STRINGSTRING
AJR02303.1 AJR02303.1 AJR02587.1 AJR02587.1 AJR02867.1 AJR02867.1 fcl fcl AJR02874.1 AJR02874.1 AJR02983.1 AJR02983.1 AJR03016.1 AJR03016.1 AJR03169.1 AJR03169.1 ilvC ilvC AJR03277.1 AJR03277.1 AJR03281.1 AJR03281.1 AJR03638.1 AJR03638.1 murB murB mdh mdh guaB guaB aroE aroE AJR03888.1 AJR03888.1 AJR03942.1 AJR03942.1 AJR04018.1 AJR04018.1 AJR04054.1 AJR04054.1 AJR04140.1 AJR04140.1 AJR04190.1 AJR04190.1 AJR04199.1 AJR04199.1 AJR04230.1 AJR04230.1 leuB leuB hisD hisD AJR04265.1 AJR04265.1 AJR04284.1 AJR04284.1 AJR04285.1 AJR04285.1 AJR04347.1 AJR04347.1 AJR04460.1 AJR04460.1 AJR04568.1 AJR04568.1 AJR04585.1 AJR04585.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJR02303.1hydroxymethylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family. (440 aa)
AJR02587.1Gluconate 5-dehydrogenase; Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AJR02867.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (467 aa)
fclGDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (348 aa)
AJR02874.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (283 aa)
AJR02983.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
AJR03016.1Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa)
AJR03169.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (763 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa)
AJR03277.13-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (372 aa)
AJR03281.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1133 aa)
AJR03638.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (337 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (306 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
aroEAroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
AJR03888.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
AJR03942.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AJR04018.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
AJR04054.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AJR04140.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
AJR04190.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (276 aa)
AJR04199.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
AJR04230.1Aldehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
AJR04265.13-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
AJR04284.1Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
AJR04285.1UDP-N-acetyl-D-galactosamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (426 aa)
AJR04347.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AJR04460.1Converts D-mannonate to D-mannuronate; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
AJR04568.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (334 aa)
AJR04585.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (737 aa)
Your Current Organism:
Siansivirga zeaxanthinifaciens
NCBI taxonomy Id: 1454006
Other names: S. zeaxanthinifaciens CC-SAMT-1, Siansivirga zeaxanthinifaciens CC-SAMT-1
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