A317V5R6DNA helicase; Belongs to the MCM family. (1029 aa)
A0A317V5X8Uncharacterized protein. (455 aa)
A0A317V6F5DNA ligase. (881 aa)
A0A317V805Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (687 aa)
A0A317V8P6Uncharacterized protein. (197 aa)
A0A317VBB8Replication factor C subunit 1. (1063 aa)
A0A317VBR0AAA domain-containing protein. (583 aa)
A0A317VCF4DUF602-domain-containing protein. (311 aa)
A0A317VGZ7DNA polymerase. (1951 aa)
A0A317VH26CLPTM1 domain protein. (635 aa)
A0A317VHY4ORC_WH_C domain-containing protein. (698 aa)
A0A317VI91AAA domain-containing protein. (724 aa)
A0A317VJ25Zn(2)-C6 fungal-type domain-containing protein. (275 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (806 aa)
A0A317VL07DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (274 aa)
A0A317VLW6SsDNA binding protein. (149 aa)
A0A317VMD8Uncharacterized protein. (2355 aa)
A0A317VQ60Origin recognition complex, subunit 2. (551 aa)
A0A317VRS9DNA-directed polymerase kappa. (608 aa)
A0A317VTK3Uncharacterized protein. (584 aa)
A0A317VV07DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (269 aa)
A0A317VZ52HD domain-containing protein. (236 aa)
A0A317VZS5ATP-dependent RNA helicase SUV3. (762 aa)
A0A317W1Y3DNA helicase; Belongs to the MCM family. (957 aa)
A0A317W214Histone-like transcription factor. (186 aa)
A0A317W280AAA_12 domain-containing protein. (801 aa)
A0A317W3Q3Uncharacterized protein. (545 aa)
A0A317X6M9DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2231 aa)
A0A317W5R7Cell cycle control protein. (671 aa)
A0A317X6Z2Uncharacterized protein. (519 aa)
A0A317W5Y7DNA replication complex GINS protein psf1. (224 aa)
A0A317W6G0DNA polymerase. (1606 aa)
A0A317W6I1Histone-fold-containing protein. (330 aa)
A0A317W8C9SLD3 domain-containing protein. (1005 aa)
A0A317W8I8DNA helicase; Belongs to the MCM family. (1906 aa)
A0A317W9U4CPSF_A domain-containing protein. (1167 aa)
A0A317WAM8Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
A0A317WCT4Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (870 aa)
A0A317WCT8Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (656 aa)
A0A317WCW4Activator 1 37 kDa subunit. (352 aa)
A0A317WET2DNA ligase. (1022 aa)
A0A317WHP1DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1210 aa)
A0A317WI13Uncharacterized protein. (677 aa)
A0A317WII1DNA polymerase delta subunit 2. (542 aa)
A0A317WJL0Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (861 aa)
A0A317WKG6ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (555 aa)
A0A317WKQ2UFD1-domain-containing protein. (364 aa)
A0A317WL76Ribonuclease H-like protein. (274 aa)
A0A317WLF7Nuclear protein localization protein 4. (606 aa)
A0A317WM05Uncharacterized protein. (451 aa)
A0A317WMP2DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
A0A317WNV4Uncharacterized protein. (194 aa)
A0A317WQF1DNA helicase; Belongs to the MCM family. (897 aa)
A0A317WRL8GINS complex, Psf3 component. (178 aa)
A0A317WRN2Kinase-like protein. (1013 aa)
A0A317WRS9P-loop containing nucleoside triphosphate hydrolase protein. (522 aa)
A0A317WS44DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (891 aa)
A0A317WSY4DEAD/DEAH box DNA helicase. (1438 aa)
A0A317WTK4Cnn_1N domain-containing protein. (997 aa)
A0A317WUR8CDC45-like protein. (866 aa)
A0A317WVH1Replication protein A, subunit RPA32. (265 aa)
A0A317WXU0Uncharacterized protein. (414 aa)
A0A317WXV8FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (573 aa)
A0A317WXX5AAA domain-containing protein. (948 aa)
A0A317WYJ2DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
A0A317WZ09WD40 repeat-like protein. (699 aa)
A0A317X035Uncharacterized protein. (102 aa)
A0A317X061MRC1 domain-containing protein. (1217 aa)
A0A317X0J1DNA helicase; Belongs to the MCM family. (720 aa)
A0A317X188Uncharacterized protein. (160 aa)
A0A317X1B2DNA ligase. (835 aa)
A0A317X259DNA primase; Belongs to the eukaryotic-type primase small subunit family. (428 aa)
A0A317X288P-loop containing nucleoside triphosphate hydrolase protein. (385 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (796 aa)
A0A317X2F3AAA domain-containing protein. (765 aa)
BO70DRAFT_2188Exonuclease. (554 aa)
A0A317X3T3DNA_LIGASE_A3 domain-containing protein. (1066 aa)
A0A317X525Sucrase/ferredoxin domain protein. (291 aa)
A0A317X536Uncharacterized protein. (75 aa)
A0A317X6K4Uncharacterized protein. (172 aa)
Your Current Organism:
Aspergillus heteromorphus
NCBI taxonomy Id: 1448321
Other names: A. heteromorphus CBS 117.55, Aspergillus heteromorphus CBS 117.55
Server load: low (14%) [HD]