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NMS_0124 | Spheroidene monooxygenase. (235 aa) | ||||
folD | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa) | ||||
carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (372 aa) | ||||
rpoA | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (317 aa) | ||||
coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (150 aa) | ||||
pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (201 aa) | ||||
trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa) | ||||
NMS_0286 | Indole-3-glycerol phosphate synthase. (267 aa) | ||||
trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (212 aa) | ||||
trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (388 aa) | ||||
trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa) | ||||
NMS_0328 | Putative cytoplasmic protein. (80 aa) | ||||
NMS_0331 | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (262 aa) | ||||
dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (652 aa) | ||||
NMS_0339 | RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa) | ||||
queA | tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (350 aa) | ||||
NMS_0366 | 5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (414 aa) | ||||
NMS_0375 | Prephenate and/or arogenate dehydrogenase. (286 aa) | ||||
NMS_0377 | Prephenate dehydratase. (270 aa) | ||||
NMS_0427 | DNA polymerase III alpha subunit. (1451 aa) | ||||
NMS_0431 | Ribonucleotide reductase of class Ia (aerobic), alpha subunit. (594 aa) | ||||
NMS_0441 | Ribose-phosphate pyrophosphokinase. (313 aa) | ||||
NMS_0444 | Riboflavin kinase; Belongs to the ribF family. (309 aa) | ||||
NMS_0453 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa) | ||||
NMS_0477 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (175 aa) | ||||
thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (274 aa) | ||||
NMS_0498 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa) | ||||
NMS_0504 | Deoxyadenosine kinase. (205 aa) | ||||
pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa) | ||||
NMS_0519 | RNA polymerase sigma-54 factor RpoN. (461 aa) | ||||
hemH | Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (350 aa) | ||||
purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (187 aa) | ||||
dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (361 aa) | ||||
NMS_0596 | Amidophosphoribosyltransferase. (632 aa) | ||||
NMS_0608 | Queuosine biosynthesis QueD, PTPS-I. (150 aa) | ||||
NMS_0609 | Coproporphyrinogen III oxidase, aerobic. (303 aa) | ||||
hemE | Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (339 aa) | ||||
NMS_0613 | uroporphyrinogen-III synthase, divergent, Flavobacterial type. (153 aa) | ||||
gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa) | ||||
nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (193 aa) | ||||
NMS_0643 | Putative preQ0 transporter; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (181 aa) | ||||
NMS_0644 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (349 aa) | ||||
ctaB | Heme O synthase, protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (297 aa) | ||||
NMS_0675 | Ribosylnicotinamide kinase. (516 aa) | ||||
NMS_0676 | Ribosylnicotinamide kinase. (185 aa) | ||||
NMS_0712 | ATP synthase epsilon chain. (91 aa) | ||||
atpD | ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (502 aa) | ||||
dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa) | ||||
NMS_0753 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa) | ||||
atpB | ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (397 aa) | ||||
NMS_0772 | ATP synthase C chain. (62 aa) | ||||
atpF | ATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) | ||||
atpH | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (182 aa) | ||||
atpA | ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (524 aa) | ||||
atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (290 aa) | ||||
tdk | Thymidine kinase. (212 aa) | ||||
NMS_0793 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (351 aa) | ||||
NMS_0815 | ElaA protein. (147 aa) | ||||
NMS_0822 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (108 aa) | ||||
NMS_0836 | DNA polymerase III delta prime subunit. (375 aa) | ||||
NMS_0846 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (280 aa) | ||||
NMS_0847 | Methyltransferase, FkbM family domain protein. (295 aa) | ||||
purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa) | ||||
NMS_0901 | Porphobilinogen synthase; Belongs to the ALAD family. (324 aa) | ||||
NMS_0909 | Bacteroides aerotolerance protein BatA. (337 aa) | ||||
NMS_0911 | Bacteroides aerotolerance protein BatB. (342 aa) | ||||
NMS_0918 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (314 aa) | ||||
hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (421 aa) | ||||
thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (347 aa) | ||||
pdxJ | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (237 aa) | ||||
nadK | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (291 aa) | ||||
NMS_1055 | Error-prone repair homolog of DNA polymerase III alpha subunit. (1033 aa) | ||||
