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| | AJR04667.1 | Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa) |
| | dnaJ | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (371 aa) |
| | AJR04644.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa) |
| | AJR04640.1 | Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (667 aa) |
| | AJR04626.1 | Excinuclease ABC subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa) |
| | AJR04625.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | accA | acetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | AJR04596.1 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (513 aa) |
| | thrS | threonyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (644 aa) |
| | dnaA | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (475 aa) |
| | AJR04553.1 | DNA recombination protein RecN; May be involved in recombinational repair of damaged DNA. (550 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (193 aa) |
| | AJR04548.1 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa) |
| | AJR04535.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa) |
| | AJR04453.1 | Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (809 aa) |
| | AJR04452.1 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa) |
| | AJR04445.1 | Clp protease ClpC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (848 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (854 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa) |
| | AJR04409.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa) |
| | AJR04403.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa) |
| | dnaK | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (633 aa) |
| | AJR04365.1 | DEAD/DEAH box helicase; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1037 aa) |
| | AJR04332.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (808 aa) |
| | AJR04324.1 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa) |
| | lon | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (816 aa) |
| | cmk | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa) |
| | AJR04296.1 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (927 aa) |
| | AJR04292.1 | Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (452 aa) |
| | ileS | isoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1134 aa) |
| | AJR02726.1 | 5-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (187 aa) |
| | AJR02724.1 | alpha-L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family. (292 aa) |
| | AJR02723.1 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | AJR02705.1 | FeS assembly SUF system protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa) |
| | sufC | Cysteine desulfurase; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (348 aa) |
| | AJR02694.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (440 aa) |
| | AJR02648.1 | Cell division protein FtsX; Required for cell division and gliding motility. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (292 aa) |
| | leuS | leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (996 aa) |
| | AJR02643.1 | DNA mismatch repair protein MutS; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa) |
| | glyQS | glycyl-tRNA synthetease; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (513 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (538 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (431 aa) |
| | AJR02619.1 | Mrp; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (379 aa) |
| | selO | Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (520 aa) |
| | AJR02570.1 | Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa) |
| | AJR02569.1 | Mevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa) |
| | AJR02531.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa) |
| | AJR02525.1 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (354 aa) |
| | AJR02520.1 | Tetrahydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (424 aa) |
| | AJR02506.1 | Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (384 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa) |
| | AJR02486.1 | Peptidoglycan synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa) |
| | AJR02477.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (368 aa) |
| | argS | arginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa) |
| | ftsH | Peptidase M41; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (647 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (151 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (324 aa) |
| | AJR02420.1 | Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa) |
| | AJR04709.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (209 aa) |
| | AJR02416.1 | Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | AJR02415.1 | ATP-dependent RNA helicase RhlE; This helicase is not essential cell growth; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (431 aa) |
| | AJR02385.1 | Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (870 aa) |
| | lysS | lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (562 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (243 aa) |
| | AJR02304.1 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (487 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (445 aa) |
| | murC | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (450 aa) |
| | AJR04274.1 | Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa) |
| | hisI | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. (197 aa) |
| | AJR04234.1 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa) |
| | AJR04211.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa) |
| | nnrD | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (517 aa) |
| | thrB | Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa) |
| | AJR04186.1 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (787 aa) |
| | recG | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (700 aa) |
| | AJR04179.1 | DNA mismatch repair protein MutS; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (723 aa) |
| | AJR04143.1 | Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa) |
| | AJR04133.1 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (687 aa) |
| | clpB | Clp protease ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (870 aa) |
| | AJR04108.1 | Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa) |
| | AJR04107.1 | Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa) |
| | AJR04106.1 | LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (246 aa) |
| | AJR04103.1 | Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa) |
| | AJR04101.1 | Bacitracin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa) |
| | AJR04100.1 | Nitrate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa) |
| | AJR04082.1 | Heme transporter CcmB; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa) |
| | tilS | Potassium ABC transporter ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (436 aa) |
| | AJR04067.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa) |
| | AJR04045.1 | Lipid kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa) |
| | mnmA | Thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (395 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (511 aa) |
| | AJR04026.1 | DNA topoisomerase IV subunit A; Decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; Derived by automated computational analysis using gene prediction method: Protein Homology. (893 aa) |
| | AJR04025.1 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa) |
| | ychF | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (364 aa) |
| | lolD | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. (221 aa) |
| | AJR04006.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa) |
| | AJR04003.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa) |
| | AJR03986.1 | Galactokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GHMP kinase family. (383 aa) |
| | AJR03973.1 | DNA mismatch repair protein MutS; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa) |
| | AJR03947.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa) |
