STRINGSTRING
ALM06440.1 ALM06440.1 ALM06486.1 ALM06486.1 ALM06501.1 ALM06501.1 ALM06515.1 ALM06515.1 ALM06529.1 ALM06529.1 ALM06576.1 ALM06576.1 ALM06618.1 ALM06618.1 ALM06672.1 ALM06672.1 ALM06676.1 ALM06676.1 ALM06687.1 ALM06687.1 glsA glsA gcvT gcvT ALM06741.1 ALM06741.1 ALM06876.1 ALM06876.1 ackA ackA ALM06942.1 ALM06942.1 ALM06959.1 ALM06959.1 ALM06985.1 ALM06985.1 ALM07013.1 ALM07013.1 ALM07046.1 ALM07046.1 sucD sucD fumC fumC ALM09175.1 ALM09175.1 ALM07278.1 ALM07278.1 ALM07318.1 ALM07318.1 ALM07394.1 ALM07394.1 ALM07396.1 ALM07396.1 ALM07397.1 ALM07397.1 ALM07433.1 ALM07433.1 ALM07494.1 ALM07494.1 ALM07495.1 ALM07495.1 ALM07566.1 ALM07566.1 sucC sucC ALM07609.1 ALM07609.1 icmF icmF purU purU ALM07677.1 ALM07677.1 ALM07678.1 ALM07678.1 mdh mdh asnB asnB ALM07752.1 ALM07752.1 gltA gltA ALM09242.1 ALM09242.1 ALM07928.1 ALM07928.1 pdhA pdhA ALM07935.1 ALM07935.1 ALM07941.1 ALM07941.1 ALM07942.1 ALM07942.1 ALM07943.1 ALM07943.1 gltD gltD ALM07992.1 ALM07992.1 ALM08002.1 ALM08002.1 ALM09247.1 ALM09247.1 ALM08003.1 ALM08003.1 ALM08004.1 ALM08004.1 ALM08134.1 ALM08134.1 ALM08208.1 ALM08208.1 ALM08339.1 ALM08339.1 ALM08385.1 ALM08385.1 sdhA sdhA ALM08387.1 ALM08387.1 ALM08392.1 ALM08392.1 ALM08393.1 ALM08393.1 ALM08519.1 ALM08519.1 ALM09299.1 ALM09299.1 ALM08622.1 ALM08622.1 ALM08641.1 ALM08641.1 ALM08663.1 ALM08663.1 ALM08850.1 ALM08850.1 ALM08862.1 ALM08862.1 ALM08863.1 ALM08863.1 ALM09333.1 ALM09333.1 ALM08909.1 ALM08909.1 gcvH gcvH murI murI ALM08976.1 ALM08976.1 ALM08977.1 ALM08977.1 ALM08978.1 ALM08978.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALM06440.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
ALM06486.1Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ALM06501.1Ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
ALM06515.1Mercuric reductase; Enables the enzymatic reduction of mercuric ions to elemental mercury; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
ALM06529.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
ALM06576.1Diapophytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
ALM06618.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (755 aa)
ALM06672.1Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
ALM06676.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
ALM06687.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
glsAGlutaminase; Catalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family. (304 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (361 aa)
ALM06741.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
ALM06876.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
ALM06942.1Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
ALM06959.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (459 aa)
ALM06985.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa)
ALM07013.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
ALM07046.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
sucDsuccinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
ALM09175.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
ALM07278.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
ALM07318.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
ALM07394.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (801 aa)
ALM07396.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ALM07397.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
ALM07433.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ALM07494.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
ALM07495.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)
ALM07566.1Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
ALM07609.1hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
icmFmethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1144 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
ALM07677.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (728 aa)
ALM07678.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa)
asnBFunctions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
ALM07752.1Na+:solute symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (604 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (428 aa)
ALM09242.1Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. (949 aa)
ALM07928.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (552 aa)
pdhAPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (332 aa)
ALM07935.1Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
ALM07941.1Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
ALM07942.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
ALM07943.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1502 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
ALM07992.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ALM08002.1acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
ALM09247.1Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (480 aa)
ALM08003.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
ALM08004.1acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
ALM08134.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ALM08208.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
ALM08339.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
ALM08385.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (667 aa)
ALM08387.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (248 aa)
ALM08392.1succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
ALM08393.1succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
ALM08519.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
ALM09299.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
ALM08622.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (517 aa)
ALM08641.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
ALM08663.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
ALM08850.1Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
ALM08862.12-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (933 aa)
ALM08863.12-oxoglutarate dehydrogenase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (409 aa)
ALM09333.11-alkyl-2-acetylglycerophosphocholine esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ALM08909.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (765 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (262 aa)
ALM08976.1Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
ALM08977.1Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
ALM08978.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
Your Current Organism:
Sediminicola sp. YIK13
NCBI taxonomy Id: 1453352
Other names: S. sp. YIK13
Server load: low (12%) [HD]