(37 nodes) Ubiquitin-dependent ERAD pathway network (Aspergillus heteromorphus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A317WC23	IQ and HECT domain protein. (1224 aa)
	A0A317X046	Putative ubiquitin-protein ligase Sel1/Ubx2. (838 aa)
	A0A317X039	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (511 aa)
	A0A317WVJ5	RING-type domain-containing protein. (766 aa)
	A0A317WUE1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (863 aa)
	A0A317WSG8	Protein OS-9. (524 aa)
	A0A317WRI1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (585 aa)
	A0A317WQZ1	UBC-like protein. (231 aa)
	A0A317WPF2	DUF1977-domain-containing protein. (356 aa)
	A0A317WLW7	Putative nuclear pore complex subunit; Belongs to the WD repeat SEC13 family. (309 aa)
	A0A317WLF7	Nuclear protein localization protein 4. (606 aa)
	A0A317WKQ2	UFD1-domain-containing protein. (364 aa)
	A0A317WIN6	U-box domain-containing protein. (1082 aa)
	A0A317WIN0	UBX domain-containing protein. (508 aa)
	A0A317WBT3	N-acetyltransferase. (190 aa)
	A0A317WB38	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (246 aa)
	A0A317W6K7	UBX domain-containing protein. (450 aa)
	A0A317W5W0	Calreticulin-domain-containing protein. (559 aa)
	A0A317W1X3	Putative ubiquitin conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	A0A317W1L0	Ubiquitin conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (246 aa)
	A0A317W134	Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (124 aa)
	A0A317W0T5	J domain-containing protein. (291 aa)
	A0A317VW77	Uncharacterized protein. (1879 aa)
	A0A317VU61	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1086 aa)
	A0A317VQG7	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (695 aa)
	A0A317VP92	26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. (393 aa)
	A0A317VMN0	Transport protein SEC61 subunit alpha. (478 aa)
	A0A317VI90	ANK_REP_REGION domain-containing protein. (643 aa)
	A0A317VEY6	DnaJ domain protein. (422 aa)
	A0A317VC64	DnaK-type molecular chaperone bipA; Belongs to the heat shock protein 70 family. (672 aa)
	A0A317V7Y3	RING finger membrane protein. (1616 aa)
	A0A317V787	Cell division cycle protein 48; Belongs to the AAA ATPase family. (820 aa)
	A0A317V767	UV excision repair protein Rad23. (402 aa)
	A0A317UW54	Uncharacterized protein. (1262 aa)
	A0A317UVI2	OTU-like cysteine protease. (328 aa)
	A0A317USL0	DER1-domain-containing protein. (619 aa)
	A0A317URR9	UBX domain protein. (515 aa)

Your Current Organism:

Aspergillus heteromorphus

NCBI taxonomy Id: 1448321
Other names: A. heteromorphus CBS 117.55, Aspergillus heteromorphus CBS 117.55

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A317URR9	A0A317USL0	UBX domain protein.	DER1-domain-containing protein.	0.846
A0A317URR9	A0A317UVI2	UBX domain protein.	OTU-like cysteine protease.	0.524
A0A317URR9	A0A317UW54	UBX domain protein.	Uncharacterized protein.	0.925
A0A317URR9	A0A317V767	UBX domain protein.	UV excision repair protein Rad23.	0.468
A0A317URR9	A0A317V787	UBX domain protein.	Cell division cycle protein 48; Belongs to the AAA ATPase family.	0.938
A0A317URR9	A0A317V7Y3	UBX domain protein.	RING finger membrane protein.	0.816
A0A317URR9	A0A317VC64	UBX domain protein.	DnaK-type molecular chaperone bipA; Belongs to the heat shock protein 70 family.	0.537
A0A317URR9	A0A317VI90	UBX domain protein.	ANK_REP_REGION domain-containing protein.	0.585
A0A317URR9	A0A317W1X3	UBX domain protein.	Putative ubiquitin conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.852
A0A317URR9	A0A317W6K7	UBX domain protein.	UBX domain-containing protein.	0.930
A0A317URR9	A0A317WB38	UBX domain protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.846
A0A317URR9	A0A317WIN0	UBX domain protein.	UBX domain-containing protein.	0.952
A0A317URR9	A0A317WIN6	UBX domain protein.	U-box domain-containing protein.	0.923
A0A317URR9	A0A317WKQ2	UBX domain protein.	UFD1-domain-containing protein.	0.925
A0A317URR9	A0A317WLF7	UBX domain protein.	Nuclear protein localization protein 4.	0.944
A0A317URR9	A0A317WQZ1	UBX domain protein.	UBC-like protein.	0.451
A0A317URR9	A0A317WSG8	UBX domain protein.	Protein OS-9.	0.942
A0A317URR9	A0A317WVJ5	UBX domain protein.	RING-type domain-containing protein.	0.940
A0A317URR9	A0A317X046	UBX domain protein.	Putative ubiquitin-protein ligase Sel1/Ubx2.	0.677
A0A317USL0	A0A317URR9	DER1-domain-containing protein.	UBX domain protein.	0.846