STRINGSTRING
KALB_591 KALB_591 KALB_107 KALB_107 KALB_1071 KALB_1071 panB panB KALB_1320 KALB_1320 KALB_138 KALB_138 KALB_1550 KALB_1550 KALB_1590 KALB_1590 KALB_1647 KALB_1647 panD panD KALB_2243 KALB_2243 KALB_2265 KALB_2265 KALB_2322 KALB_2322 KALB_2331 KALB_2331 KALB_2519 KALB_2519 KALB_2762 KALB_2762 KALB_2773 KALB_2773 glyA glyA KALB_2933 KALB_2933 KALB_2949 KALB_2949 KALB_2950 KALB_2950 egtB egtB egtC egtC egtD egtD folE folE KALB_3161 KALB_3161 KALB_3163 KALB_3163 KALB_3169 KALB_3169 KALB_363 KALB_363 KALB_364 KALB_364 KALB_365 KALB_365 KALB_3702 KALB_3702 panC panC panD-2 panD-2 KALB_3738 KALB_3738 panC-2 panC-2 KALB_4072 KALB_4072 KALB_4127 KALB_4127 KALB_4204 KALB_4204 KALB_4257 KALB_4257 KALB_4638 KALB_4638 KALB_5359 KALB_5359 KALB_5405 KALB_5405 KALB_5493 KALB_5493 KALB_5720 KALB_5720 KALB_5746 KALB_5746 KALB_58 KALB_58 KALB_6019 KALB_6019 KALB_6529 KALB_6529 KALB_653 KALB_653 folD folD KALB_6730 KALB_6730 KALB_746 KALB_746 KALB_7702 KALB_7702 KALB_7719 KALB_7719 KALB_7983 KALB_7983 KALB_7986 KALB_7986 folD-2 folD-2 glyA-2 glyA-2 KALB_945 KALB_945
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KALB_591Glutamate--cysteine ligase GCS2. (498 aa)
KALB_107Hypothetical protein. (117 aa)
KALB_1071Putative protein yqjG. (306 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (297 aa)
KALB_1320Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. (117 aa)
KALB_138Hypothetical protein. (388 aa)
KALB_1550Flavoprotein. (181 aa)
KALB_1590Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (455 aa)
KALB_1647Hypothetical protein. (541 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (140 aa)
KALB_2243Cholesterol oxidase. (505 aa)
KALB_2265Putative cholesterol oxidase. (474 aa)
KALB_2322Hypothetical protein. (178 aa)
KALB_2331Hypothetical protein. (184 aa)
KALB_2519Hypothetical protein. (522 aa)
KALB_2762Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (417 aa)
KALB_2773Gamma-glutamyltransferase. (584 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
KALB_2933Bifunctional deaminase-reductase domain protein. (183 aa)
KALB_2949Hypothetical protein. (192 aa)
KALB_2950Glutamate--cysteine ligase family protein. (318 aa)
egtBHypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. (444 aa)
egtCHypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (255 aa)
egtDMethyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (323 aa)
folEGTP cyclohydrolase I. (194 aa)
KALB_3161Hypothetical protein. (201 aa)
KALB_3163Hypothetical protein. (82 aa)
KALB_3169Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (551 aa)
KALB_363Dihydropteroate synthase 1; DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide (By similarity). (268 aa)
KALB_364Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa)
KALB_3652-amino-4-hydroxy-6- hydroxymethyldihydropteridin epyrophosphokinase. (162 aa)
KALB_3702Hydrolase. (449 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (296 aa)
panD-2Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (155 aa)
KALB_3738Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (396 aa)
panC-2Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (291 aa)
KALB_4072Hypothetical protein; Belongs to the GTP cyclohydrolase I family. (199 aa)
KALB_4127Hypothetical protein. (525 aa)
KALB_4204Hypothetical protein. (180 aa)
KALB_4257Hypothetical protein. (196 aa)
KALB_4638Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (370 aa)
KALB_5359Hypothetical protein. (245 aa)
KALB_5405Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (362 aa)
KALB_5493Hypothetical protein. (207 aa)
KALB_5720Hypothetical protein. (340 aa)
KALB_5746Hypothetical protein. (197 aa)
KALB_58Gamma-glutamyltransferase. (586 aa)
KALB_6019Hypothetical protein. (482 aa)
KALB_6529Hypothetical protein. (200 aa)
KALB_653AIG2 family protein. (348 aa)
folDHypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (273 aa)
KALB_6730Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. (294 aa)
KALB_746Hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (195 aa)
KALB_7702Hypothetical protein. (393 aa)
KALB_7719Hypothetical protein. (656 aa)
KALB_7983Hypothetical protein. (149 aa)
KALB_7986Hypothetical protein; Belongs to the peptidase M20A family. (401 aa)
folD-2Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
glyA-2Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
KALB_945Inactive dihydropteroate synthase 2; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (289 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.