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| | KALB_1053 | Putative aminotransferase. (365 aa) |
| | KALB_1080 | Putative glutamine synthetase 2. (447 aa) |
| | KALB_1090 | Glutamine synthetase 1. (474 aa) |
| | arcA | Arginine deiminase. (417 aa) |
| | KALB_1231 | Phosphoserine phosphatase. (408 aa) |
| | KALB_133 | Prephenate dehydratase. (306 aa) |
| | KALB_1414 | Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (362 aa) |
| | KALB_1415 | Glutamine synthetase, type III. (460 aa) |
| | KALB_1502 | NAD-specific glutamate dehydrogenase; Involved in arginine catabolism by converting L- glutamate, into 2-oxoglutarate, which is then channeled into the tricarboxylic acid cycle. Can also utilize other amino acids of the glutamate family. (1653 aa) |
| | KALB_1531 | Aminopeptidase with broad substrate specificityto several peptides. Shows strong preference for leucinebut cleaves also next to Arg and lysine inpeptide-bond-containing substrates. (849 aa) |
| | KALB_1554 | Hypothetical protein. (310 aa) |
| | KALB_1556 | Glutamine synthetase. (471 aa) |
| | KALB_1557 | Amidohydrolase 2; Putative metal-dependent TIM-barrel fold hydrolase. (370 aa) |
| | KALB_1558 | Putative membrane protein. (155 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (371 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa) |
| | KALB_1634 | Threonine synthase. (423 aa) |
| | KALB_1867 | Pyridoxal-5'-phosphate-dependent protein subunitbeta. (381 aa) |
| | pepA | Putative cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (497 aa) |
| | gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (367 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa) |
| | KALB_1999 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (462 aa) |
| | KALB_20 | Anthranilate synthase component 2. (214 aa) |
| | KALB_205 | Sarcosine oxidase subunit beta; Glycine/D-amino acid oxidases (deaminating). (380 aa) |
| | KALB_2053 | Anthranilate synthase, phenazine specific; Involved in the biosynthesis of the antibiotic,phenazine, a nitrogen-containing heterocyclic moleculehaving important roles in virulence, competition andbiological control. (601 aa) |
| | KALB_2087 | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (434 aa) |
| | KALB_211 | Prephenate dehydrogenase. (325 aa) |
| | KALB_2195 | Peptidase/hydrolase. (487 aa) |
| | KALB_2196 | Glycine cleavage system protein T; Belongs to the GcvT family. (805 aa) |
| | KALB_2197 | Choline kinase involved in LPS biosynthesis-likeprotein. (302 aa) |
| | KALB_2198 | Amino acid permease family protein. (503 aa) |
| | glsA | Glutaminase; Belongs to the glutaminase family. (303 aa) |
| | KALB_2519 | Hypothetical protein. (522 aa) |
| | KALB_2645 | Catalyzes the interconversion of ornithine to glutamate semialdehyde (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (412 aa) |
| | KALB_269 | Aspartokinase; Belongs to the aspartokinase family. (421 aa) |
| | KALB_270 | Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (356 aa) |
| | KALB_2700 | Putative serine--pyruvate aminotransferase. (364 aa) |
| | KALB_2715 | Shikimate-5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (282 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (396 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (139 aa) |
| | KALB_2773 | Gamma-glutamyltransferase. (584 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa) |
| | KALB_2840 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (368 aa) |
| | KALB_2871 | Hypothetical protein. (120 aa) |
| | hisE | Hypothetical protein. (87 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa) |
| | KALB_3161 | Hypothetical protein. (201 aa) |
| | KALB_3162 | Sarcosine oxidase subunit alpha; Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate; Belongs to the GcvT family. (907 aa) |
| | KALB_3163 | Hypothetical protein. (82 aa) |
| | KALB_3164 | Sarcosine oxidase subunit beta; Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate. (405 aa) |
| | KALB_3171 | Glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. (809 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa) |
| | KALB_3215 | Putative delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (541 aa) |
| | KALB_3216 | Proline dehydrogenase. (308 aa) |
| | KALB_323 | Hypothetical protein. (268 aa) |
| | KALB_3527 | Dihydrodipicolinate synthase; Belongs to the DapA family. (303 aa) |
| | kbl | Putative 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (394 aa) |
| | tdh | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (343 aa) |
| | KALB_3667 | Hypothetical protein. (397 aa) |
| | gcvH | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvP | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (963 aa) |
| | KALB_3738 | Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (396 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (238 aa) |
| | KALB_3997 | Hypothetical protein. (254 aa) |
| | KALB_4273 | Hypothetical protein; Belongs to the peptidase S33 family. (319 aa) |
| | KALB_438 | Aspartokinase; Belongs to the aspartokinase family. (420 aa) |
| | KALB_4638 | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (370 aa) |
| | KALB_4708 | Hypothetical protein; Belongs to the bacterial solute-binding protein 3 family. (278 aa) |
| | KALB_4808 | Hypothetical protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (352 aa) |
