(141 nodes) Microtubule cytoskeleton network (Aspergillus sclerotioniger)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A317X0Q3	Uncharacterized protein. (183 aa)
	A0A317X2S0	Kinase-like protein. (351 aa)
	A0A317X393	Cell division control protein 2 kinase; Belongs to the protein kinase superfamily. (321 aa)
	A0A317X481	Uncharacterized protein. (1841 aa)
	A0A317X4W6	Uncharacterized protein. (833 aa)
	A0A317X5F7	Uncharacterized protein. (231 aa)
	A0A317X5M0	Uncharacterized protein. (270 aa)
	A0A317X6C7	UPF0187 domain protein. (399 aa)
	A0A317X6I0	Uncharacterized protein. (573 aa)
	A0A317X6K6	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1748 aa)
	A0A317X732	SprT-like domain-containing protein. (731 aa)
	A0A317WVT2	Non-specific serine/threonine protein kinase. (656 aa)
	A0A317WW17	Dynactin. (1359 aa)
	A0A317WXL6	Spc24-domain-containing protein. (200 aa)
	A0A317X734	DASH complex component Dam1. (201 aa)
	A0A317X7D8	SUN domain-containing protein. (751 aa)
	A0A317X7E6	Uncharacterized protein. (140 aa)
	A0A317X861	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (454 aa)
	A0A317X898	Cell division control protein 14. (297 aa)
	A0A317X8C6	ARM repeat-containing protein. (899 aa)
	A0A317X8F1	Trimeric LpxA-like protein. (274 aa)
	A0A317X8F6	Uncharacterized protein. (408 aa)
	A0A317X8F7	Uncharacterized protein. (1303 aa)
	A0A317X8K0	Putative ARS binding protein Abp2. (763 aa)
	A0A317X8N2	Uncharacterized protein. (949 aa)
	A0A317X9C7	Uncharacterized protein. (224 aa)
	A0A317X9K4	NUDE_C domain-containing protein. (611 aa)
	A0A317X9Q2	Tubulin-specific chaperone A; Belongs to the TBCA family. (118 aa)
	A0A317X9Y1	Uncharacterized protein. (275 aa)
	A0A317XA08	Kinase-like protein; Belongs to the protein kinase superfamily. (395 aa)
	A0A317XA50	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (287 aa)
	A0A317XAF0	INCENP_ARK-bind domain-containing protein. (1315 aa)
	A0A317XAU8	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	A0A317XB37	Spindle pole body component. (952 aa)
	A0A317XB45	Uncharacterized protein. (4344 aa)
	A0A317XBI2	Putative tubulin-specific chaperone. (627 aa)
	A0A317XBV3	Uncharacterized protein. (146 aa)
	A0A317XBY7	G-patch domain-containing protein. (252 aa)
	A0A317XC07	Dynactin subunit. (479 aa)
	A0A317USK1	Uncharacterized protein. (291 aa)
	A0A317UTG5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
	A0A317XC73	TCTP family protein; Belongs to the TCTP family. (179 aa)
	A0A317XCF9	ARM repeat-containing protein. (616 aa)
	A0A317XD15	Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (375 aa)
	A0A317XD26	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (748 aa)
	A0A317XD38	Calponin-homology (CH) domain-containing protein. (981 aa)
	A0A317XDA0	Dynein light intermediate chain. (515 aa)
	A0A317WV68	Uncharacterized protein. (778 aa)
	A0A317XDC3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	A0A317XDC4	TBC-domain-containing protein. (458 aa)
	A0A317XDP0	Uncharacterized protein. (280 aa)
	A0A317XDT7	Separin. (2079 aa)
	A0A317XDZ1	Zn(2)-C6 fungal-type domain-containing protein. (763 aa)
	A0A317XEG4	YVTN repeat-like/Quino protein amine dehydrogenase. (489 aa)
	A0A317XEH1	Kinase-like protein; Belongs to the protein kinase superfamily. (370 aa)
	A0A317XF21	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (94 aa)
	A0A317XFZ3	Uncharacterized protein. (349 aa)
	A0A317XGD2	Septin AspB; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (524 aa)
	A0A317UV60	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (801 aa)
	A0A317UVQ5	Uncharacterized protein. (144 aa)
	A0A317UXS0	Cell division/GTP binding protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (346 aa)
