43 items (Aspergillus sclerotioniger) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A317X9B7	Pachytene checkpoint component Pch2. (478 aa)
	A0A317X9T2	DNA repair protein Rad50. (1201 aa)
	A0A317XBX3	DNA mismatch repair protein MutL. (738 aa)
	A0A317XBY2	P-loop containing nucleoside triphosphate hydrolase protein. (1447 aa)
	A0A317XC90	Uncharacterized protein. (465 aa)
	A0A317XEH1	Kinase-like protein; Belongs to the protein kinase superfamily. (370 aa)
	A0A317X859	Meiosis specific protein Hop1. (783 aa)
	A0A317X938	DNA repair protein RAD1. (463 aa)
	A0A317X829	Uncharacterized protein. (1773 aa)
	A0A317X7T6	Polyadenylate-binding protein. (510 aa)
	A0A317X7S9	Apoptosis-inducing TAF9-like domain 1 family protein. (102 aa)
	A0A317X7K9	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1724 aa)
	A0A317X7D8	SUN domain-containing protein. (751 aa)
	A0A317X2S0	Kinase-like protein. (351 aa)
	A0A317X1Q3	DNA repair protein. (976 aa)
	A0A317WYY0	Csm1 domain-containing protein. (514 aa)
	A0A317WYM4	PH domain-containing protein. (1638 aa)
	A0A317WW13	Uncharacterized protein. (736 aa)
	A0A317WVQ3	Rad21_Rec8_N domain-containing protein. (720 aa)
	A0A317WV07	Uncharacterized protein. (248 aa)
	A0A317WSL7	Uncharacterized protein. (954 aa)
	A0A317WNG7	Putative RecQ-mediated genome instability protein. (230 aa)
	A0A317WLD9	Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (216 aa)
	A0A317WK88	S-adenosyl-L-methionine-dependent methyltransferase. (339 aa)
	A0A317WJV9	Putative short-chain dehydrogenases/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
	A0A317WJ78	Uncharacterized protein. (594 aa)
	A0A317WIW5	Meiotic recombination protein spo11. (387 aa)
	A0A317WDE7	DNA mismatch repair protein Msh5. (927 aa)
	A0A317W5K4	Crossover junction endonuclease mus81. (597 aa)
	A0A317W4I5	Aldehyde dehydrogenase-like protein C21C3; Belongs to the aldehyde dehydrogenase family. (630 aa)
	A0A317W2E2	Protein kinase domain-containing protein. (1141 aa)
	A0A317VZJ7	Phosphotransferase enzyme family protein. (373 aa)
	A0A317VZB0	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1119 aa)
	A0A317VVS5	Uncharacterized protein. (630 aa)
	A0A317VIT1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
	A0A317VAQ2	Checkpoint protein kinase. (818 aa)
	A0A317V8V0	Uncharacterized protein. (340 aa)
	A0A317V528	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (604 aa)
	A0A317V2I5	Uncharacterized protein. (287 aa)
	A0A317UZZ5	WD40 repeat-like protein. (311 aa)
	A0A317UZL2	TBPIP domain-containing protein. (203 aa)
	A0A317UYD7	Kinase-like protein. (515 aa)
	A0A317UTC1	Apses transcription factor. (439 aa)

Your Current Organism:

Aspergillus sclerotioniger

NCBI taxonomy Id: 1450535
Other names: A. sclerotioniger CBS 115572, Aspergillus sclerotioniger CBS 115572

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A317UTC1	A0A317X7D8	Apses transcription factor.	SUN domain-containing protein.	0.847
A0A317UYD7	A0A317V528	Kinase-like protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.707
A0A317UYD7	A0A317W2E2	Kinase-like protein.	Protein kinase domain-containing protein.	0.743
A0A317UYD7	A0A317W5K4	Kinase-like protein.	Crossover junction endonuclease mus81.	0.437
A0A317UYD7	A0A317WVQ3	Kinase-like protein.	Rad21_Rec8_N domain-containing protein.	0.522
A0A317UYD7	A0A317X1Q3	Kinase-like protein.	DNA repair protein.	0.416
A0A317UYD7	A0A317X2S0	Kinase-like protein.	Kinase-like protein.	0.653
A0A317UYD7	A0A317X9B7	Kinase-like protein.	Pachytene checkpoint component Pch2.	0.465
A0A317UYD7	A0A317XEH1	Kinase-like protein.	Kinase-like protein; Belongs to the protein kinase superfamily.	0.653
A0A317UZL2	A0A317VZJ7	TBPIP domain-containing protein.	Phosphotransferase enzyme family protein.	0.968
A0A317UZL2	A0A317WIW5	TBPIP domain-containing protein.	Meiotic recombination protein spo11.	0.609
A0A317UZL2	A0A317WK88	TBPIP domain-containing protein.	S-adenosyl-L-methionine-dependent methyltransferase.	0.515
A0A317UZL2	A0A317WLD9	TBPIP domain-containing protein.	Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.	0.987
A0A317UZL2	A0A317X859	TBPIP domain-containing protein.	Meiosis specific protein Hop1.	0.463
A0A317UZL2	A0A317XC90	TBPIP domain-containing protein.	Uncharacterized protein.	0.582
A0A317UZZ5	A0A317WIW5	WD40 repeat-like protein.	Meiotic recombination protein spo11.	0.882
A0A317UZZ5	A0A317WK88	WD40 repeat-like protein.	S-adenosyl-L-methionine-dependent methyltransferase.	0.427
A0A317UZZ5	A0A317WVQ3	WD40 repeat-like protein.	Rad21_Rec8_N domain-containing protein.	0.457
A0A317V528	A0A317UYD7	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	Kinase-like protein.	0.707
A0A317V528	A0A317VIT1	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.984