(113 nodes) Regulation of cell cycle process network (Aspergillus homomorphus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	A0A395I6F9	Phosphatases II. (601 aa)
	A0A395I6X1	Cell division control protein; Belongs to the CDC6/cdc18 family. (635 aa)
	A0A395I7G1	Putative serine/threonine protein kinase; Belongs to the protein kinase superfamily. (392 aa)
	A0A395I7N2	CULLIN_2 domain-containing protein; Belongs to the cullin family. (985 aa)
	A0A395I1E0	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (249 aa)
	A0A395I1Y9	Kinase-like protein. (558 aa)
	A0A395I2R2	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (514 aa)
	A0A395I2S2	Serine/threonine-protein phosphatase. (464 aa)
	A0A395I354	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2896 aa)
	A0A395I393	FHA domain protein. (594 aa)
	A0A395I3B2	Uncharacterized protein. (830 aa)
	A0A395I7X0	Putative cell division control protein 2 kinase; Belongs to the protein kinase superfamily. (325 aa)
	A0A395I822	Zn(2)-C6 fungal-type domain-containing protein. (702 aa)
	A0A395I8C2	Putative checkpoint protein kinase. (1226 aa)
	A0A395I8K1	Non-specific serine/threonine protein kinase. (851 aa)
	A0A395I8X9	Uncharacterized protein. (447 aa)
	A0A395I924	WD-repeat-containing protein slp1. (655 aa)
	A0A395I972	Zds_C domain-containing protein. (859 aa)
	A0A395I976	TPR-like protein. (682 aa)
	A0A395I9M5	Nuclear pore complex subunit. (354 aa)
	A0A395IBM6	Protein kinase; Belongs to the protein kinase superfamily. (295 aa)
	A0A395IB77	LIM domain protein. (805 aa)
	A0A395IA00	Uncharacterized protein. (839 aa)
	A0A395IAV8	M protein repeat protein. (738 aa)
	A0A395IAV7	Uncharacterized protein. (456 aa)
	A0A395IAL1	Rhodanese-like protein. (560 aa)
	A0A395IAJ4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (816 aa)
	A0A395IAE8	Rad1-domain-containing protein. (486 aa)
	A0A395IA59	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (532 aa)
	A0A395IA17	Anaphase-promoting complex, Cdc16 subunit. (765 aa)
	A0A395IFC5	Kinase-like protein. (630 aa)
	A0A395IEY2	Uncharacterized protein. (467 aa)
	A0A395I0I4	Putative pachytene checkpoint component Pch2; Belongs to the AAA ATPase family. (483 aa)
	A0A395HZR2	Lysophospholipase. (561 aa)
	A0A395HZ96	GTP binding protein. (312 aa)
	A0A395HYF5	Uncharacterized protein. (1819 aa)
	A0A395HXY1	Spindle pole body component. (960 aa)
	A0A395HXT1	Uncharacterized protein. (423 aa)
	A0A395HXD8	Uncharacterized protein. (474 aa)
	A0A395HWU2	Anaphase-promoting complex subunit 11. (90 aa)
	A0A395HWN8	Kinase-like protein. (786 aa)
	A0A395HWK5	WD40 repeat-like protein. (598 aa)
	A0A395HWK3	Uncharacterized protein. (364 aa)
	A0A395HW51	Velvet domain-containing protein. (268 aa)
	A0A395HW18	Uncharacterized protein. (694 aa)
	A0A395HV98	Spc7-domain-containing protein. (1594 aa)
	BO97DRAFT_8095	Putative Rho guanyl nucleotide exchange factor. (912 aa)
	A0A395IE51	Structural maintenance of chromosomes protein. (1179 aa)
	BO97DRAFT_5460	DBF4-type domain-containing protein. (667 aa)
	A0A395IDK9	Uncharacterized protein. (517 aa)
