STRINGSTRING
AJR02481.1 AJR02481.1 ftsH ftsH rpoC rpoC alaS alaS AJR02725.1 AJR02725.1 msrB msrB AJR02514.1 AJR02514.1 AJR02495.1 AJR02495.1 dnaJ dnaJ tgt tgt thrS thrS AJR04568.1 AJR04568.1 ligA ligA AJR04447.1 AJR04447.1 AJR04324.1 AJR04324.1 AJR04296.1 AJR04296.1 AJR04282.1 AJR04282.1 fabZ fabZ hisD hisD rnz rnz folE-3 folE-3 kduI kduI AJR03985.1 AJR03985.1 AJR03942.1 AJR03942.1 folE-2 folE-2 priA priA pepT pepT AJR03805.1 AJR03805.1 AJR03592.1 AJR03592.1 AJR03586.1 AJR03586.1 folE folE cysS cysS AJR03517.1 AJR03517.1 hutI hutI AJR03438.1 AJR03438.1 recR recR AJR03405.1 AJR03405.1 AJR03400.1 AJR03400.1 AJR03399.1 AJR03399.1 dnaG dnaG rsgA rsgA AJR04807.1 AJR04807.1 AJR03294.1 AJR03294.1 clpX clpX tadA tadA AJR03056.1 AJR03056.1 AJR03021.1 AJR03021.1 AJR02952.1 AJR02952.1 ybeY ybeY metG metG AJR02762.1 AJR02762.1 radA radA ileS ileS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJR02481.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0758 family. (232 aa)
ftsHPeptidase M41; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (647 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1434 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (870 aa)
AJR02725.1Succinylglutamate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
msrBPilB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MsrB Met sulfoxide reductase family. (153 aa)
AJR02514.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (160 aa)
AJR02495.1Peptidase M3; Derived by automated computational analysis using gene prediction method: Protein Homology. (677 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (371 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa)
thrSthreonyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (644 aa)
AJR04568.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (334 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (664 aa)
AJR04447.1Peptidase M48; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
AJR04324.1Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa)
AJR04296.1Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (927 aa)
AJR04282.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (355 aa)
fabZhydroxymyristoyl-ACP dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (468 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (301 aa)
folE-3GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
kduI5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (280 aa)
AJR03985.1Galactose-1-phosphate uridylyltransferase; Catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AJR03942.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
folE-2GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (817 aa)
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (411 aa)
AJR03805.1D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily. (321 aa)
AJR03592.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
AJR03586.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa)
folEGTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (493 aa)
AJR03517.1Peptidase M48; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
hutIImidazolonepropionase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
AJR03438.1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (189 aa)
recRRecombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (205 aa)
AJR03405.1Peptidase M15; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (221 aa)
AJR03400.1Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
AJR03399.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (652 aa)
rsgAGTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (316 aa)
AJR04807.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (894 aa)
AJR03294.15-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
clpXATPase AAA; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (410 aa)
tadACMP deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (149 aa)
AJR03056.16-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
AJR03021.1Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (208 aa)
AJR02952.1CMP deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
ybeYrRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (136 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (688 aa)
AJR02762.1Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (452 aa)
ileSisoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1134 aa)
Your Current Organism:
Siansivirga zeaxanthinifaciens
NCBI taxonomy Id: 1454006
Other names: S. zeaxanthinifaciens CC-SAMT-1, Siansivirga zeaxanthinifaciens CC-SAMT-1
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