42 items (Aspergillus sclerotioniger) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	A0A317V528	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (604 aa)
	A0A317UYD7	Kinase-like protein. (515 aa)
	A0A317V4I3	Uncharacterized protein. (588 aa)
	A0A317VGN0	RECA_2 domain-containing protein. (354 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
	A0A317VQC2	MAGE-domain-containing protein. (336 aa)
	A0A317W0R0	DNA polymerase. (1698 aa)
	A0A317W2T3	Sister chromatid cohesion protein. (1771 aa)
	A0A317W4G9	Checkpoint protein; Belongs to the HUS1 family. (349 aa)
	A0A317W5K4	Crossover junction endonuclease mus81. (597 aa)
	A0A317W5Q4	Exonuclease. (554 aa)
	A0A317W5Y5	DNA helicase; Belongs to the MCM family. (720 aa)
	A0A317W950	DHS-like NAD/FAD-binding domain-containing protein. (592 aa)
	A0A317WBE9	Uncharacterized protein. (1027 aa)
	A0A317WG53	Uncharacterized protein. (91 aa)
	A0A317WKB0	Uncharacterized protein. (125 aa)
	A0A317WLH1	Uncharacterized protein. (905 aa)
	A0A317WML3	DNA helicase; Belongs to the MCM family. (898 aa)
	A0A317WN96	Uncharacterized protein. (243 aa)
	A0A317WNG7	Putative RecQ-mediated genome instability protein. (230 aa)
	A0A317WP86	Uncharacterized protein. (446 aa)
	A0A317WQG9	CDC45-like protein. (849 aa)
	A0A317WSL7	Uncharacterized protein. (954 aa)
	A0A317WT40	Uncharacterized protein. (2291 aa)
	A0A317WV07	Uncharacterized protein. (248 aa)
	A0A317WYU2	P-loop containing nucleoside triphosphate hydrolase protein. (1454 aa)
	A0A317X1Q3	DNA repair protein. (976 aa)
	A0A317X3P8	DNA helicase; Belongs to the MCM family. (1026 aa)
	A0A317X648	DNA helicase; Belongs to the MCM family. (960 aa)
	A0A317X7T5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (541 aa)
	A0A317X7W9	Uncharacterized protein. (575 aa)
	A0A317X829	Uncharacterized protein. (1773 aa)
	A0A317X967	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (796 aa)
	A0A317XA47	GINS complex, Psf3 component. (178 aa)
	A0A317XAA7	DNA helicase; Belongs to the MCM family. (886 aa)
	A0A317XAU7	Replication protein A, subunit RPA32. (261 aa)
	A0A317XBF9	Pkinase-domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (2151 aa)
	A0A317XC03	Serine/threonine-protein phosphatase. (426 aa)
	A0A317XC90	Uncharacterized protein. (465 aa)
	A0A317XCT7	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (813 aa)
	A0A317XEQ4	PSF1 domain protein. (223 aa)
	A0A317XHL7	RING-type domain-containing protein. (333 aa)

Your Current Organism:

Aspergillus sclerotioniger

NCBI taxonomy Id: 1450535
Other names: A. sclerotioniger CBS 115572, Aspergillus sclerotioniger CBS 115572

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A317UYD7	A0A317V4I3	A0A317UYD7	A0A317V4I3	Kinase-like protein.	Uncharacterized protein.	0.499
A0A317UYD7	A0A317V528	A0A317UYD7	A0A317V528	Kinase-like protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.707
A0A317UYD7	A0A317W0R0	A0A317UYD7	A0A317W0R0	Kinase-like protein.	DNA polymerase.	0.689
A0A317UYD7	A0A317W5K4	A0A317UYD7	A0A317W5K4	Kinase-like protein.	Crossover junction endonuclease mus81.	0.437
A0A317UYD7	A0A317W5Q4	A0A317UYD7	A0A317W5Q4	Kinase-like protein.	Exonuclease.	0.417
A0A317UYD7	A0A317W5Y5	A0A317UYD7	A0A317W5Y5	Kinase-like protein.	DNA helicase; Belongs to the MCM family.	0.995
A0A317UYD7	A0A317WML3	A0A317UYD7	A0A317WML3	Kinase-like protein.	DNA helicase; Belongs to the MCM family.	0.998
A0A317UYD7	A0A317WN96	A0A317UYD7	A0A317WN96	Kinase-like protein.	Uncharacterized protein.	0.424
A0A317UYD7	A0A317WQG9	A0A317UYD7	A0A317WQG9	Kinase-like protein.	CDC45-like protein.	0.920
A0A317UYD7	A0A317X1Q3	A0A317UYD7	A0A317X1Q3	Kinase-like protein.	DNA repair protein.	0.416
A0A317UYD7	A0A317X3P8	A0A317UYD7	A0A317X3P8	Kinase-like protein.	DNA helicase; Belongs to the MCM family.	0.997
A0A317UYD7	A0A317X648	A0A317UYD7	A0A317X648	Kinase-like protein.	DNA helicase; Belongs to the MCM family.	0.994
A0A317UYD7	A0A317XAA7	A0A317UYD7	A0A317XAA7	Kinase-like protein.	DNA helicase; Belongs to the MCM family.	0.994
A0A317UYD7	A0A317XAU7	A0A317UYD7	A0A317XAU7	Kinase-like protein.	Replication protein A, subunit RPA32.	0.717
A0A317UYD7	MCM7	A0A317UYD7	A0A317VM00	Kinase-like protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.993
A0A317V4I3	A0A317UYD7	A0A317V4I3	A0A317UYD7	Uncharacterized protein.	Kinase-like protein.	0.499
A0A317V4I3	A0A317VQC2	A0A317V4I3	A0A317VQC2	Uncharacterized protein.	MAGE-domain-containing protein.	0.542
A0A317V4I3	A0A317W2T3	A0A317V4I3	A0A317W2T3	Uncharacterized protein.	Sister chromatid cohesion protein.	0.994
A0A317V4I3	A0A317W5K4	A0A317V4I3	A0A317W5K4	Uncharacterized protein.	Crossover junction endonuclease mus81.	0.434
A0A317V4I3	A0A317WYU2	A0A317V4I3	A0A317WYU2	Uncharacterized protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.943