	A0A395ICH3	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (647 aa)
	A0A395IC16	Maintenance of ploidy protein mob1. (218 aa)
	A0A395HUR0	Uncharacterized protein. (1103 aa)
	A0A395HU43	G1/S-specific cyclin; Belongs to the cyclin family. (418 aa)
	A0A395HTK7	Ca2+/calmodulin-dependent protein kinase. (638 aa)
	A0A395HTC0	Uncharacterized protein. (120 aa)
	A0A395HSQ4	Pkinase-domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	A0A395HS27	MRC1 domain-containing protein. (1409 aa)
	A0A395HS19	Uncharacterized protein. (389 aa)
	A0A395HRV1	Centromere/kinetochore protein Zw10. (828 aa)
	A0A395HRN3	RNA-dependent RNA polymerase. (1374 aa)
	A0A395HRH7	Uncharacterized protein. (109 aa)
	A0A395HRH1	Putative anaphase-promoting complex subunit Apc5. (775 aa)
	A0A395HRA3	Serine/threonine-protein kinase. (1589 aa)
	A0A395HR99	Non-specific serine/threonine protein kinase. (833 aa)
	A0A395HQX5	ARM repeat-containing protein. (616 aa)
	A0A395HQM5	WD repeat-containing protein. (562 aa)
	A0A395HQG3	CBS domain protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (526 aa)
	A0A395HQB8	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	A0A395HQ00	Importin beta-3 subunit. (1095 aa)
	A0A395HPY5	HORMA domain-containing protein. (780 aa)
	A0A395HPX0	Uncharacterized protein. (442 aa)
	A0A395HP70	WD40 repeat-like protein. (819 aa)
	A0A395HP62	mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (172 aa)
	A0A395HMU0	HORMA domain protein. (225 aa)
	A0A395HMK2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (422 aa)
	A0A395HLN5	Checkpoint protein; Belongs to the HUS1 family. (371 aa)
	A0A395HLM5	Pheromone-dependent cell cycle arrest protein Far11. (1069 aa)
	A0A395HLG5	CLPTM1 domain protein. (646 aa)
	A0A395HLD6	Kinase-like protein. (496 aa)
	A0A395HKX4	TBC-domain-containing protein. (487 aa)
	A0A395HKN3	DUF625-domain-containing protein. (883 aa)
	A0A395HKH8	CNH domain protein. (1741 aa)
	A0A395HKH6	Uncharacterized protein. (2078 aa)
	A0A395HKG2	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
	A0A395HK45	WD40 repeat-like protein. (2026 aa)
	A0A395HJ94	Exonuclease. (543 aa)
	A0A395HJ33	Uncharacterized protein. (206 aa)
	A0A395HIX5	Meiosis protein MEI2. (677 aa)
	A0A395HIW2	Zf-PARP-domain-containing protein. (262 aa)
	A0A395HIF8	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (472 aa)
	A0A395HIA3	Uncharacterized protein. (71 aa)
	A0A395HI95	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1008 aa)
	A0A395HI88	Uncharacterized protein. (982 aa)
	A0A395HI45	Serine/threonine protein kinase. (535 aa)
	A0A395HHN2	Uncharacterized protein. (124 aa)
	A0A395HHK4	Negative regulator of the PHO system; Belongs to the protein kinase superfamily. (389 aa)
	A0A395HH84	Serine/threonine-protein kinase. (1120 aa)
	A0A395HGY8	Crossover junction endonuclease mus81. (587 aa)
	A0A395HGK0	Cell cycle checkpoint protein rad17. (751 aa)
	A0A395I3I7	Uncharacterized protein. (286 aa)
	A0A395I3L4	UPF0187-domain-containing protein. (394 aa)
	A0A395I3Y1	Kinase-like protein. (362 aa)
	A0A395I457	Rho GTPase Rho4. (285 aa)
	A0A395I4B0	Kinase-like protein. (1068 aa)