	A0A317UYV5	Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (543 aa)
	A0A317VAV0	Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (292 aa)
	A0A317VBV7	Uncharacterized protein. (140 aa)
	A0A317VCN1	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (452 aa)
	A0A317VDL5	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (495 aa)
	A0A317VFJ6	Putative mitochondrial dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (919 aa)
	A0A317VFK6	SH3 domain-containing protein. (724 aa)
	A0A317VG80	GFA domain-containing protein. (112 aa)
	A0A317VG96	CAP-Gly domain-containing protein. (676 aa)
	A0A317VH41	Cytoplasmic dynein intermediate chain. (679 aa)
	A0A317VIZ1	Negative regulator of the PHO system. (276 aa)
	A0A317VJ22	Uncharacterized protein. (2165 aa)
	nudF	Nuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (440 aa)
	A0A317VJX0	Spindle pole body component. (793 aa)
	A0A317VL54	Putative mitotic spindle biogenesis protein Spc19. (167 aa)
	A0A317VLH1	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (953 aa)
	A0A317VLT7	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (926 aa)
	A0A317VMX2	Kinase-like protein; Belongs to the protein kinase superfamily. (427 aa)
	A0A317VNZ2	Amino_oxidase domain-containing protein. (647 aa)
	A0A317VSX3	Ima1_N domain-containing protein. (861 aa)
	A0A317VVI7	Cap-Gly domain-containing protein. (273 aa)
	A0A317VVV3	Uncharacterized protein. (218 aa)
	A0A317VVZ2	Nuclear movement protein nudC. (196 aa)
	A0A317VVZ3	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1085 aa)
	A0A317VWM0	Uncharacterized protein. (841 aa)
	A0A317VXP6	Mov34-domain-containing protein. (358 aa)
	A0A317VYH2	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1185 aa)
	A0A317W0X0	Mo25-like protein. (384 aa)
	A0A317W1D6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (696 aa)
	A0A317W1T0	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (639 aa)
	A0A317W2E2	Protein kinase domain-containing protein. (1141 aa)
	A0A317W2P7	DUF171-domain-containing protein. (834 aa)
	A0A317W2X5	Mis6 domain protein. (732 aa)
	A0A317W2X8	Phosphatases II. (610 aa)
	A0A317W4G9	Checkpoint protein; Belongs to the HUS1 family. (349 aa)
	A0A317W4W9	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (733 aa)
	A0A317W4Z6	Actin-related protein RO7; Belongs to the actin family. (574 aa)
	A0A317W5Q4	Exonuclease. (554 aa)
	A0A317W5W2	Spindle pole body component. (879 aa)
	A0A317WBI0	Uncharacterized protein. (82 aa)
	A0A317WCZ1	GFA domain-containing protein. (163 aa)
	A0A317WBV8	Actin-interacting protein. (1049 aa)
	A0A317WD02	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	A0A317WDI9	Trimeric LpxA-like protein. (201 aa)
	A0A317WDJ8	Uncharacterized protein. (247 aa)
	A0A317WDZ9	Uncharacterized protein. (672 aa)
	A0A317WEV2	Spindle pole body component. (1030 aa)
	A0A317WG98	Spindle pole body component. (890 aa)
	A0A317WGU6	Nuclear protein Es2. (474 aa)
	A0A317WHM1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1164 aa)
	A0A317WIT1	Uncharacterized protein. (248 aa)
	A0A317WJV4	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (722 aa)
	A0A317WJV9	Putative short-chain dehydrogenases/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
	A0A317WK64	rRNA pseudouridine synthase. (499 aa)
	A0A317WKT5	Uncharacterized protein. (989 aa)
	A0A317WLF1	C2 domain protein. (1244 aa)
	A0A317WLH1	Uncharacterized protein. (905 aa)
	A0A317WLH8	EF-hand; Belongs to the calmodulin family. (149 aa)
	A0A317WLP9	GFA domain-containing protein. (140 aa)
	A0A317WM04	Negative regulator of the PHO system. (422 aa)
	A0A317WN20	Uncharacterized protein. (457 aa)
	A0A317WNI0	EF-hand. (269 aa)