| | KALB_5103 | Hypothetical protein. (1503 aa) |
| | KALB_5104 | Hypothetical protein. (479 aa) |
| | KALB_5405 | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (362 aa) |
| | KALB_5508 | Hypothetical protein. (387 aa) |
| | KALB_5520 | Hypothetical protein. (356 aa) |
| | KALB_5574 | Hypothetical protein. (427 aa) |
| | KALB_5658 | Hypothetical protein. (402 aa) |
| | KALB_5659 | Hypothetical protein. (395 aa) |
| | KALB_58 | Gamma-glutamyltransferase. (586 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (378 aa) |
| | KALB_612 | Arginase/agmatinase/formimino glutamase; Belongs to the arginase family. (296 aa) |
| | KALB_6138 | Hypothetical protein. (371 aa) |
| | KALB_6158 | Hypothetical protein. (312 aa) |
| | KALB_6229 | Hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa) |
| | proA-2 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (418 aa) |
| | dapA-2 | Hypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa) |
| | KALB_6447 | Hypothetical protein; Belongs to the DNA glycosylase MPG family. (209 aa) |
| | argH | Hypothetical protein. (470 aa) |
| | argG-2 | Hypothetical protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (398 aa) |
| | argR | Hypothetical protein; Regulates arginine biosynthesis genes. (174 aa) |
| | KALB_6451 | Hypothetical protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (308 aa) |
| | argD | Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (394 aa) |
| | argB | Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa) |
| | argJ | Hypothetical protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (400 aa) |
| | argC | Hypothetical protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa) |
| | KALB_6456 | Hypothetical protein. (267 aa) |
| | KALB_6457 | Hypothetical protein. (47 aa) |
| | KALB_6458 | Hypothetical protein. (117 aa) |
| | KALB_6459 | Hypothetical protein. (265 aa) |
| | KALB_6460 | Hypothetical protein. (184 aa) |
| | KALB_6461 | Hypothetical protein. (272 aa) |
| | KALB_6462 | Hypothetical protein. (124 aa) |
| | KALB_6463 | Hypothetical protein. (107 aa) |
| | dapF | Hypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa) |
| | KALB_6688 | Hypothetical protein. (339 aa) |
| | KALB_6689 | Hypothetical protein. (367 aa) |
| | KALB_6966 | Hypothetical protein. (428 aa) |
| | KALB_7027 | Hypothetical protein. (502 aa) |
| | KALB_7028 | Hypothetical protein. (1523 aa) |
| | trpA | Hypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa) |
| | trpB | Hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa) |
| | trpC | Hypothetical protein; Belongs to the TrpC family. (269 aa) |
| | trpE | Hypothetical protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (513 aa) |
| | hisI | Hypothetical protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (124 aa) |
| | hisF | Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisA | Hypothetical protein. (245 aa) |
| | hisH | Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa) |
| | hisB | Hypothetical protein. (199 aa) |
| | hisC | Hypothetical protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa) |
| | hisD | Hypothetical protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (441 aa) |
| | KALB_7109 | Hypothetical protein. (103 aa) |
| | KALB_7110 | Hypothetical protein. (116 aa) |
| | dapB | Hypothetical protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (265 aa) |
| | KALB_7242 | Hypothetical protein. (307 aa) |
| | pat | Hypothetical protein; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (369 aa) |
| | KALB_7273 | Hypothetical protein. (151 aa) |
| | KALB_7365 | Hypothetical protein; Belongs to the arginase family. (296 aa) |
| | KALB_7452 | Hypothetical protein. (300 aa) |
| | thrB | Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (295 aa) |
| | KALB_7628 | Hypothetical protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (356 aa) |
| | KALB_7629 | Hypothetical protein. (433 aa) |
| | lysA | Hypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (476 aa) |
| | KALB_7632 | Hypothetical protein. (280 aa) |
| | KALB_7633 | Hypothetical protein. (238 aa) |
| | KALB_7719 | Hypothetical protein. (656 aa) |
| | KALB_7802 | Hypothetical protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa) |
| | aroA | Hypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (424 aa) |
| | KALB_7950 | Hypothetical protein. (260 aa) |
| | gcvT-2 | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. (369 aa) |
| | gcvH-2 | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa) |
| | glyA-2 | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa) |
| | KALB_8128 | Hypothetical protein. (89 aa) |
| | KALB_8256 | Hypothetical protein. (409 aa) |
| | KALB_8361 | Hypothetical protein. (324 aa) |
| | proC | Hypothetical protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa) |
| | KALB_8369 | Hypothetical protein. (308 aa) |
| | KALB_8410 | Hypothetical protein. (387 aa) |
| | KALB_846 | Threonine dehydratase. (447 aa) |
| | lysA-2 | Hypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (445 aa) |
| | KALB_8575 | Hypothetical protein. (339 aa) |
| | KALB_8739 | Hypothetical protein. (392 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (297 aa) |
| | KALB_939 | Succinyl-diaminopimelate desuccinylase. (383 aa) |
| | pepA-2 | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (495 aa) |
