STRINGSTRING
A0A395I4L7 A0A395I4L7 A0A395HGY8 A0A395HGY8 SLX4 SLX4 A0A395HJ94 A0A395HJ94 A0A395HNE8 A0A395HNE8 A0A395IAE2 A0A395IAE2 SLX1 SLX1 A0A395HPA2 A0A395HPA2 FEN1 FEN1 A0A395HX30 A0A395HX30 A0A395HXQ8 A0A395HXQ8 A0A395I035 A0A395I035 A0A395IAJ4 A0A395IAJ4 A0A395I2K3 A0A395I2K3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A395I4L7Endonuclease. (332 aa)
A0A395HGY8Crossover junction endonuclease mus81. (587 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (858 aa)
A0A395HJ94Exonuclease. (543 aa)
A0A395HNE8Ribonuclease H-like protein. (366 aa)
A0A395IAE2Uncharacterized protein. (616 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (389 aa)
A0A395HPA2Putative Zn(II)2Cys6 transcription factor. (683 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
A0A395HX30Uncharacterized protein. (767 aa)
A0A395HXQ8Putative DNA repair protein RAD1. (975 aa)
A0A395I035PIN domain-like protein. (1162 aa)
A0A395IAJ4Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (816 aa)
A0A395I2K3Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (862 aa)
Your Current Organism:
Aspergillus homomorphus
NCBI taxonomy Id: 1450537
Other names: A. homomorphus CBS 101889, Aspergillus homomorphus CBS 101889
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