STRINGSTRING
KALB_7051 KALB_7051 KALB_7069 KALB_7069 ftsZ ftsZ KALB_7129 KALB_7129 KALB_7158 KALB_7158 KALB_7159 KALB_7159 KALB_7162 KALB_7162 KALB_72 KALB_72 infB infB KALB_7238 KALB_7238 lon lon KALB_73 KALB_73 ffh ffh ftsY ftsY smc smc kdpB kdpB recG recG KALB_7545 KALB_7545 KALB_7640 KALB_7640 KALB_7787 KALB_7787 rsgA rsgA KALB_7915 KALB_7915 KALB_1093 KALB_1093 KALB_116 KALB_116 KALB_1177 KALB_1177 KALB_1223 KALB_1223 KALB_1259 KALB_1259 KALB_1380 KALB_1380 KALB_1386 KALB_1386 clpX clpX obg obg lepA lepA KALB_1682 KALB_1682 era era KALB_1901 KALB_1901 KALB_1902 KALB_1902 KALB_192 KALB_192 KALB_1988 KALB_1988 KALB_2108 KALB_2108 KALB_2143 KALB_2143 KALB_2225 KALB_2225 KALB_2554 KALB_2554 uvrB uvrB KALB_2638 KALB_2638 KALB_2702 KALB_2702 KALB_2755 KALB_2755 KALB_2857 KALB_2857 KALB_2892 KALB_2892 KALB_290 KALB_290 KALB_291 KALB_291 KALB_2967 KALB_2967 KALB_2980 KALB_2980 hisE hisE arc arc KALB_308 KALB_308 KALB_3315 KALB_3315 KALB_3323 KALB_3323 hppA hppA ppa ppa KALB_3577 KALB_3577 ftsH ftsH KALB_3649 KALB_3649 KALB_3651 KALB_3651 KALB_3725 KALB_3725 KALB_388 KALB_388 KALB_3981 KALB_3981 KALB_4090 KALB_4090 KALB_4108 KALB_4108 KALB_4599 KALB_4599 KALB_4851 KALB_4851 KALB_515 KALB_515 KALB_5234 KALB_5234 KALB_5311 KALB_5311 clpB clpB KALB_5349 KALB_5349 KALB_5391 KALB_5391 KALB_5600 KALB_5600 KALB_5854 KALB_5854 KALB_5863 KALB_5863 htpG htpG ureG ureG KALB_6105 KALB_6105 KALB_6422 KALB_6422 KALB_6429 KALB_6429 uvrA uvrA KALB_6501 KALB_6501 KALB_6524 KALB_6524 KALB_6542 KALB_6542 KALB_6548 KALB_6548 ruvB ruvB ruvA ruvA KALB_6618 KALB_6618 hflX hflX KALB_6837 KALB_6837 dut dut KALB_6986 KALB_6986 uppP uppP KALB_7967 KALB_7967 KALB_799 KALB_799 KALB_8014 KALB_8014 KALB_802 KALB_802 KALB_808 KALB_808 KALB_8127 KALB_8127 guaA guaA tuf tuf fusA fusA KALB_8322 KALB_8322 KALB_8372 KALB_8372 KALB_841 KALB_841 KALB_8439 KALB_8439 clpB-2 clpB-2 KALB_870 KALB_870 KALB_8723 KALB_8723 KALB_8725 KALB_8725 KALB_8763 KALB_8763 KALB_8835 KALB_8835 ychF ychF KALB_921 KALB_921 KALB_963 KALB_963
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KALB_7051Hypothetical protein. (245 aa)
KALB_7069Hypothetical protein; Belongs to the AAA ATPase family. (391 aa)
ftsZHypothetical protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (451 aa)
KALB_7129Hypothetical protein. (380 aa)
KALB_7158Hypothetical protein. (156 aa)
KALB_7159Hypothetical protein. (458 aa)
KALB_7162Hypothetical protein. (1762 aa)
KALB_72Hypothetical protein. (380 aa)
infBHypothetical protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (611 aa)
KALB_7238Hypothetical protein. (655 aa)
lonHypothetical protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (787 aa)
KALB_73Putative membrane protein. (322 aa)
ffhHypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (526 aa)
ftsYHypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (459 aa)
smcHypothetical protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1298 aa)
kdpBHypothetical protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (701 aa)
recGHypothetical protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (730 aa)
KALB_7545Hypothetical protein. (324 aa)
KALB_7640Hypothetical protein. (501 aa)
KALB_7787Hypothetical protein. (280 aa)
rsgAHypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (336 aa)
KALB_7915Hypothetical protein. (179 aa)
KALB_1093Putative DNA helicase II-like protein; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity). (695 aa)
KALB_116Putative protein yehL. (366 aa)
KALB_1177Abolishes the inhibitory effect of oxytetracycline on protein synthesis by a non-covalent modification of the ribosomes. (640 aa)
KALB_1223ATPase involved in chromosome partitioning. (384 aa)
KALB_1259Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (201 aa)
KALB_1380Putative cation-transporting ATPase E. (799 aa)
KALB_1386Superfamily I DNA and RNA helicase-like protein. (664 aa)
clpXATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (426 aa)
obgGTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (486 aa)
lepAElongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (614 aa)
KALB_1682Bifunctional enzyme CysN/CysC; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (439 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (300 aa)
KALB_1901Hypothetical protein. (121 aa)
KALB_1902Hypothetical protein. (132 aa)
KALB_192ABC transporter ATP-binding protein. (752 aa)
KALB_1988Oxyanion-translocating ATPase. (403 aa)
KALB_2108phenylacetate-CoA oxygenase, PaaJ subunit. (166 aa)
KALB_2143Cation-transporting P-type ATPase A. (703 aa)
KALB_2225Putative secreted protein. (124 aa)
KALB_2554Putative protein yeaC. (326 aa)
