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KALB_1053 KALB_1053 KALB_133 KALB_133 KALB_1414 KALB_1414 trpD trpD KALB_1999 KALB_1999 KALB_20 KALB_20 KALB_2053 KALB_2053 KALB_211 KALB_211 KALB_269 KALB_269 KALB_270 KALB_270 KALB_2715 KALB_2715 aroC aroC aroK aroK aroB aroB aroQ aroQ KALB_2871 KALB_2871 hisE hisE hisG hisG KALB_323 KALB_323 KALB_3527 KALB_3527 KALB_3667 KALB_3667 trpF trpF KALB_438 KALB_438 KALB_4708 KALB_4708 KALB_4808 KALB_4808 KALB_5658 KALB_5658 dapA-2 dapA-2 dapF dapF trpA trpA trpB trpB trpC trpC trpE trpE hisI hisI hisF hisF hisA hisA hisH hisH hisB hisB hisC hisC hisD hisD KALB_7109 KALB_7109 KALB_7110 KALB_7110 dapB dapB pat pat KALB_7273 KALB_7273 thrB thrB KALB_7628 KALB_7628 KALB_7629 KALB_7629 lysA lysA KALB_7632 KALB_7632 KALB_7633 KALB_7633 KALB_7719 KALB_7719 aroA aroA KALB_7950 KALB_7950 KALB_8128 KALB_8128 KALB_8256 KALB_8256 KALB_8410 KALB_8410 lysA-2 lysA-2 dapD dapD KALB_939 KALB_939
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KALB_1053Putative aminotransferase. (365 aa)
KALB_133Prephenate dehydratase. (306 aa)
KALB_1414Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (362 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa)
KALB_1999Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (462 aa)
KALB_20Anthranilate synthase component 2. (214 aa)
KALB_2053Anthranilate synthase, phenazine specific; Involved in the biosynthesis of the antibiotic,phenazine, a nitrogen-containing heterocyclic moleculehaving important roles in virulence, competition andbiological control. (601 aa)
KALB_211Prephenate dehydrogenase. (325 aa)
KALB_269Aspartokinase; Belongs to the aspartokinase family. (421 aa)
KALB_270Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (356 aa)
KALB_2715Shikimate-5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (282 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (396 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (139 aa)
KALB_2871Hypothetical protein. (120 aa)
hisEHypothetical protein. (87 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa)
KALB_323Hypothetical protein. (268 aa)
KALB_3527Dihydrodipicolinate synthase; Belongs to the DapA family. (303 aa)
KALB_3667Hypothetical protein. (397 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (238 aa)
KALB_438Aspartokinase; Belongs to the aspartokinase family. (420 aa)
KALB_4708Hypothetical protein; Belongs to the bacterial solute-binding protein 3 family. (278 aa)
KALB_4808Hypothetical protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (352 aa)
KALB_5658Hypothetical protein. (402 aa)
dapA-2Hypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa)
dapFHypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa)
trpAHypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
trpBHypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpCHypothetical protein; Belongs to the TrpC family. (269 aa)
trpEHypothetical protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (513 aa)
hisIHypothetical protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (124 aa)
hisFHypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
hisAHypothetical protein. (245 aa)
hisHHypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa)
hisBHypothetical protein. (199 aa)
hisCHypothetical protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
hisDHypothetical protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (441 aa)
KALB_7109Hypothetical protein. (103 aa)
KALB_7110Hypothetical protein. (116 aa)
dapBHypothetical protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (265 aa)
patHypothetical protein; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (369 aa)
KALB_7273Hypothetical protein. (151 aa)
thrBHypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (295 aa)
KALB_7628Hypothetical protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (356 aa)
KALB_7629Hypothetical protein. (433 aa)
lysAHypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (476 aa)
KALB_7632Hypothetical protein. (280 aa)
KALB_7633Hypothetical protein. (238 aa)
KALB_7719Hypothetical protein. (656 aa)
aroAHypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (424 aa)
KALB_7950Hypothetical protein. (260 aa)
KALB_8128Hypothetical protein. (89 aa)
KALB_8256Hypothetical protein. (409 aa)
KALB_8410Hypothetical protein. (387 aa)
lysA-2Hypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (445 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (297 aa)
KALB_939Succinyl-diaminopimelate desuccinylase. (383 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
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