	A0A395I4C0	ERCC4 domain-containing protein. (674 aa)
	A0A395I5R4	DNA-binding cell division cycle control protein. (810 aa)
	A0A395I5T2	Putative PHD transcription factor. (903 aa)
	A0A395I0R8	Cell division control protein 42. (192 aa)
	A0A395I0Y1	Uncharacterized protein. (391 aa)
	A0A395I184	Protein kinase. (1023 aa)
	A0A395I1B1	Serine/threonine-protein phosphatase. (390 aa)
	A0A395I5V4	Uncharacterized protein. (1043 aa)

Your Current Organism:

Aspergillus homomorphus

NCBI taxonomy Id: 1450537
Other names: A. homomorphus CBS 101889, Aspergillus homomorphus CBS 101889

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A395HGK0	A0A395HGY8	A0A395HGK0	A0A395HGY8	Cell cycle checkpoint protein rad17.	Crossover junction endonuclease mus81.	0.733
A0A395HGK0	A0A395HI45	A0A395HGK0	A0A395HI45	Cell cycle checkpoint protein rad17.	Serine/threonine protein kinase.	0.882
A0A395HGK0	A0A395HJ94	A0A395HGK0	A0A395HJ94	Cell cycle checkpoint protein rad17.	Exonuclease.	0.674
A0A395HGK0	A0A395HLD6	A0A395HGK0	A0A395HLD6	Cell cycle checkpoint protein rad17.	Kinase-like protein.	0.494
A0A395HGK0	A0A395HLN5	A0A395HGK0	A0A395HLN5	Cell cycle checkpoint protein rad17.	Checkpoint protein; Belongs to the HUS1 family.	0.991
A0A395HGK0	A0A395HMU0	A0A395HGK0	A0A395HMU0	Cell cycle checkpoint protein rad17.	HORMA domain protein.	0.427
A0A395HGK0	A0A395HS27	A0A395HGK0	A0A395HS27	Cell cycle checkpoint protein rad17.	MRC1 domain-containing protein.	0.801
A0A395HGK0	A0A395HW18	A0A395HGK0	A0A395HW18	Cell cycle checkpoint protein rad17.	Uncharacterized protein.	0.992
A0A395HGK0	A0A395I0I4	A0A395HGK0	A0A395I0I4	Cell cycle checkpoint protein rad17.	Putative pachytene checkpoint component Pch2; Belongs to the AAA ATPase family.	0.421
A0A395HGK0	A0A395I184	A0A395HGK0	A0A395I184	Cell cycle checkpoint protein rad17.	Protein kinase.	0.735
A0A395HGK0	A0A395I1E0	A0A395HGK0	A0A395I1E0	Cell cycle checkpoint protein rad17.	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.787
A0A395HGK0	A0A395I354	A0A395HGK0	A0A395I354	Cell cycle checkpoint protein rad17.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.948
A0A395HGK0	A0A395I3B2	A0A395HGK0	A0A395I3B2	Cell cycle checkpoint protein rad17.	Uncharacterized protein.	0.906
A0A395HGK0	A0A395I3I7	A0A395HGK0	A0A395I3I7	Cell cycle checkpoint protein rad17.	Uncharacterized protein.	0.408
A0A395HGK0	A0A395I3Y1	A0A395HGK0	A0A395I3Y1	Cell cycle checkpoint protein rad17.	Kinase-like protein.	0.669
A0A395HGK0	A0A395I4B0	A0A395HGK0	A0A395I4B0	Cell cycle checkpoint protein rad17.	Kinase-like protein.	0.521
A0A395HGK0	A0A395I6X1	A0A395HGK0	A0A395I6X1	Cell cycle checkpoint protein rad17.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.633
A0A395HGK0	A0A395IAE8	A0A395HGK0	A0A395IAE8	Cell cycle checkpoint protein rad17.	Rad1-domain-containing protein.	0.996
A0A395HGK0	A0A395IAJ4	A0A395HGK0	A0A395IAJ4	Cell cycle checkpoint protein rad17.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.884
A0A395HGY8	A0A395HGK0	A0A395HGY8	A0A395HGK0	Crossover junction endonuclease mus81.	Cell cycle checkpoint protein rad17.	0.733