STRINGSTRING
KALB_1539 KALB_1539 KALB_1564 KALB_1564 pfp pfp KALB_1997 KALB_1997 KALB_2003 KALB_2003 KALB_2497 KALB_2497 KALB_2780 KALB_2780 KALB_2801 KALB_2801 pgk pgk tpiA tpiA KALB_2810 KALB_2810 tal tal KALB_2812 KALB_2812 KALB_3566 KALB_3566 ackA ackA KALB_3568 KALB_3568 KALB_3637 KALB_3637 KALB_4168 KALB_4168 KALB_4587 KALB_4587 tal-2 tal-2 KALB_5456 KALB_5456 KALB_5695 KALB_5695 pdxH pdxH pdxT pdxT pdxS pdxS KALB_6737 KALB_6737 KALB_6847 KALB_6847 KALB_7014 KALB_7014 KALB_7055 KALB_7055 KALB_7056 KALB_7056 KALB_7413 KALB_7413 prs prs eno eno gpmA gpmA KALB_8399 KALB_8399 KALB_8550 KALB_8550 KALB_8605 KALB_8605 KALB_8704 KALB_8704 rbsK rbsK KALB_890 KALB_890
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KALB_1539Ribose-5-phosphate isomerase B. (157 aa)
KALB_1564Hypothetical protein. (300 aa)
pfpPyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
KALB_1997Putative ribose-phosphate pyrophosphokinase. (321 aa)
KALB_2003Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
KALB_2497Phosphoglycerate mutase family protein; Fructose-2,6-bisphosphatase. (218 aa)
KALB_2780Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
KALB_2801Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
KALB_2810Glucose-6-phosphate isomerase; Belongs to the GPI family. (539 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (371 aa)
KALB_2812Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (699 aa)
KALB_3566Putative phosphoketolase. (796 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (362 aa)
KALB_3568DoxX family protein. (187 aa)
KALB_3637Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
KALB_4168Hypothetical protein. (305 aa)
KALB_4587Hypothetical protein. (611 aa)
tal-2Hypothetical protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (287 aa)
KALB_5456Hypothetical protein. (334 aa)
KALB_5695Hypothetical protein; Converts alpha-aldose to the beta-anomer. (336 aa)
pdxHPyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (219 aa)
pdxTHypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (205 aa)
pdxSHypothetical protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (299 aa)
KALB_6737Hypothetical protein. (546 aa)
KALB_6847Hypothetical protein. (253 aa)
KALB_7014Hypothetical protein; Belongs to the pyruvate kinase family. (464 aa)
KALB_7055Hypothetical protein. (295 aa)
KALB_7056Hypothetical protein. (225 aa)
KALB_7413Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (532 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
gpmAHypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (245 aa)
KALB_8399Hypothetical protein. (157 aa)
KALB_8550Hypothetical protein. (347 aa)
KALB_8605Hypothetical protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
KALB_8704Hypothetical protein. (301 aa)
rbsKHypothetical protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (297 aa)
KALB_890Fructose-1,6-bisphosphatase class 2; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Seems to be the major FBPase of M.tuberculosis and to play a key role in gluconeogenesis for conversion of lipid carbon into cell wall glycans. Does not display activity against inositol 1-phosphate. (353 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
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