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (716 aa)
KALB_2638ATP/GTP-binding integral membrane protein; Predicted ATPase. (343 aa)
KALB_2702Putative AAA domain-containing protein. (451 aa)
KALB_2755ATPase. (398 aa)
KALB_2857Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (By similarity). (331 aa)
KALB_2892Hypothetical protein. (632 aa)
KALB_290Putative anion-transporting ATPase; Oxyanion-translocating ATPase. (374 aa)
KALB_291Putative ATPase. (333 aa)
KALB_2967AAA ATPase. (348 aa)
KALB_2980MoxR-like ATPase. (365 aa)
hisEHypothetical protein. (87 aa)
arcProteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (597 aa)
KALB_308NUDIX hydrolase. (230 aa)
KALB_3315Superfamily I DNA and RNA helicases. (722 aa)
KALB_3323Hypothetical protein. (167 aa)
hppAK(+)-insensitive pyrophosphate-energized proton pump; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (762 aa)
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (172 aa)
KALB_3577Sodium/potassium-transporting ATPase, alpha subunit; Cation transport ATPase. (849 aa)
ftsHATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (745 aa)
KALB_3649Putative cation-transporting ATPase F. (845 aa)
KALB_3651Cation transporter atpase p-type. (757 aa)
KALB_3725Predicted metal-sulfur cluster biosynthetic enzyme. (131 aa)
KALB_388Putative ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. (846 aa)
KALB_3981Hypothetical protein. (796 aa)
KALB_4090Hypothetical protein. (249 aa)
KALB_4108Hypothetical protein. (222 aa)
KALB_4599Hypothetical protein. (481 aa)
KALB_4851Hypothetical protein. (262 aa)
KALB_515AAA+ family ATPase; Belongs to the AAA ATPase family. (739 aa)
KALB_5234Hypothetical protein. (1020 aa)
KALB_5311Hypothetical protein. (1406 aa)
clpBHypothetical protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (871 aa)
KALB_5349Hypothetical protein. (131 aa)
KALB_5391Hypothetical protein. (1031 aa)
KALB_5600Hypothetical protein. (688 aa)
KALB_5854Hypothetical protein. (765 aa)
KALB_5863Hypothetical protein. (181 aa)
htpGHypothetical protein; Molecular chaperone. Has ATPase activity. (624 aa)
ureGUrease accessory protein ureG 1; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (230 aa)
KALB_6105Hypothetical protein. (635 aa)
KALB_6422Hypothetical protein. (124 aa)
KALB_6429Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (203 aa)
uvrAHypothetical protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (952 aa)
KALB_6501Hypothetical protein. (1366 aa)
KALB_6524Hypothetical protein. (644 aa)
KALB_6542Hypothetical protein. (98 aa)
KALB_6548Hypothetical protein. (111 aa)
ruvBHypothetical protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (348 aa)
ruvAHypothetical protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (200 aa)
KALB_6618Hypothetical protein. (708 aa)
hflXHypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (480 aa)
KALB_6837Hypothetical protein. (125 aa)
dutHypothetical protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (164 aa)
KALB_6986Hypothetical protein. (866 aa)
uppPHypothetical protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (326 aa)
KALB_7967Hypothetical protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (213 aa)
KALB_799Nucleoside-triphosphate pyrophosphatase. (321 aa)
KALB_8014Hypothetical protein. (396 aa)
KALB_802Superfamily I DNA and RNA helicase-like protein. (725 aa)
KALB_808ppx/GppA family phosphatase. (318 aa)
KALB_8127Hypothetical protein. (787 aa)
guaAHypothetical protein; Catalyzes the synthesis of GMP from XMP. (520 aa)
tufHypothetical protein; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa)
fusAHypothetical protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (699 aa)
KALB_8322Hypothetical protein. (444 aa)
KALB_8372Hypothetical protein. (300 aa)
KALB_841Putative membrane protein. (402 aa)
KALB_8439Hypothetical protein. (752 aa)
clpB-2Hypothetical protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (863 aa)
KALB_870Hypothetical protein. (397 aa)
KALB_8723Hypothetical protein. (612 aa)
KALB_8725Hypothetical protein. (520 aa)
KALB_8763Hypothetical protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (453 aa)
KALB_8835Hypothetical protein. (296 aa)
ychFGTP-dependent nucleic acid-binding protein engD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (359 aa)
KALB_921GTP-binding TypA/BipA-like protein; Not known; probably interacts with the ribosomes in a GTP dependent manner (By similarity). (635 aa)
KALB_963Mrp-like protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (381 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
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