STRINGSTRING
bioF bioF AJF87650.1 AJF87650.1 paiA paiA AJF87519.1 AJF87519.1 AJF87490.1 AJF87490.1 AJF87303.1 AJF87303.1 cysE cysE glmU glmU AJF87092.1 AJF87092.1 AJF87060.1 AJF87060.1 dltB dltB AJF86837.1 AJF86837.1 AJF86826.1 AJF86826.1 AJF86812.1 AJF86812.1 eutD eutD lipL lipL AJF86740.1 AJF86740.1 AJF86703.1 AJF86703.1 AJF86696.1 AJF86696.1 fabZ fabZ ggt-2 ggt-2 AJF86550.1 AJF86550.1 AJF86540.1 AJF86540.1 AJF86530.1 AJF86530.1 speG speG AJF86508.1 AJF86508.1 AJF86507.1 AJF86507.1 AJF86489.1 AJF86489.1 AJF86461.1 AJF86461.1 AJF86456.1 AJF86456.1 AJF86357.1 AJF86357.1 tgl tgl bioF-2 bioF-2 AJF86072.1 AJF86072.1 AJF86048.1 AJF86048.1 citZ citZ AJF85938.1 AJF85938.1 leuA leuA lipM lipM AJF85651.1 AJF85651.1 ptb ptb AJF85638.1 AJF85638.1 AJF85605.1 AJF85605.1 AJF85604.1 AJF85604.1 spoVAD spoVAD AJF85491.1 AJF85491.1 AJF85380.1 AJF85380.1 metA metA AJF85355.1 AJF85355.1 AJF85328.1 AJF85328.1 ablB ablB sucB sucB fabD-4 fabD-4 AJF85153.1 AJF85153.1 ggt ggt plsY plsY bltD bltD AJF85030.1 AJF85030.1 AJF85025.1 AJF85025.1 pksR pksR pksN-2 pksN-2 pksM pksM fabF-2 fabF-2 pksN pksN pksG pksG pksF pksF fabD-3 fabD-3 AJF84990.1 AJF84990.1 fabD-2 fabD-2 cat cat fabG-4 fabG-4 fabD fabD plsX plsX AJF84798.1 AJF84798.1 AJF84759.1 AJF84759.1 pdhC pdhC AJF84741.1 AJF84741.1 dapD dapD AJF87694.1 AJF87694.1 AJF84673.1 AJF84673.1 AJF84646.1 AJF84646.1 AJF84597.1 AJF84597.1 AJF84486.1 AJF84486.1 fabI fabI AJF84451.1 AJF84451.1 fabF fabF fabH-2 fabH-2 argJ argJ AJF84407.1 AJF84407.1 AJF84406.1 AJF84406.1 AJF84348.1 AJF84348.1 AJF84342.1 AJF84342.1 AJF84336.1 AJF84336.1 fabH fabH AJF84272.1 AJF84272.1 AJF84263.1 AJF84263.1 citA citA AJF84238.1 AJF84238.1 fabL fabL mprF mprF AJF84159.1 AJF84159.1 AJF84140.1 AJF84140.1 AJF84106.1 AJF84106.1 AJF84090.1 AJF84090.1 AJF84080.1 AJF84080.1 AJF84035.1 AJF84035.1 AJF87664.1 AJF87664.1 AJF84019.1 AJF84019.1 FabZ FabZ AJF84016.1 AJF84016.1 AJF83970.1 AJF83970.1 tsaD tsaD rimI rimI AJF83923.1 AJF83923.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bioF2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (391 aa)
AJF87650.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
paiAGNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
AJF87519.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AJF87490.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
AJF87303.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
cysESerine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (458 aa)
AJF87092.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
AJF87060.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
dltBAlanine transporter; Could be involved in the transport of activated D-alanine through the membrane. (395 aa)
AJF86837.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AJF86826.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
AJF86812.1Spore coat protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
eutDPhosphotransacetylase; In Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
lipLoctanoyl-[GcvH]:protein N-octanoyltransferase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (281 aa)
AJF86740.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
AJF86703.1Pseudaminic acid biosynthesis N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AJF86696.1Phosphinothricin acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
fabZhydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (144 aa)
ggt-2Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
AJF86550.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
AJF86540.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
AJF86530.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arylamine N-acetyltransferase family. (253 aa)
speGSpermidine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
AJF86508.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (339 aa)
AJF86507.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
AJF86489.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AJF86461.1Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AJF86456.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
AJF86357.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
tglTransglutaminase; Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. Belongs to the bacillus TGase family. (245 aa)
bioF-28-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (390 aa)
AJF86072.1Acetoin dehydrogenase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. (210 aa)
AJF86048.1acyl--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
citZCitrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
AJF85938.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (518 aa)
lipMOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (278 aa)
AJF85651.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ptbCatalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
AJF85638.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
AJF85605.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
AJF85604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
spoVADStage V sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AJF85491.1Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
AJF85380.1Chalcone synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
metAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (301 aa)
AJF85355.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
AJF85328.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
ablBAcetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
sucBDihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
fabD-4malonyl-CoA transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AJF85153.1Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3980 aa)
ggtGamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (193 aa)
bltDSpermidine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
AJF85030.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AJF85025.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
pksRPolyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2574 aa)
pksN-2Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (5517 aa)
pksMPolyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (4323 aa)
fabF-2Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (4605 aa)
pksNPolyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (5060 aa)
pksG3-hydroxy-3-methylglutaryl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
pksFPolyketide beta-ketoacyl:ACP synthase; Involved in polyketide production; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (415 aa)
fabD-3Malonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (787 aa)
AJF84990.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
fabD-2Poly(3-hydroxyalkanoate) synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
catChloramphenicol acetyltransferase; This enzyme is an effector of chloramphenicol resistance in bacteria; Belongs to the chloramphenicol acetyltransferase family. (215 aa)
fabG-43-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
fabDMalonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa)
AJF84798.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
AJF84759.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
pdhCBranched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
AJF84741.1Gamma-glutamylcyclotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (236 aa)
AJF87694.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AJF84673.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
AJF84646.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AJF84597.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
AJF84486.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
fabIenoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
AJF84451.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
fabF3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
fabH-23-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (312 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa)
AJF84407.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AJF84406.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AJF84348.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (61 aa)
AJF84342.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AJF84336.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)
AJF84272.1Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (199 aa)
AJF84263.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
citACitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (362 aa)
AJF84238.1Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
fabLenoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
mprFPhosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (855 aa)
AJF84159.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
AJF84140.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AJF84106.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
AJF84090.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
AJF84080.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
AJF84035.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
AJF87664.1Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (313 aa)
AJF84019.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (399 aa)
FabZhydroxymyristoyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AJF84016.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
AJF83970.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
tsaDO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (346 aa)
rimIAlanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (151 aa)
AJF83923.1Alanine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
Your Current Organism:
Bacillus atrophaeus
NCBI taxonomy Id: 1452
Other names: ATCC 49337, B. atrophaeus, Bacillus atriphaeus, Bacillus sp. S2 BC-2, Bacillus subtilis DSM 2277, Bacillus subtilis DSM 675, CCUG 28524, CIP 107159, DSM 7264, IFO 15539, JCM 9070, LMG 16797, LMG:16797, NBRC 15539, NRRL NRS-213
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