(35 nodes) Small molecule sensor activity network (Siansivirga zeaxanthinifaciens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJR04530.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1348 aa)
	AJR02435.1	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (681 aa)
	AJR04545.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1347 aa)
	AJR04548.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
	AJR04678.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
	AJR02603.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (676 aa)
	AJR02624.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
	AJR02643.1	DNA mismatch repair protein MutS; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
	AJR02660.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
	radA	DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (452 aa)
	AJR02778.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
	AJR02796.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
	recA	Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (337 aa)
	AJR04769.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (552 aa)
	AJR03152.1	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (781 aa)
	mutS	DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (870 aa)
	AJR03336.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
	AJR04817.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (626 aa)
	AJR03424.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
	AJR03453.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
	mutL	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (620 aa)
	AJR02338.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
	AJR04893.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1300 aa)
	AJR03770.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
	AJR03973.1	DNA mismatch repair protein MutS; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
	AJR04006.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
	AJR04077.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
	AJR04081.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
	AJR04083.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (826 aa)
	AJR04084.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
	AJR04932.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (461 aa)
	AJR04179.1	DNA mismatch repair protein MutS; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (723 aa)
	AJR02354.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
	AJR04383.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
	AJR04467.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1360 aa)

Your Current Organism:

Siansivirga zeaxanthinifaciens

NCBI taxonomy Id: 1454006
Other names: S. zeaxanthinifaciens CC-SAMT-1, Siansivirga zeaxanthinifaciens CC-SAMT-1

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJR02338.1	AJR03152.1	AW14_00445	AW14_05345	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.426
AJR02338.1	AJR03453.1	AW14_00445	AW14_07245	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
AJR02338.1	AJR04467.1	AW14_00445	AW14_13185	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.564
AJR02338.1	AJR04530.1	AW14_00445	AW14_13685	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.564
AJR02338.1	AJR04545.1	AW14_00445	AW14_13780	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.564
AJR02338.1	AJR04893.1	AW14_00445	AW14_08880	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.529
AJR02338.1	AJR04932.1	AW14_00445	AW14_11400	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.426
AJR02354.1	AJR02660.1	AW14_00575	AW14_02365	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.686
AJR02354.1	AJR03152.1	AW14_00575	AW14_05345	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.652
AJR02354.1	AJR03453.1	AW14_00575	AW14_07245	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.522
AJR02354.1	AJR04083.1	AW14_00575	AW14_10985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.503
AJR02354.1	AJR04467.1	AW14_00575	AW14_13185	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
AJR02354.1	AJR04530.1	AW14_00575	AW14_13685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
AJR02354.1	AJR04545.1	AW14_00575	AW14_13780	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
AJR02354.1	AJR04893.1	AW14_00575	AW14_08880	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.693
AJR02354.1	AJR04932.1	AW14_00575	AW14_11400	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.652
AJR02435.1	AJR03152.1	AW14_01050	AW14_05345	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
AJR02435.1	AJR03424.1	AW14_01050	AW14_07070	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.779
AJR02435.1	AJR04081.1	AW14_01050	AW14_10975	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.429
AJR02435.1	AJR04083.1	AW14_01050	AW14_10985	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.689