Groups of genes that are frequently observed in each other's genomic neighborhood.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Fusion
Genes that are sometimes fused into single open reading frames.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A317VYJ7
Histone-lysine N-methyltransferase. (812 aa)
A0A317WJ82
Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (952 aa)
Your Current Organism:
Aspergillus sclerotioniger
NCBI taxonomy Id: 1450535 Other names: A. sclerotioniger CBS 115572, Aspergillus sclerotioniger CBS 115572
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1
node2
node1 annotation
node2 annotation
score
A0A317VYJ7
A0A317WJ82
Histone-lysine N-methyltransferase.
Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
0.975
A0A317WJ82
A0A317VYJ7
Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
Histone-lysine N-methyltransferase.
0.975
[ The below analysis is limited to the network nodes included in the specified statistical background ]
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