(68 nodes) protein-DNA complex assembly network (Aspergillus homomorphus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A395HHS2	Uncharacterized protein. (379 aa)
	A0A395HIU4	Putative transcription factor TFIIIB complex subunit Brf1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (1078 aa)
	A0A395HJA0	Uncharacterized protein. (183 aa)
	A0A395HKC7	Nucleosome assembly protein Nap1; Belongs to the nucleosome assembly protein (NAP) family. (409 aa)
	A0A395HL11	Tetratricopeptide repeat domain protein. (438 aa)
	A0A395HLD6	Kinase-like protein. (496 aa)
	A0A395HM90	DNA helicase; Belongs to the MCM family. (897 aa)
	A0A395HMQ0	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (357 aa)
	A0A395HMR2	Acyl_transf_3 domain-containing protein. (469 aa)
	A0A395HMU1	Uncharacterized protein. (103 aa)
	A0A395HNC8	Histone-fold-containing protein. (191 aa)
	A0A395HPX5	Putative DNA repair protein Rex1. (72 aa)
	A0A395HQ27	DNA helicase; Belongs to the MCM family. (883 aa)
	A0A395HQ43	Putative DNA helicase ino80. (1702 aa)
	A0A395HQA8	Histone H2B; Belongs to the histone H2B family. (141 aa)
	A0A395HR83	P-loop containing nucleoside triphosphate hydrolase protein. (1928 aa)
	A0A395HFQ3	Negative cofactor 2 complex subunit beta. (142 aa)
	A0A395HRH0	Uncharacterized protein. (1724 aa)
	A0A395HRN3	RNA-dependent RNA polymerase. (1374 aa)
	A0A395HS11	Uncharacterized protein. (78 aa)
	A0A395HS30	Uncharacterized protein. (446 aa)
	A0A395HS95	Stc1 domain-containing protein. (291 aa)
	A0A395HSL5	Uncharacterized protein. (624 aa)
	A0A395HSX3	TFIID-18kDa-domain-containing protein. (337 aa)
	A0A395HT34	Uncharacterized protein. (680 aa)
	A0A395HT68	Histone H2A; Belongs to the histone H2A family. (138 aa)
	A0A395HUL7	TFIID_20kDa domain-containing protein. (640 aa)
	A0A395HUP6	CENP-T_C domain-containing protein. (477 aa)
	A0A395HV19	Uncharacterized protein. (498 aa)
	A0A395HV84	Silent information regulator protein Sir2p. (579 aa)
	A0A395HV87	Putative chromatin assembly factor 1 subunit B. (722 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (805 aa)
	A0A395HVZ1	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (345 aa)
	A0A395HW67	Uncharacterized protein. (287 aa)
	A0A395HWC3	H15 domain-containing protein. (218 aa)
	A0A395HWS6	Transcription elongation factor TFIIS/Cofactor of enhancer-binding protein. (302 aa)
	A0A395HXW4	Nitrogen regulatory protein OTam. (730 aa)
	A0A395HZ98	DNA helicase; Belongs to the MCM family. (962 aa)
	A0A395HZA3	Uncharacterized protein. (1034 aa)
	A0A395HZN3	Uncharacterized protein. (1948 aa)
	A0A395I069	WD40 repeat-like protein. (336 aa)
	A0A395I0A3	TAFII55_N domain-containing protein. (499 aa)
	A0A395I0Y1	Uncharacterized protein. (391 aa)
	A0A395I175	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	A0A395I221	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (116 aa)
	A0A395I2H1	Putative CBF/NF-Y family transcription factor. (253 aa)
	A0A395I2V7	Uncharacterized protein. (287 aa)
	A0A395I587	DNA helicase; Belongs to the MCM family. (1818 aa)
	A0A395I5B4	Uncharacterized protein. (378 aa)
	A0A395I5J4	Histone-like transcription factor. (188 aa)
	A0A395I6X1	Cell division control protein; Belongs to the CDC6/cdc18 family. (635 aa)
	A0A395I723	P-loop containing nucleoside triphosphate hydrolase protein. (2337 aa)
	A0A395I8M7	CHL4-domain-containing protein. (493 aa)
	A0A395I8Y8	Transcription initiation protein. (345 aa)
	A0A395I9W0	DNA helicase; Belongs to the MCM family. (720 aa)
	A0A395I9Z8	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	A0A395IB99	Trimethylguanosine synthase. (1212 aa)
	A0A395IBD9	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (285 aa)
	A0A395IBW7	FK506-binding protein. (468 aa)
	A0A395ICK8	Uncharacterized protein. (380 aa)
	A0A395ID71	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa)
	A0A395IE73	Uncharacterized protein. (620 aa)
	A0A395IEQ6	TFIID-31kDa-domain-containing protein. (313 aa)
	A0A395IER6	Uncharacterized protein. (282 aa)
	A0A395HG83	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1417 aa)
	A0A395HGL8	Transcription factor IIIB, Bdp1 subunit. (583 aa)
	A0A395HGP1	Uncharacterized protein. (732 aa)
	A0A395HGU6	Transcription initiation factor TFIID complex subunit. (445 aa)

