STRINGSTRING
rsmH rsmH KALB_1142 KALB_1142 murG murG ddl ddl murI murI rph rph KALB_1402 KALB_1402 KALB_1436 KALB_1436 KALB_1556 KALB_1556 KALB_1558 KALB_1558 obg obg rsfS rsfS KALB_1628 KALB_1628 KALB_164 KALB_164 KALB_165 KALB_165 KALB_166 KALB_166 KALB_1690 KALB_1690 ybeY ybeY era era KALB_1901 KALB_1901 KALB_1902 KALB_1902 KALB_1959 KALB_1959 murB murB KALB_2024 KALB_2024 KALB_2025 KALB_2025 KALB_2027 KALB_2027 KALB_2108 KALB_2108 KALB_2242 KALB_2242 KALB_23 KALB_23 KALB_2330 KALB_2330 KALB_2333 KALB_2333 KALB_2360 KALB_2360 KALB_2713 KALB_2713 mltG mltG der der KALB_2893 KALB_2893 mraY mraY KALB_3278 KALB_3278 KALB_3307 KALB_3307 KALB_3443 KALB_3443 KALB_3529 KALB_3529 KALB_3530 KALB_3530 KALB_3691 KALB_3691 KALB_3713 KALB_3713 KALB_3718 KALB_3718 KALB_3719 KALB_3719 KALB_3723 KALB_3723 KALB_3725 KALB_3725 KALB_3809 KALB_3809 KALB_3972 KALB_3972 KALB_4035 KALB_4035 KALB_4037 KALB_4037 KALB_4307 KALB_4307 KALB_4314 KALB_4314 KALB_5188 KALB_5188 KALB_5240 KALB_5240 KALB_527 KALB_527 KALB_5757 KALB_5757 KALB_5934 KALB_5934 KALB_6089 KALB_6089 KALB_6096 KALB_6096 KALB_6368 KALB_6368 KALB_6428 KALB_6428 argR argR rplT rplT KALB_6548 KALB_6548 acuAIV acuAIV acuAIII acuAIII KALB_6626 KALB_6626 uppP uppP sepF sepF ftsZ ftsZ KALB_7111 KALB_7111 murC murC murG-2 murG-2 KALB_7114 KALB_7114 murD murD mraY-2 mraY-2 murF murF murE murE KALB_7163 KALB_7163 rnj rnj rbfA rbfA rimP rimP KALB_7224 KALB_7224 rlmN rlmN rimM rimM KALB_7314 KALB_7314 rnc rnc KALB_7355 KALB_7355 KALB_7360 KALB_7360 ddl-2 ddl-2 KALB_7441 KALB_7441 KALB_7464 KALB_7464 KALB_7507 KALB_7507 murA murA KALB_7615 KALB_7615 KALB_7637 KALB_7637 rsmI rsmI rsmA rsmA rsgA rsgA KALB_7876 KALB_7876 glmU glmU KALB_799 KALB_799 KALB_8043 KALB_8043 KALB_8323 KALB_8323 KALB_8324 KALB_8324 KALB_8325 KALB_8325 KALB_8326 KALB_8326 KALB_8385 KALB_8385 murB-2 murB-2 KALB_8442 KALB_8442 KALB_8449 KALB_8449 KALB_8477 KALB_8477 KALB_8717 KALB_8717 KALB_8725 KALB_8725 KALB_8823 KALB_8823 KALB_8833 KALB_8833 rsmG rsmG KALB_889 KALB_889 KALB_921 KALB_921 KALB_963 KALB_963 KALB_995 KALB_995 KALB_996 KALB_996
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rsmHHypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (324 aa)
KALB_1142ATP-dependent helicase HrpB. (810 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (349 aa)
ddlPutative D-alanine--D-lactate ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (344 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (272 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (263 aa)
KALB_1402Regulator. (141 aa)
KALB_1436Mycinamicin-resistance protein myrB; Confers resistance to macrolide, lincosamide and streptogramin B antibiotics; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (294 aa)
KALB_1556Glutamine synthetase. (471 aa)
KALB_1558Putative membrane protein. (155 aa)
obgGTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (486 aa)
rsfSHypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (134 aa)
KALB_1628Hypothetical protein. (239 aa)
KALB_164UDP-galactopyranose mutase; Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate. (408 aa)
KALB_165UDP-galactofuranosyl transferase GlfT2; Involved in the polymerization of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacteria cell wall, through successively beta-D-(1->5) and beta-D-(1->6)- galactofuranosyltransferases activities. It transfers the galactofuranosyl (Galf) unit from UDP-galactofuranosyl (UDP-Galf) onto the galactofuranosyl-rhamnosyl-GlcNAc-pyrophosphoryl- undecaprenyl (Galf-Rha-GlcNAc-PP-C55), yielding polygalactofuranosyl-rhamnosyl-GlcNAc-pyrophosphoryl- undecaprenyl ((Galf)x-Rha-GlcNAc-PP- [...] (643 aa)
