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gcvT gcvT KALB_205 KALB_205 KALB_2700 KALB_2700 glyA glyA KALB_3161 KALB_3161 KALB_3162 KALB_3162 KALB_3163 KALB_3163 KALB_3164 KALB_3164 KALB_3171 KALB_3171 gcvH gcvH gcvP gcvP KALB_5574 KALB_5574 gcvT-2 gcvT-2 gcvH-2 gcvH-2 glyA-2 glyA-2 KALB_8361 KALB_8361
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (367 aa)
KALB_205Sarcosine oxidase subunit beta; Glycine/D-amino acid oxidases (deaminating). (380 aa)
KALB_2700Putative serine--pyruvate aminotransferase. (364 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
KALB_3161Hypothetical protein. (201 aa)
KALB_3162Sarcosine oxidase subunit alpha; Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate; Belongs to the GcvT family. (907 aa)
KALB_3163Hypothetical protein. (82 aa)
KALB_3164Sarcosine oxidase subunit beta; Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate. (405 aa)
KALB_3171Glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. (809 aa)
gcvHHypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvPGlycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (963 aa)
KALB_5574Hypothetical protein. (427 aa)
gcvT-2Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. (369 aa)
gcvH-2Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
glyA-2Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
KALB_8361Hypothetical protein. (324 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
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