(27 nodes) Histidine kinase/HSP90-like ATPase superfamily network (Siansivirga zeaxanthinifaciens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJR02338.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
	AJR02435.1	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (681 aa)
	AJR02603.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (676 aa)
	AJR02624.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
	AJR02660.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
	AJR02778.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
	AJR02796.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
	AJR04769.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (552 aa)
	AJR03152.1	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (781 aa)
	AJR03336.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
	AJR04817.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (626 aa)
	AJR03414.1	Molecular chaperone Hsp90; Molecular chaperone. Has ATPase activity. (635 aa)
	AJR03453.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
	gyrB	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (649 aa)
	mutL	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (620 aa)
	AJR04893.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1300 aa)
	AJR04006.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
	AJR04025.1	DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
	AJR04077.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
	AJR04083.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (826 aa)
	AJR04932.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (461 aa)
	AJR04383.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
	AJR04467.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1360 aa)
	AJR04530.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1348 aa)
	AJR04545.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1347 aa)
	AJR04548.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
	AJR04678.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)

Your Current Organism:

Siansivirga zeaxanthinifaciens

NCBI taxonomy Id: 1454006
Other names: S. zeaxanthinifaciens CC-SAMT-1, Siansivirga zeaxanthinifaciens CC-SAMT-1

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJR02338.1	AJR03152.1	AW14_00445	AW14_05345	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.426
AJR02338.1	AJR03453.1	AW14_00445	AW14_07245	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
AJR02338.1	AJR04467.1	AW14_00445	AW14_13185	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.564
AJR02338.1	AJR04530.1	AW14_00445	AW14_13685	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.564
AJR02338.1	AJR04545.1	AW14_00445	AW14_13780	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.564
AJR02338.1	AJR04893.1	AW14_00445	AW14_08880	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.529
AJR02338.1	AJR04932.1	AW14_00445	AW14_11400	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.426
AJR02435.1	AJR03152.1	AW14_01050	AW14_05345	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
AJR02435.1	AJR04083.1	AW14_01050	AW14_10985	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.689
AJR02435.1	AJR04467.1	AW14_01050	AW14_13185	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.499
AJR02435.1	AJR04530.1	AW14_01050	AW14_13685	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.506
AJR02435.1	AJR04545.1	AW14_01050	AW14_13780	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.501
AJR02435.1	AJR04893.1	AW14_01050	AW14_08880	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.594
AJR02603.1	AJR04467.1	AW14_02030	AW14_13185	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.402
AJR02603.1	AJR04530.1	AW14_02030	AW14_13685	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.402
AJR02603.1	AJR04545.1	AW14_02030	AW14_13780	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.402
AJR02603.1	AJR04893.1	AW14_02030	AW14_08880	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.436
AJR02624.1	AJR02778.1	AW14_02170	AW14_03105	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.425
AJR02624.1	AJR03152.1	AW14_02170	AW14_05345	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.603
AJR02624.1	AJR03453.1	AW14_02170	AW14_07245	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.687