KALB_166UDP-galactofuranosyl transferase GlfT1; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. It catalyzes the transfer of the first galactofuranosyl (Galf) unit from UDP- galactofuranosyl (UDP-Galf) onto the rhamnosyl-GlcNAc- pyrophosphoryl-undecaprenyl (Rha-GlcNAc-PP-C55) acceptor through a beta-D-(1->5) or a beta-D-(1->6) galactofuranosyltransferase activitie, yielding galactofuranosyl-rhamnosyl-GlcNAc- pyrophosphoryl-undecaprenyl (Galf-Rha-GlcNAc-PP-C55). GlfT1 [...] (301 aa)
KALB_1690Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (244 aa)
ybeYPutative rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (188 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (300 aa)
KALB_1901Hypothetical protein. (121 aa)
KALB_1902Hypothetical protein. (132 aa)
KALB_1959Iron-sulfur cluster biosynthesis protein; Belongs to the HesB/IscA family. (123 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (371 aa)
KALB_2024Hypothetical protein. (418 aa)
KALB_2025Hypothetical protein. (243 aa)
KALB_2027Hypothetical protein. (125 aa)
KALB_2108phenylacetate-CoA oxygenase, PaaJ subunit. (166 aa)
KALB_2242Hypothetical protein. (314 aa)
KALB_23Penicillin-binding protein A; Cell wall formation. Plays an important role incell division and cell shape maintenance by cross-linkingadjacent peptidoglycan chains through transpeptidation. (495 aa)
KALB_2330Hypothetical protein. (269 aa)
KALB_2333Sporulation and cell division protein SsgA. (141 aa)
KALB_2360Hypothetical protein. (215 aa)
KALB_2713Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (172 aa)
mltGAminodeoxychorismate lyase-like secreted solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (399 aa)
derGTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (471 aa)
KALB_2893Hypothetical protein. (507 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (366 aa)
KALB_3278Non-ribosomal peptide synthetase. (1285 aa)
KALB_3307Hypothetical protein. (313 aa)
KALB_3443Hypothetical protein. (137 aa)
KALB_3529Glutamine amidotransferase. (249 aa)
KALB_3530UDP-N-acetylmuramyl tripeptide synthase. (451 aa)
KALB_3691Hypothetical protein. (432 aa)
KALB_3713MviN-like protein. (542 aa)
KALB_3718FeS cluster assembly protein sufB; The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity). (484 aa)
KALB_3719UPF0051 protein. (393 aa)
KALB_3723SUF system FeS assembly protein; NifU-like protein involved in Fe-S cluster formation. (149 aa)
KALB_3725Predicted metal-sulfur cluster biosynthetic enzyme. (131 aa)
KALB_3809Non-ribosomal peptide synthetase. (1270 aa)
KALB_3972Esterase. (356 aa)
KALB_4035Hypothetical protein. (101 aa)
KALB_4037Hypothetical protein. (784 aa)
KALB_4307Hypothetical protein. (188 aa)
KALB_4314Hypothetical protein. (470 aa)
KALB_5188Hypothetical protein. (237 aa)
KALB_5240Hypothetical protein. (572 aa)
KALB_527Homeostasis protein; Belongs to the CutC family. (226 aa)
KALB_5757Hypothetical protein. (397 aa)
KALB_5934Hypothetical protein. (311 aa)
KALB_6089Hypothetical protein. (343 aa)
KALB_6096Hypothetical protein. (148 aa)
KALB_6368Hypothetical protein. (1308 aa)
KALB_6428Hypothetical protein; Belongs to the pseudouridine synthase RsuA family. (256 aa)
argRHypothetical protein; Regulates arginine biosynthesis genes. (174 aa)
rplTHypothetical protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (124 aa)
KALB_6548Hypothetical protein. (111 aa)
acuAIVPKS I. (3214 aa)
