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| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (384 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (160 aa) |
| | AJR02496.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa) |
| | AJR02512.1 | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (543 aa) |
| | pdhA | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (332 aa) |
| | AJR02520.1 | Tetrahydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | AJR02528.1 | Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa) |
| | AJR02597.1 | Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (383 aa) |
| | AJR02610.1 | DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1462 aa) |
| | AJR02631.1 | Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa) |
| | AJR02634.1 | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa) |
| | AJR02667.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa) |
| | AJR02668.1 | Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (348 aa) |
| | AJR02726.1 | 5-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (187 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (502 aa) |
| | AJR02740.1 | ATP synthase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa) |
| | AJR02797.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (346 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (419 aa) |
| | AJR02803.1 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (525 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (341 aa) |
| | AJR02809.1 | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa) |
| | AJR02811.1 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (329 aa) |
| | AJR02815.1 | 3'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa) |
| | AJR02828.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa) |
| | atpG | ATP F0F1 synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (286 aa) |
| | atpA | ATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (526 aa) |
| | atpH | ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa) |
| | atpF | ATP F0F1 synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (166 aa) |
| | AJR02847.1 | ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa) |
| | atpB | ATP synthase F0 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (373 aa) |
| | AJR02859.1 | Uracil phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (423 aa) |
| | AJR02867.1 | UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (467 aa) |
| | fcl | GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (348 aa) |
| | AJR02874.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (283 aa) |
| | AJR02875.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) |
| | AJR02884.1 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa) |
| | AJR02900.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) |
| | AJR02923.1 | GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa) |
| | AJR02944.1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (829 aa) |
| | AJR02946.1 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa) |
| | AJR02958.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (519 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (308 aa) |
| | AJR02983.1 | 2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa) |
| | AJR02993.1 | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (311 aa) |
| | AJR02997.1 | Ribose-phosphate pyrophosphokinase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (195 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa) |
| | AJR03025.1 | BatB protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa) |
| | AJR03026.1 | Aerotolerance regulator BatA; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (365 aa) |
| | AJR03042.1 | Phosphoribosylglycinamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa) |
| | AJR03045.1 | Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (632 aa) |
| | AJR03056.1 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa) |
| | tdk | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa) |
| | AJR03076.1 | 4-hydroxythreonine-4-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PdxA family. (348 aa) |
| | AJR03077.1 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (587 aa) |
| | AJR03122.1 | RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (193 aa) |
| | AJR03132.1 | RNA polymerase sigma54 factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (944 aa) |
| | nusA | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. (410 aa) |
| | queG | Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (306 aa) |
| | AJR03171.1 | SprA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2435 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (297 aa) |
| | ppnK | Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (294 aa) |
| | pdxJ | Pyridoxamine 5'-phosphate oxidase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (237 aa) |
| | AJR03212.1 | RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa) |
| | AJR03214.1 | Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (234 aa) |
| | AJR03215.1 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa) |
| | AJR03242.1 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (274 aa) |
| | AJR03249.1 | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa) |
| | AJR03254.1 | Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (398 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (253 aa) |
| | AJR03289.1 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | AJR03290.1 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa) |
| | AJR03301.1 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa) |
| | queA | S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (349 aa) |
| | AJR03319.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (652 aa) |
| | AJR03324.1 | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (262 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa) |
| | AJR03385.1 | Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa) |
| | AJR03394.1 | DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa) |
| | AJR03399.1 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa) |
| | AJR03425.1 | Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (416 aa) |
| | AJR03437.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa) |
| | AJR03439.1 | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (453 aa) |
| | AJR03458.1 | Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1218 aa) |
| | AJR03472.1 | RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | AJR03478.1 | Glucose-1-phosphate thymidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa) |
| | AJR03485.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa) |
| | AJR03490.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | AJR03498.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa) |
| | AJR03502.1 | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (447 aa) |
| | folE | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (558 aa) |
| | dacA | Membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (261 aa) |
| | AJR03537.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (274 aa) |
| | AJR03587.1 | RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa) |
| | accD | Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (285 aa) |
| | AJR03608.1 | Cobalt transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa) |
| | kmo | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (470 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (423 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (292 aa) |
| | AJR03649.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa) |
| | AJR03654.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa) |
| | AJR03664.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa) |
| | folD | 5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa) |
| | queE | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (209 aa) |
| | AJR03682.1 | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (161 aa) |
| | AJR03710.1 | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa) |
| | AJR03768.1 | RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa) |
| | AJR03781.1 | cob(I)yrinic acid a c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa) |
| | AJR03816.1 | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (303 aa) |
| | proC-2 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa) |
| | proB-2 | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (256 aa) |
| | proA-2 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (399 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (342 aa) |
| | guaB | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (424 aa) |
| | AJR03860.1 | Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (286 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (817 aa) |
| | AJR03873.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (186 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (437 aa) |
| | folE-2 | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa) |
| | AJR03926.1 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | AJR03938.1 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa) |
| | rocD | Ornithine--oxo-acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa) |
| | AJR04002.1 | Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa) |
| | AJR04003.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa) |
| | folE-3 | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa) |
| | serC | MFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (354 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (511 aa) |
| | AJR04034.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | AJR04048.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa) |
| | AJR04052.1 | Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa) |
| | AJR04063.1 | RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | AJR04926.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (229 aa) |
| | AJR04087.1 | Molybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (335 aa) |
| | AJR04088.1 | Molybdopterin-guanine dinucleotide biosynthesis protein MoaC; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | AJR04090.1 | Molybdopterin converting factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa) |
| | AJR04092.1 | Molybdopterin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa) |
| | mobA | Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (197 aa) |
| | AJR04096.1 | Molybdenum cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (392 aa) |
| | pyrB | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (309 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa) |
| | AJR04133.1 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa) |
| | AJR04139.1 | 3-deoxy-manno-octulosonate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsB family. (237 aa) |
| | AJR04144.1 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa) |
| | AJR04189.1 | Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa) |
| | AJR04190.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (276 aa) |
| | AJR04204.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa) |
| | AJR04291.1 | Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa) |
| | AJR04292.1 | Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa) |
| | AJR04295.1 | RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | AJR04304.1 | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa) |
| | AJR04310.1 | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa) |
| | cmk | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa) |
| | AJR04957.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (701 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. (382 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (193 aa) |
| | AJR04555.1 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
| | AJR04556.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa) |
| | AJR04568.1 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (334 aa) |
| | AJR04569.1 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa) |
| | AJR04596.1 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (513 aa) |
| | accA | acetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa) |
| | AJR04622.1 | Cytochrome oxidase assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa) |
| | AJR04663.1 | Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa) |
| | AJR04665.1 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (852 aa) |
| | AJR04667.1 | Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (243 aa) |
| | hemL | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1434 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1270 aa) |
| | nusG | Antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (184 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (261 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (253 aa) |
| | AJR02416.1 | Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (151 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (368 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (330 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (190 aa) |
