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KALB_1954 KALB_1954 KALB_1976 KALB_1976 KALB_2 KALB_2 KALB_1925 KALB_1925 dnaG dnaG KALB_1683 KALB_1683 KALB_1682 KALB_1682 nadD nadD KALB_1501 KALB_1501 KALB_1466 KALB_1466 KALB_1447 KALB_1447 rph rph glnE glnE KALB_2025 KALB_2025 KALB_2068 KALB_2068 dnaX dnaX KALB_2372 KALB_2372 polA polA rpoZ rpoZ KALB_301 KALB_301 KALB_3233 KALB_3233 KALB_337 KALB_337 ispD ispD KALB_4338 KALB_4338 KALB_4467 KALB_4467 KALB_4469 KALB_4469 KALB_4682 KALB_4682 KALB_4805 KALB_4805 KALB_4863 KALB_4863 KALB_533 KALB_533 KALB_5550 KALB_5550 coaD coaD KALB_5986 KALB_5986 KALB_6434 KALB_6434 acuS6 acuS6 KALB_6787 KALB_6787 KALB_6956 KALB_6956 KALB_7084 KALB_7084 KALB_709 KALB_709 KALB_7120 KALB_7120 dinB dinB pnp pnp KALB_7197 KALB_7197 KALB_7221 KALB_7221 KALB_729 KALB_729 KALB_7296 KALB_7296 glnD glnD KALB_7330 KALB_7330 KALB_7331 KALB_7331 coaD-2 coaD-2 fbiD fbiD KALB_7450 KALB_7450 KALB_747 KALB_747 KALB_7852 KALB_7852 glmU glmU KALB_790 KALB_790 KALB_7917 KALB_7917 KALB_8012 KALB_8012 KALB_8076 KALB_8076 dnaE2 dnaE2 KALB_8099 KALB_8099 rpoA rpoA rpoC rpoC rpoB rpoB KALB_8261 KALB_8261 KALB_8268 KALB_8268 KALB_8432 KALB_8432 KALB_8502 KALB_8502 KALB_8551 KALB_8551 KALB_8607 KALB_8607 KALB_8793 KALB_8793 KALB_8797 KALB_8797 KALB_8820 KALB_8820 glgC glgC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KALB_1954Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase. (167 aa)
KALB_1976Hypothetical protein. (572 aa)
KALB_2DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (378 aa)
KALB_1925Diguanylate cyclase. (419 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (631 aa)
KALB_1683Sulfate adenylyltransferase subunit 2. (302 aa)
KALB_1682Bifunctional enzyme CysN/CysC; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (439 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (193 aa)
KALB_1501Hypothetical protein. (997 aa)
KALB_1466GGDEF domain-containing diguanylate cyclase. (418 aa)
KALB_1447Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s). (692 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (263 aa)
glnEGlutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (968 aa)
KALB_2025Hypothetical protein. (243 aa)
KALB_2068Mannose-1-phosphate guanyltransferase. (237 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (700 aa)
KALB_2372Hypothetical protein. (212 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (901 aa)
rpoZHypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (95 aa)
KALB_301DNA polymerase III subunit beta. (363 aa)
KALB_3233Diguanylate cyclase. (499 aa)
KALB_337DNA polymerase III, delta' subunit; ATPase involved in DNA replication. (398 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (228 aa)
KALB_4338Hypothetical protein. (676 aa)
KALB_4467Hypothetical protein. (548 aa)
KALB_4469Hypothetical protein. (163 aa)
KALB_4682Hypothetical protein. (345 aa)
KALB_4805Hypothetical protein. (531 aa)
KALB_4863Hypothetical protein. (389 aa)
KALB_533GGDEF domain-containing diguanylate cyclase. (428 aa)
KALB_5550Hypothetical protein. (528 aa)
coaDHypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (136 aa)
KALB_5986Hypothetical protein. (1122 aa)
KALB_6434Hypothetical protein. (431 aa)
acuS6Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (288 aa)
KALB_6787Hypothetical protein. (338 aa)
KALB_6956Hypothetical protein. (435 aa)
KALB_7084Hypothetical protein. (1184 aa)
KALB_709Diguanylate cyclase. (483 aa)
KALB_7120Hypothetical protein. (410 aa)
dinBHypothetical protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (428 aa)
pnpHypothetical protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (745 aa)
KALB_7197Hypothetical protein; Belongs to the ribF family. (311 aa)
KALB_7221Hypothetical protein. (721 aa)
KALB_729Galactose-1-phosphate uridylyltransferase. (372 aa)
KALB_7296Hypothetical protein; Belongs to the CDS family. (298 aa)
glnDHypothetical protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (788 aa)
KALB_7330Hypothetical protein. (432 aa)
KALB_7331Hypothetical protein. (422 aa)
coaD-2Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
fbiDHypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (211 aa)
KALB_7450Hypothetical protein. (419 aa)
KALB_747Nucleotidyl transferase. (296 aa)
KALB_7852Hypothetical protein. (1078 aa)
glmUBifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (494 aa)
KALB_790Diguanylate cyclase. (569 aa)
KALB_7917Hypothetical protein. (371 aa)
KALB_8012Hypothetical protein. (190 aa)
KALB_8076Hypothetical protein. (316 aa)
dnaE2Hypothetical protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1099 aa)
KALB_8099Hypothetical protein. (522 aa)
rpoAHypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (352 aa)
rpoCHypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1299 aa)
rpoBHypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1160 aa)
KALB_8261Hypothetical protein. (869 aa)
KALB_8268Hypothetical protein; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
KALB_8432Hypothetical protein. (258 aa)
KALB_8502Hypothetical protein. (294 aa)
KALB_8551Hypothetical protein. (718 aa)
KALB_8607Hypothetical protein. (429 aa)
KALB_8793Hypothetical protein. (284 aa)
KALB_8797Hypothetical protein. (398 aa)
KALB_8820Hypothetical protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (512 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (405 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
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