acuAIIIPKS I. (1754 aa)
KALB_6626Hypothetical protein; Belongs to the peptidase S11 family. (415 aa)
uppPHypothetical protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (326 aa)
sepFHypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (212 aa)
ftsZHypothetical protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (451 aa)
KALB_7111Hypothetical protein; Essential cell division protein. (261 aa)
murCHypothetical protein; Cell wall formation; Belongs to the MurCDEF family. (458 aa)
murG-2Hypothetical protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (366 aa)
KALB_7114Hypothetical protein; Belongs to the SEDS family. (495 aa)
murDHypothetical protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (450 aa)
mraY-2Hypothetical protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (365 aa)
murFHypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (482 aa)
murEHypothetical protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (527 aa)
KALB_7163Hypothetical protein. (164 aa)
rnjHypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (565 aa)
rbfAHypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (152 aa)
rimPHypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (173 aa)
KALB_7224Hypothetical protein. (541 aa)
rlmNHypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (368 aa)
rimMHypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (172 aa)
KALB_7314Hypothetical protein; Belongs to the UPF0109 family. (79 aa)
rncHypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (250 aa)
KALB_7355Hypothetical protein. (214 aa)
KALB_7360Hypothetical protein. (183 aa)
ddl-2Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (362 aa)
KALB_7441Hypothetical protein. (297 aa)
KALB_7464Hypothetical protein. (390 aa)
KALB_7507Hypothetical protein. (399 aa)
murAHypothetical protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (422 aa)
KALB_7615Hypothetical protein. (389 aa)
KALB_7637Hypothetical protein. (141 aa)
rsmIRibosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (287 aa)
rsmARibosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (284 aa)
rsgAHypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (336 aa)
KALB_7876Hypothetical protein; Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides. (268 aa)
glmUBifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (494 aa)
KALB_799Nucleoside-triphosphate pyrophosphatase. (321 aa)
KALB_8043Hypothetical protein. (421 aa)
KALB_8323Hypothetical protein. (322 aa)
KALB_8324Hypothetical protein. (521 aa)
KALB_8325Hypothetical protein. (259 aa)
KALB_8326Hypothetical protein. (304 aa)
KALB_8385Hypothetical protein. (388 aa)
murB-2Hypothetical protein; Cell wall formation. (366 aa)
KALB_8442Hypothetical protein. (398 aa)
KALB_8449Hypothetical protein. (404 aa)
KALB_8477Hypothetical protein. (581 aa)
KALB_8717Hypothetical protein. (202 aa)
KALB_8725Hypothetical protein. (520 aa)
KALB_8823Hypothetical protein. (547 aa)
KALB_8833Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (310 aa)
rsmGHypothetical protein; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (228 aa)
KALB_889Hypothetical protein. (203 aa)
KALB_921GTP-binding TypA/BipA-like protein; Not known; probably interacts with the ribosomes in a GTP dependent manner (By similarity). (635 aa)
KALB_963Mrp-like protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (381 aa)
KALB_995Hypothetical protein. (452 aa)
KALB_996DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family. (565 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.