(23 nodes) Protein targeting to vacuole network (Aspergillus heteromorphus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	A0A317UQT7	Vacuolar protein sorting protein. (621 aa)
	A0A317WTP1	Vesicle-mediated transport protein Vid24. (333 aa)
	A0A317WTT2	Protein kinase. (1610 aa)
	A0A317WXX0	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
	A0A317X0K5	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa)
	A0A317X1E9	Vacuolar assembly protein. (1320 aa)
	A0A317X1M7	Rab GTPase Vps21/Ypt51. (261 aa)
	A0A317X4Z2	Dor1-domain-containing protein. (515 aa)
	A0A317X7D6	Putative endosome-associated ubiquitin isopeptidase. (553 aa)
	A0A317WJ55	Putative SNF7 family protein. (209 aa)
	A0A317WEP9	ARM repeat-containing protein. (823 aa)
	A0A317WCJ8	Ubiquitin conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	A0A317W8Q2	Uncharacterized protein. (536 aa)
	A0A317W5K5	Endosomal peripheral membrane protein. (1727 aa)
	A0A317W2B8	Ubiquitin conjugating enzyme. (139 aa)
	A0A317W233	ESCRT-II complex, vps25 subunit. (188 aa)
	A0A317VX21	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
	A0A317VUJ3	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (262 aa)
	A0A317VJK1	GTP-binding ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	A0A317VD72	Vacuolar fusion protein mon1. (662 aa)
	A0A317UVB9	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (829 aa)
	A0A317UUQ4	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (984 aa)
	A0A317WRM8	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3170 aa)

Your Current Organism:

Aspergillus heteromorphus

NCBI taxonomy Id: 1448321
Other names: A. heteromorphus CBS 117.55, Aspergillus heteromorphus CBS 117.55

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A317UQT7	A0A317VUJ3	Vacuolar protein sorting protein.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.997
A0A317UQT7	A0A317W233	Vacuolar protein sorting protein.	ESCRT-II complex, vps25 subunit.	0.998
A0A317UQT7	A0A317WJ55	Vacuolar protein sorting protein.	Putative SNF7 family protein.	0.570
A0A317UUQ4	A0A317VJK1	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	GTP-binding ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family.	0.591
A0A317UUQ4	A0A317W5K5	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	Endosomal peripheral membrane protein.	0.433
A0A317UUQ4	A0A317WEP9	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	ARM repeat-containing protein.	0.996
A0A317UUQ4	A0A317X0K5	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.588
A0A317UUQ4	A0A317X1E9	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	Vacuolar assembly protein.	0.808
A0A317UUQ4	A0A317X1M7	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	Rab GTPase Vps21/Ypt51.	0.602
A0A317UUQ4	A0A317X4Z2	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	Dor1-domain-containing protein.	0.401
A0A317UVB9	A0A317VD72	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vacuolar fusion protein mon1.	0.559
A0A317UVB9	A0A317X1E9	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vacuolar assembly protein.	0.994
A0A317UVB9	A0A317X1M7	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Rab GTPase Vps21/Ypt51.	0.813
A0A317VD72	A0A317UVB9	Vacuolar fusion protein mon1.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.559
A0A317VD72	A0A317X1E9	Vacuolar fusion protein mon1.	Vacuolar assembly protein.	0.953
A0A317VD72	A0A317X1M7	Vacuolar fusion protein mon1.	Rab GTPase Vps21/Ypt51.	0.542
A0A317VJK1	A0A317UUQ4	GTP-binding ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.591
A0A317VJK1	A0A317W5K5	GTP-binding ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family.	Endosomal peripheral membrane protein.	0.804
A0A317VJK1	A0A317WEP9	GTP-binding ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family.	ARM repeat-containing protein.	0.447
A0A317VJK1	A0A317X1M7	GTP-binding ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family.	Rab GTPase Vps21/Ypt51.	0.485