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KALB_1243 KALB_1243 cobT cobT trpD trpD pyrR pyrR hisG hisG KALB_3518 KALB_3518 KALB_360 KALB_360 KALB_4961 KALB_4961 KALB_6601 KALB_6601 hisF hisF hisH hisH kptA kptA KALB_7070 KALB_7070 KALB_7107 KALB_7107 KALB_7989 KALB_7989 upp upp KALB_8022 KALB_8022 KALB_8484 KALB_8484 purF purF pyrE pyrE KALB_8645 KALB_8645
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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KALB_1243Nicotinate phosphoribosyltransferase pncB1; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (427 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (358 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa)
pyrRBifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (195 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa)
KALB_3518Hypothetical protein. (187 aa)
KALB_360Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa)
KALB_4961Hypothetical protein. (515 aa)
KALB_6601Hypothetical protein. (151 aa)
hisFHypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
hisHHypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa)
kptAHypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (187 aa)
KALB_7070Hypothetical protein; Belongs to the NadC/ModD family. (280 aa)
KALB_7107Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (250 aa)
KALB_7989Hypothetical protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa)
uppHypothetical protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)
KALB_8022Hypothetical protein. (429 aa)
KALB_8484Hypothetical protein. (115 aa)
purFHypothetical protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (511 aa)
pyrEHypothetical protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (183 aa)
KALB_8645Hypothetical protein. (219 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
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