STRINGSTRING
bioD bioD accD accD lipA lipA ALM06607.1 ALM06607.1 accA accA ALM09126.1 ALM09126.1 ALM06856.1 ALM06856.1 ALM06864.1 ALM06864.1 ALM06876.1 ALM06876.1 ackA ackA ALM06991.1 ALM06991.1 ALM07117.1 ALM07117.1 cysM cysM ALM07207.1 ALM07207.1 ALM09173.1 ALM09173.1 ALM07798.1 ALM07798.1 folD folD ALM07928.1 ALM07928.1 pdhA pdhA ALM08004.1 ALM08004.1 dxs dxs thiL thiL ALM08504.1 ALM08504.1 ALM09292.1 ALM09292.1 ALM08688.1 ALM08688.1 bioB bioB ALM09332.1 ALM09332.1 ALM08978.1 ALM08978.1 metK metK ALM09343.1 ALM09343.1 ALM08992.1 ALM08992.1 ALM08996.1 ALM08996.1 ALM08997.1 ALM08997.1 ALM09352.1 ALM09352.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bioDATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (205 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (288 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (291 aa)
ALM06607.1Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
accAacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
ALM09126.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
ALM06856.1LmbE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (844 aa)
ALM06864.1GlcNAc-PI de-N-acetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
ALM06876.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
ALM06991.1Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
ALM07117.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
cysMCysteine synthase; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (294 aa)
ALM07207.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
ALM09173.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
ALM07798.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
folD5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
ALM07928.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (552 aa)
pdhAPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (332 aa)
ALM08004.1acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (587 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (349 aa)
ALM08504.1CBS domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
ALM09292.1S-adenosylmethionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
ALM08688.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (364 aa)
ALM09332.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
ALM08978.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (418 aa)
ALM09343.1Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
ALM08992.1Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (415 aa)
ALM08996.15-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ALM08997.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (907 aa)
ALM09352.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
Your Current Organism:
Sediminicola sp. YIK13
NCBI taxonomy Id: 1453352
Other names: S. sp. YIK13
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