	A0A317WQM8	ARF/SAR superfamily; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	A0A317WRY7	DnaJ domain protein. (869 aa)
	A0A317WSG4	Maintenance of ploidy protein mob1. (218 aa)
	A0A317WSS3	Importin subunit beta-2. (937 aa)
	A0A317WSV4	Tubulin-specific chaperone c. (414 aa)
	A0A317WSY6	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (277 aa)
	A0A317WTH4	Uncharacterized protein. (834 aa)
	A0A317WUK2	Uncharacterized protein. (1224 aa)
	A0A317WUR7	Uncharacterized protein. (1003 aa)
	A0A317WXU7	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (743 aa)
	A0A317WY41	Putative glutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (191 aa)
	A0A317WYV6	WD40 repeat-like protein. (1054 aa)
	A0A317WYY0	Csm1 domain-containing protein. (514 aa)
	A0A317WZ16	Uncharacterized protein. (390 aa)
	A0A317WZL8	GTP binding protein. (312 aa)
	A0A317WZM9	Kinase-like protein. (237 aa)
	A0A317WZR0	ADP-ribosylation factor family protein; Belongs to the small GTPase superfamily. Arf family. (183 aa)
	A0A317WZV6	Dynamin family protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (838 aa)

Your Current Organism:

Aspergillus sclerotioniger

NCBI taxonomy Id: 1450535
Other names: A. sclerotioniger CBS 115572, Aspergillus sclerotioniger CBS 115572

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A317USK1	A0A317VLH1	A0A317USK1	A0A317VLH1	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.508
A0A317USK1	A0A317VLT7	A0A317USK1	A0A317VLT7	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.666
A0A317USK1	A0A317VVV3	A0A317USK1	A0A317VVV3	Uncharacterized protein.	Uncharacterized protein.	0.555
A0A317USK1	A0A317VVZ3	A0A317USK1	A0A317VVZ3	Uncharacterized protein.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.508
A0A317USK1	A0A317W4W9	A0A317USK1	A0A317W4W9	Uncharacterized protein.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.508
A0A317USK1	A0A317WXU7	A0A317USK1	A0A317WXU7	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.555
A0A317USK1	A0A317XD26	A0A317USK1	A0A317XD26	Uncharacterized protein.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.508
A0A317UTG5	A0A317VG96	A0A317UTG5	A0A317VG96	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	CAP-Gly domain-containing protein.	0.779
A0A317UTG5	A0A317VH41	A0A317UTG5	A0A317VH41	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Cytoplasmic dynein intermediate chain.	0.975
A0A317UTG5	A0A317VJ22	A0A317UTG5	A0A317VJ22	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.435
A0A317UTG5	A0A317VLH1	A0A317UTG5	A0A317VLH1	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.797
A0A317UTG5	A0A317VLT7	A0A317UTG5	A0A317VLT7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.863
A0A317UTG5	A0A317VMX2	A0A317UTG5	A0A317VMX2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Kinase-like protein; Belongs to the protein kinase superfamily.	0.447
A0A317UTG5	A0A317VVI7	A0A317UTG5	A0A317VVI7	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Cap-Gly domain-containing protein.	0.626
A0A317UTG5	A0A317VVV3	A0A317UTG5	A0A317VVV3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.613
A0A317UTG5	A0A317VVZ3	A0A317UTG5	A0A317VVZ3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.602
A0A317UTG5	A0A317VXP6	A0A317UTG5	A0A317VXP6	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Mov34-domain-containing protein.	0.408
A0A317UTG5	A0A317VYH2	A0A317UTG5	A0A317VYH2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.764
A0A317UTG5	A0A317W2E2	A0A317UTG5	A0A317W2E2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Protein kinase domain-containing protein.	0.826
A0A317UTG5	A0A317W2X5	A0A317UTG5	A0A317W2X5	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Mis6 domain protein.	0.965