Your Current Organism:

Aspergillus homomorphus

NCBI taxonomy Id: 1450537
Other names: A. homomorphus CBS 101889, Aspergillus homomorphus CBS 101889

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A395HFQ3	A0A395I2H1	A0A395HFQ3	A0A395I2H1	Negative cofactor 2 complex subunit beta.	Putative CBF/NF-Y family transcription factor.	0.988
A0A395HFQ3	A0A395I5J4	A0A395HFQ3	A0A395I5J4	Negative cofactor 2 complex subunit beta.	Histone-like transcription factor.	0.498
A0A395HFQ3	A0A395I8Y8	A0A395HFQ3	A0A395I8Y8	Negative cofactor 2 complex subunit beta.	Transcription initiation protein.	0.613
A0A395HG83	A0A395HQ43	A0A395HG83	A0A395HQ43	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Putative DNA helicase ino80.	0.447
A0A395HG83	A0A395HQA8	A0A395HG83	A0A395HQA8	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Histone H2B; Belongs to the histone H2B family.	0.932
A0A395HG83	A0A395HRH0	A0A395HG83	A0A395HRH0	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Uncharacterized protein.	0.447
A0A395HG83	A0A395HT68	A0A395HG83	A0A395HT68	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Histone H2A; Belongs to the histone H2A family.	0.521
A0A395HG83	A0A395HWS6	A0A395HG83	A0A395HWS6	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Transcription elongation factor TFIIS/Cofactor of enhancer-binding protein.	0.996
A0A395HG83	A0A395I069	A0A395HG83	A0A395I069	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	WD40 repeat-like protein.	0.643
A0A395HG83	A0A395I175	A0A395HG83	A0A395I175	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.749
A0A395HG83	A0A395I221	A0A395HG83	A0A395I221	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.827
A0A395HG83	A0A395I8Y8	A0A395HG83	A0A395I8Y8	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Transcription initiation protein.	0.444
A0A395HG83	A0A395IBD9	A0A395HG83	A0A395IBD9	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.435
A0A395HG83	A0A395ID71	A0A395HG83	A0A395ID71	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.827
A0A395HGL8	A0A395HIU4	A0A395HGL8	A0A395HIU4	Transcription factor IIIB, Bdp1 subunit.	Putative transcription factor TFIIIB complex subunit Brf1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.999
A0A395HGL8	A0A395HRH0	A0A395HGL8	A0A395HRH0	Transcription factor IIIB, Bdp1 subunit.	Uncharacterized protein.	0.571
A0A395HGL8	A0A395HWS6	A0A395HGL8	A0A395HWS6	Transcription factor IIIB, Bdp1 subunit.	Transcription elongation factor TFIIS/Cofactor of enhancer-binding protein.	0.792
A0A395HGL8	A0A395I8Y8	A0A395HGL8	A0A395I8Y8	Transcription factor IIIB, Bdp1 subunit.	Transcription initiation protein.	0.438
A0A395HGL8	A0A395IB99	A0A395HGL8	A0A395IB99	Transcription factor IIIB, Bdp1 subunit.	Trimethylguanosine synthase.	0.449
A0A395HGP1	A0A395HV87	A0A395HGP1	A0A395HV87	Uncharacterized protein.	Putative chromatin assembly factor 1 subunit B.	0.962