(11 nodes) Non-homologous end-joining, and Single strand break repair network (Aspergillus homomorphus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	A0A395HK49	Putative DSB repair complex subunit Ku70. (654 aa)
	A0A395HKX1	XLF-domain-containing protein. (576 aa)
	A0A395HNZ1	Polynucleotide kinase 3'-phosphatase. (436 aa)
	A0A395HU82	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (722 aa)
	A0A395HYW5	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (628 aa)
	A0A395I2L8	DNA ligase. (1043 aa)
	A0A395I3Z2	Putative hydrolase. (284 aa)
	A0A395I5F6	Terminal deoxynucleotidyl transferase. (657 aa)
	A0A395I9W9	DNA_LIGASE_A3 domain-containing protein. (1033 aa)
	A0A395IBH2	Uncharacterized protein. (767 aa)
	A0A395IBI3	Tyrosyl-DNA phosphodiesterase. (564 aa)

Your Current Organism:

Aspergillus homomorphus

NCBI taxonomy Id: 1450537
Other names: A. homomorphus CBS 101889, Aspergillus homomorphus CBS 101889

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A395HK49	A0A395HKX1	Putative DSB repair complex subunit Ku70.	XLF-domain-containing protein.	0.750
A0A395HK49	A0A395HNZ1	Putative DSB repair complex subunit Ku70.	Polynucleotide kinase 3'-phosphatase.	0.641
A0A395HK49	A0A395HU82	Putative DSB repair complex subunit Ku70.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.999
A0A395HK49	A0A395HYW5	Putative DSB repair complex subunit Ku70.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.868
A0A395HK49	A0A395I2L8	Putative DSB repair complex subunit Ku70.	DNA ligase.	0.997
A0A395HK49	A0A395I3Z2	Putative DSB repair complex subunit Ku70.	Putative hydrolase.	0.489
A0A395HK49	A0A395I5F6	Putative DSB repair complex subunit Ku70.	Terminal deoxynucleotidyl transferase.	0.861
A0A395HK49	A0A395I9W9	Putative DSB repair complex subunit Ku70.	DNA_LIGASE_A3 domain-containing protein.	0.898
A0A395HK49	A0A395IBH2	Putative DSB repair complex subunit Ku70.	Uncharacterized protein.	0.965
A0A395HK49	A0A395IBI3	Putative DSB repair complex subunit Ku70.	Tyrosyl-DNA phosphodiesterase.	0.807
A0A395HKX1	A0A395HK49	XLF-domain-containing protein.	Putative DSB repair complex subunit Ku70.	0.750
A0A395HKX1	A0A395HU82	XLF-domain-containing protein.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.793
A0A395HKX1	A0A395HYW5	XLF-domain-containing protein.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.422
A0A395HKX1	A0A395I2L8	XLF-domain-containing protein.	DNA ligase.	0.821
A0A395HKX1	A0A395I5F6	XLF-domain-containing protein.	Terminal deoxynucleotidyl transferase.	0.422
A0A395HKX1	A0A395I9W9	XLF-domain-containing protein.	DNA_LIGASE_A3 domain-containing protein.	0.595
A0A395HKX1	A0A395IBH2	XLF-domain-containing protein.	Uncharacterized protein.	0.407
A0A395HNZ1	A0A395HK49	Polynucleotide kinase 3'-phosphatase.	Putative DSB repair complex subunit Ku70.	0.641
A0A395HNZ1	A0A395HU82	Polynucleotide kinase 3'-phosphatase.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.574
A0A395HNZ1	A0A395HYW5	Polynucleotide kinase 3'-phosphatase.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.907