STRINGSTRING
NMS_0124 NMS_0124 folD folD carA carA rpoA rpoA coaD coaD pyrE pyrE trpD trpD NMS_0286 NMS_0286 trpF trpF trpB trpB trpA trpA NMS_0328 NMS_0328 NMS_0331 NMS_0331 dnaG dnaG NMS_0339 NMS_0339 queA queA NMS_0366 NMS_0366 NMS_0375 NMS_0375 NMS_0377 NMS_0377 NMS_0427 NMS_0427 NMS_0431 NMS_0431 NMS_0441 NMS_0441 NMS_0444 NMS_0444 NMS_0453 NMS_0453 NMS_0477 NMS_0477 thyA thyA NMS_0498 NMS_0498 NMS_0504 NMS_0504 pyrH pyrH NMS_0519 NMS_0519 hemH hemH purN purN dinB dinB NMS_0596 NMS_0596 NMS_0608 NMS_0608 NMS_0609 NMS_0609 hemE hemE NMS_0613 NMS_0613 gmk gmk nadD nadD NMS_0643 NMS_0643 NMS_0644 NMS_0644 ctaB ctaB NMS_0675 NMS_0675 NMS_0676 NMS_0676 NMS_0712 NMS_0712 atpD atpD dut dut NMS_0753 NMS_0753 atpB atpB NMS_0772 NMS_0772 atpF atpF atpH atpH atpA atpA atpG atpG tdk tdk NMS_0793 NMS_0793 NMS_0815 NMS_0815 NMS_0822 NMS_0822 NMS_0836 NMS_0836 NMS_0846 NMS_0846 NMS_0847 NMS_0847 purD purD NMS_0901 NMS_0901 NMS_0909 NMS_0909 NMS_0911 NMS_0911 NMS_0918 NMS_0918 hemA hemA thiL thiL pdxJ pdxJ nadK nadK NMS_1055 NMS_1055 NMS_1057 NMS_1057 dxs dxs NMS_1098 NMS_1098 polA polA nusA nusA NMS_1132 NMS_1132 NMS_1143 NMS_1143 NMS_1146 NMS_1146 NMS_1164 NMS_1164 NMS_1170 NMS_1170 accD accD NMS_1315 NMS_1315 kmo kmo kynU kynU NMS_1344 NMS_1344 NMS_1386 NMS_1386 NMS_1401 NMS_1401 purH purH coaX coaX pdhA pdhA NMS_1451 NMS_1451 purK purK adk adk nusG nusG rpoB rpoB rpoC rpoC NMS_1485 NMS_1485 queE queE folE folE rho rho dacA dacA NMS_1547 NMS_1547 NMS_1556 NMS_1556 NMS_1564 NMS_1564 aroQ aroQ pyrD pyrD hemL hemL NMS_1677 NMS_1677 NMS_1697 NMS_1697 NMS_1762 NMS_1762 NMS_1803 NMS_1803 NMS_1807 NMS_1807 NMS_1858 NMS_1858 NMS_1872 NMS_1872 NMS_1873 NMS_1873 coaE coaE NMS_1894 NMS_1894 NMS_1901 NMS_1901 NMS_1930 NMS_1930 purE purE ackA ackA NMS_1973 NMS_1973 NMS_2006 NMS_2006 NMS_2067 NMS_2067 NMS_2074 NMS_2074 NMS_2111 NMS_2111 NMS_2150 NMS_2150 NMS_2170 NMS_2170 NMS_2196 NMS_2196 purA purA NMS_2202 NMS_2202 NMS_2226 NMS_2226 ndk ndk aroC aroC purC purC NMS_2329 NMS_2329 purL purL NMS_2380 NMS_2380 NMS_2392 NMS_2392 NMS_2430 NMS_2430 murA murA NMS_2461 NMS_2461 priA priA NMS_2479 NMS_2479 NMS_2481 NMS_2481 serC serC folE-2 folE-2 NMS_2505 NMS_2505 NMS_2506 NMS_2506 NMS_2511 NMS_2511 NMS_2514 NMS_2514 NMS_2564 NMS_2564 NMS_2574 NMS_2574 pyrB pyrB cmk cmk NMS_2589 NMS_2589 NMS_2606 NMS_2606 NMS_2642 NMS_2642 kdsB kdsB dnaX dnaX pdxH pdxH NMS_2672 NMS_2672 NMS_2694 NMS_2694 fcl fcl NMS_2743 NMS_2743 NMS_2746 NMS_2746 NMS_2757 NMS_2757 pyrG pyrG guaA guaA NMS_0028 NMS_0028 apt apt NMS_0064 NMS_0064 NMS_0102 NMS_0102 NMS_0104 NMS_0104 accA accA tgt tgt aroK aroK
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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NMS_0124Spheroidene monooxygenase. (235 aa)
folDMethylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (372 aa)
rpoADNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (317 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (150 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (201 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa)
NMS_0286Indole-3-glycerol phosphate synthase. (267 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (212 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (388 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa)
NMS_0328Putative cytoplasmic protein. (80 aa)
NMS_0331NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (262 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (652 aa)
NMS_0339RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
queAtRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (350 aa)
NMS_03665-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (414 aa)
NMS_0375Prephenate and/or arogenate dehydrogenase. (286 aa)
NMS_0377Prephenate dehydratase. (270 aa)
NMS_0427DNA polymerase III alpha subunit. (1451 aa)
NMS_0431Ribonucleotide reductase of class Ia (aerobic), alpha subunit. (594 aa)
NMS_0441Ribose-phosphate pyrophosphokinase. (313 aa)
NMS_0444Riboflavin kinase; Belongs to the ribF family. (309 aa)
NMS_0453D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
NMS_04775-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (175 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (274 aa)
NMS_0498Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa)
NMS_0504Deoxyadenosine kinase. (205 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa)
NMS_0519RNA polymerase sigma-54 factor RpoN. (461 aa)
hemHFerrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (350 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (187 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (361 aa)
NMS_0596Amidophosphoribosyltransferase. (632 aa)
NMS_0608Queuosine biosynthesis QueD, PTPS-I. (150 aa)
NMS_0609Coproporphyrinogen III oxidase, aerobic. (303 aa)
hemEUroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (339 aa)
NMS_0613uroporphyrinogen-III synthase, divergent, Flavobacterial type. (153 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (193 aa)
NMS_0643Putative preQ0 transporter; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (181 aa)
NMS_06442-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (349 aa)
ctaBHeme O synthase, protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (297 aa)
NMS_0675Ribosylnicotinamide kinase. (516 aa)
NMS_0676Ribosylnicotinamide kinase. (185 aa)
NMS_0712ATP synthase epsilon chain. (91 aa)
atpDATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (502 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
NMS_0753RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
atpBATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (397 aa)
NMS_0772ATP synthase C chain. (62 aa)
atpFATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa)
atpHATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (182 aa)
atpAATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (524 aa)
atpGATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (290 aa)
tdkThymidine kinase. (212 aa)
NMS_07934-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (351 aa)
NMS_0815ElaA protein. (147 aa)
NMS_0822Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (108 aa)
NMS_0836DNA polymerase III delta prime subunit. (375 aa)
NMS_0846dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (280 aa)
NMS_0847Methyltransferase, FkbM family domain protein. (295 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
NMS_0901Porphobilinogen synthase; Belongs to the ALAD family. (324 aa)
NMS_0909Bacteroides aerotolerance protein BatA. (337 aa)
NMS_0911Bacteroides aerotolerance protein BatB. (342 aa)
NMS_0918Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (314 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (421 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (347 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (237 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (291 aa)
NMS_1055Error-prone repair homolog of DNA polymerase III alpha subunit. (1033 aa)
NMS_1057DNA polymerase IV; Belongs to the DNA polymerase type-Y family. (384 aa)
dxs1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (588 aa)
NMS_1098Dihydrofolate reductase. (308 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (945 aa)
nusATranscription termination protein NusA; Participates in both transcription termination and antitermination. (410 aa)
NMS_1132Hypothetical protein. (2399 aa)
NMS_1143uroporphyrinogen-III synthase HemD, putative. (247 aa)
NMS_1146Dihydroorotase. (446 aa)
NMS_1164Hypothetical radical SAM family enzyme, NOT coproporphyrinogen III oxidase, oxygen-independent; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (353 aa)
NMS_1170TPR repeat precursor. (245 aa)
accDAcetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (286 aa)
NMS_1315ApaG protein. (128 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (464 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (420 aa)
NMS_1344Dihydrofolate synthase. (390 aa)
NMS_1386RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa)
NMS_1401Hypothetical protein. (242 aa)
purHIMP cyclohydrolase. (515 aa)
coaXPantothenate kinase type III, CoaX-like; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (241 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (332 aa)
NMS_1451Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (564 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (367 aa)
nusGTranscription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (184 aa)
rpoBDNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1269 aa)
rpoCDNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1435 aa)
NMS_14856-pyruvoyl tetrahydrobiopterin synthase. (120 aa)
queEQueuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (209 aa)
folEGTP cyclohydrolase I. (223 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (597 aa)
dacADiadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (258 aa)
NMS_1547Dihydropteroate synthase. (258 aa)
NMS_1556Transcription termination protein NusB. (341 aa)
NMS_1564Hypothetical protein PA1329. (132 aa)
aroQ3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (368 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (430 aa)
NMS_1677Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (441 aa)
NMS_1697Competence/damage-inducible protein CinA; Belongs to the CinA family. (418 aa)
NMS_1762Cob(I)alamin adenosyltransferase PduO; Belongs to the Cob(I)alamin adenosyltransferase family. (189 aa)
NMS_1803Orotidine 5'-phosphate decarboxylase. (271 aa)
NMS_1807Phosphoribosylformylglycinamidine cyclo-ligase. (392 aa)
NMS_1858Pyridoxamine 5'-phosphate oxidase. (182 aa)
NMS_1872Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (107 aa)
NMS_1873Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)
NMS_1894Magnesium chelatase, subunit ChlI. (487 aa)
NMS_1901Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (444 aa)
NMS_1930Probable RNA polymerase sigma factor HI1459; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)
NMS_1973Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (699 aa)
NMS_2006Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
NMS_2067RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)
NMS_2074RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa)
NMS_2111Gll1843 protein. (355 aa)
NMS_2150DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (371 aa)
NMS_2170Glucose-1-phosphate thymidylyltransferase. (390 aa)
NMS_2196Shikimate 5-dehydrogenase I alpha. (264 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
NMS_2202Ketosteroid isomerase-related protein. (156 aa)
NMS_22263-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (357 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (318 aa)
NMS_2329Thiamin-phosphate pyrophosphorylase. (210 aa)
purLPhosphoribosylformylglycinamidine synthase, synthetase subunit; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1229 aa)
NMS_2380RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (148 aa)
NMS_2392DNA polymerase III epsilon subunit. (454 aa)
NMS_2430Pterin-4-alpha-carbinolamine dehydratase. (95 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (436 aa)
NMS_2461Transcriptional regulator, ArsR family; Belongs to the UPF0301 (AlgH) family. (194 aa)
priAHelicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (816 aa)
NMS_2479Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family. (288 aa)
NMS_2481Uridine kinase. (202 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (353 aa)
folE-2GTP cyclohydrolase I. (198 aa)
NMS_2505Hypothetical protein. (633 aa)
NMS_2506Dihydroorotase. (419 aa)
NMS_2511Nicotinamide mononucleotide adenylyltransferase. (486 aa)
NMS_2514RNA polymerase sigma-70 factor, ECF subfamily. (179 aa)
NMS_2564Hypothetical protein. (208 aa)
NMS_2574Hypothetical protein. (171 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa)
cmkCytidylate kinase. (229 aa)
NMS_2589RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa)
NMS_2606Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA. (344 aa)
NMS_2642RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (244 aa)
dnaXDNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (602 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa)
NMS_2672Hypothetical protein. (270 aa)
NMS_2694DNA polymerase III delta subunit. (335 aa)
fclGDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (316 aa)
NMS_2743dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
NMS_2746UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (464 aa)
NMS_2757RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (550 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (509 aa)
NMS_0028RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (157 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (173 aa)
NMS_0064Hypothetical protein. (573 aa)
NMS_0102DNA polymerase III epsilon subunit. (466 aa)
NMS_0104Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (516 aa)
accAAcetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (381 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa)
Your Current Organism:
Nonlabens marinus
NCBI taxonomy Id: 1454201
Other names: Flavobacteria bacterium S1-08, N. marinus S1-08, Nonlabens marinus S1-08
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