| | AJR03943.1 | ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa) |
| | AJR03938.1 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | AJR03931.1 | Phosphate starvation protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa) |
| | pckA-2 | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (543 aa) |
| | AJR03898.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa) |
| | AJR03876.1 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa) |
| | hisS | histidyl-tRNA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (817 aa) |
| | AJR03840.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa) |
| | proB-2 | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (256 aa) |
| | AJR03815.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa) |
| | AJR03813.1 | tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa) |
| | AJR03806.1 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (734 aa) |
| | AJR03802.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (198 aa) |
| | AJR03786.1 | Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (816 aa) |
| | AJR03784.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa) |
| | AJR03783.1 | Cell filamentation protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa) |
| | AJR03781.1 | cob(I)yrinic acid a c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa) |
| | secA | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (1117 aa) |
| | AJR03757.1 | ATP-dependent DNA helicase RecQ; Functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa) |
| | AJR03749.1 | Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa) |
| | AJR03710.1 | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa) |
| | AJR03707.1 | Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (620 aa) |
| | recF | DNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (359 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | AJR03682.1 | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (649 aa) |
| | AJR03676.1 | glutamyl-tRNA amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the amidase family. (466 aa) |
| | gatB | aspartyl-tRNA synthetase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (1112 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (878 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (334 aa) |
| | AJR03631.1 | Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa) |
| | accD | Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (285 aa) |
| | AJR03581.1 | Heat shock protein Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. (843 aa) |
| | AJR03580.1 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. (593 aa) |
| | AJR03560.1 | Restriction endonuclease subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1077 aa) |
| | AJR04866.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1421 aa) |
| | dacA | Membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (261 aa) |
| | AJR03534.1 | Antibiotic ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (558 aa) |
| | proS | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (492 aa) |
| | cysS | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (493 aa) |
| | AJR03512.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (615 aa) |
| | AJR03507.1 | Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa) |
| | AJR03506.1 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa) |
| | AJR03492.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa) |
| | AJR03487.1 | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (950 aa) |
| | AJR03473.1 | Antibiotic ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1218 aa) |
| | AJR03458.1 | Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa) |
| | AJR03452.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (791 aa) |
| | AJR03443.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa) |
| | AJR03429.1 | Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa) |
| | AJR03414.1 | Molecular chaperone Hsp90; Molecular chaperone. Has ATPase activity. (635 aa) |
| | AJR03407.1 | RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa) |
| | AJR03363.1 | Cell division protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa) |
| | AJR03358.1 | Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (636 aa) |
| | AJR03347.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa) |
| | groS | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (91 aa) |
| | groEL | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (543 aa) |
| | AJR03335.1 | Rod shape-determining protein MreB; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa) |
| | AJR03329.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (948 aa) |
| | AJR03327.1 | Phosphoenolpyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (964 aa) |
| | AJR03324.1 | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (262 aa) |
| | AJR03318.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa) |
| | AJR03302.1 | Gliding motility protein GldA; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa) |
| | AJR03287.1 | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (415 aa) |
| | AJR03286.1 | Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (253 aa) |
| | AJR03266.1 | Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa) |
| | metK | Hypothetical protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (417 aa) |
| | AJR03254.1 | Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | AJR04802.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (123 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (870 aa) |
| | AJR03215.1 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa) |
| | clpX | ATPase AAA; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (410 aa) |
| | ppnK | Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (294 aa) |
| | AJR03187.1 | Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa) |
| | AJR03185.1 | Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa) |
| | ruvA | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (193 aa) |
| | ruvB | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (340 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa) |
| | asnS | asparaginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (584 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa) |
| | AJR03071.1 | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | AJR03067.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | tdk | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa) |
| | AJR03063.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa) |
| | AJR03047.1 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. (1043 aa) |
| | AJR03037.1 | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (478 aa) |
| | AJR03029.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa) |
| | AJR03026.1 | Aerotolerance regulator BatA; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa) |
| | AJR03025.1 | BatB protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (339 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (195 aa) |
| | AJR02993.1 | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (311 aa) |
| | AJR02992.1 | seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa) |
| | AJR02972.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (416 aa) |
| | AJR02899.1 | glutaminyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (666 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (502 aa) |
| | pgk | Phosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (395 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (423 aa) |
| | AJR02852.1 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa) |
| | atpA | ATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (526 aa) |
| | atpG | ATP F0F1 synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (286 aa) |
| | AJR02830.1 | tryptophanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (322 aa) |
| | recA | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (337 aa) |
| | AJR02816.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (559 aa) |
| | AJR02810.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (688 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1115 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (502 aa) |
