STRINGSTRING
pafA pafA KALB_3658 KALB_3658 KALB_3811 KALB_3811 KALB_3834 KALB_3834 KALB_4462 KALB_4462 KALB_4935 KALB_4935 KALB_4979 KALB_4979 KALB_5154 KALB_5154 KALB_6532 KALB_6532 pnp pnp KALB_7224 KALB_7224 rnhB rnhB KALB_8122 KALB_8122 KALB_8557 KALB_8557 KALB_8558 KALB_8558 KALB_8586 KALB_8586 xseB xseB xseA xseA KALB_996 KALB_996 rph rph KALB_2261 KALB_2261 KALB_2374 KALB_2374 KALB_2465 KALB_2465 arc arc KALB_3046 KALB_3046 pup pup prcB prcB prcA prcA KALB_3538 KALB_3538
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
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pafAPup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. (452 aa)
KALB_3658Hypothetical protein. (208 aa)
KALB_3811Metal dependent phosphohydrolase. (212 aa)
KALB_3834Lysis of cellular walls containing beta-1,3-glucans. Implicated in the defense against fungal pathogens (By similarity). (393 aa)
KALB_4462Hypothetical protein. (918 aa)
KALB_4935Hypothetical protein; Belongs to the glycosyl hydrolase 26 family. (354 aa)
KALB_4979Hypothetical protein. (229 aa)
KALB_5154Hypothetical protein. (394 aa)
KALB_6532Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (128 aa)
pnpHypothetical protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (745 aa)
KALB_7224Hypothetical protein. (541 aa)
rnhBHypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (262 aa)
KALB_8122Hypothetical protein. (758 aa)
KALB_8557Hypothetical protein. (273 aa)
KALB_8558Hypothetical protein. (285 aa)
KALB_8586Hypothetical protein. (90 aa)
xseBHypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (76 aa)
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (416 aa)
KALB_996DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family. (565 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (263 aa)
KALB_2261Lysozyme M1; This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities. (267 aa)
KALB_2374Metal-dependent phosphohydrolase HD sub domain protein. (229 aa)
KALB_2465Putative fibronectin type III domain protein. (839 aa)
arcProteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (597 aa)
KALB_3046Pup deamidase/depupylase; Specifically catalyzes the deamidation of the C-terminal glutamine of the prokaryotic ubiquitin-like protein Pup to glutamate, thereby rendering Pup competent for conjugation. Also displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; is thus involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins (By similarity). (499 aa)
pupHypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family. (64 aa)
prcBProteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. (278 aa)
prcAProteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (245 aa)
KALB_3538Glycosyl hydrolase (secreted protein). (390 aa)
Your Current Organism:
Kutzneria albida
NCBI taxonomy Id: 1449976
Other names: K. albida DSM 43870, Kutzneria albida DSM 43870
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