NMS_1057 | DNA polymerase IV; Belongs to the DNA polymerase type-Y family. (384 aa) | ||||
dxs | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (588 aa) | ||||
NMS_1098 | Dihydrofolate reductase. (308 aa) | ||||
polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (945 aa) | ||||
nusA | Transcription termination protein NusA; Participates in both transcription termination and antitermination. (410 aa) | ||||
NMS_1132 | Hypothetical protein. (2399 aa) | ||||
NMS_1143 | uroporphyrinogen-III synthase HemD, putative. (247 aa) | ||||
NMS_1146 | Dihydroorotase. (446 aa) | ||||
NMS_1164 | Hypothetical radical SAM family enzyme, NOT coproporphyrinogen III oxidase, oxygen-independent; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (353 aa) | ||||
NMS_1170 | TPR repeat precursor. (245 aa) | ||||
accD | Acetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (286 aa) | ||||
NMS_1315 | ApaG protein. (128 aa) | ||||
kmo | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (464 aa) | ||||
kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (420 aa) | ||||
NMS_1344 | Dihydrofolate synthase. (390 aa) | ||||
NMS_1386 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa) | ||||
NMS_1401 | Hypothetical protein. (242 aa) | ||||
purH | IMP cyclohydrolase. (515 aa) | ||||
coaX | Pantothenate kinase type III, CoaX-like; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (241 aa) | ||||
pdhA | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (332 aa) | ||||
NMS_1451 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (564 aa) | ||||
purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) | ||||
adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (367 aa) | ||||
nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (184 aa) | ||||
rpoB | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1269 aa) | ||||
rpoC | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1435 aa) | ||||
NMS_1485 | 6-pyruvoyl tetrahydrobiopterin synthase. (120 aa) | ||||
queE | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (209 aa) | ||||
folE | GTP cyclohydrolase I. (223 aa) | ||||
rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (597 aa) | ||||
dacA | Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (258 aa) | ||||
NMS_1547 | Dihydropteroate synthase. (258 aa) | ||||
NMS_1556 | Transcription termination protein NusB. (341 aa) | ||||
NMS_1564 | Hypothetical protein PA1329. (132 aa) | ||||
aroQ | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) | ||||
pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (368 aa) | ||||
hemL | Glutamate-1-semialdehyde aminotransferase. (430 aa) | ||||
NMS_1677 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (441 aa) | ||||
NMS_1697 | Competence/damage-inducible protein CinA; Belongs to the CinA family. (418 aa) | ||||
NMS_1762 | Cob(I)alamin adenosyltransferase PduO; Belongs to the Cob(I)alamin adenosyltransferase family. (189 aa) | ||||
NMS_1803 | Orotidine 5'-phosphate decarboxylase. (271 aa) | ||||
NMS_1807 | Phosphoribosylformylglycinamidine cyclo-ligase. (392 aa) | ||||
NMS_1858 | Pyridoxamine 5'-phosphate oxidase. (182 aa) | ||||
NMS_1872 | Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (107 aa) | ||||
NMS_1873 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa) | ||||
coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa) | ||||
NMS_1894 | Magnesium chelatase, subunit ChlI. (487 aa) | ||||
NMS_1901 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (444 aa) | ||||
NMS_1930 | Probable RNA polymerase sigma factor HI1459; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa) | ||||
purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa) | ||||
ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) | ||||
NMS_1973 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (699 aa) | ||||
NMS_2006 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa) | ||||
NMS_2067 | RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa) | ||||
NMS_2074 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa) | ||||
NMS_2111 | Gll1843 protein. (355 aa) | ||||
NMS_2150 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (371 aa) | ||||
NMS_2170 | Glucose-1-phosphate thymidylyltransferase. (390 aa) | ||||
NMS_2196 | Shikimate 5-dehydrogenase I alpha. (264 aa) | ||||
purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa) | ||||
NMS_2202 | Ketosteroid isomerase-related protein. (156 aa) | ||||
NMS_2226 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (357 aa) | ||||
ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) | ||||
purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (318 aa) | ||||
NMS_2329 | Thiamin-phosphate pyrophosphorylase. (210 aa) | ||||
purL | Phosphoribosylformylglycinamidine synthase, synthetase subunit; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1229 aa) | ||||
NMS_2380 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (148 aa) | ||||
NMS_2392 | DNA polymerase III epsilon subunit. (454 aa) | ||||
NMS_2430 | Pterin-4-alpha-carbinolamine dehydratase. (95 aa) | ||||
murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (436 aa) | ||||
NMS_2461 | Transcriptional regulator, ArsR family; Belongs to the UPF0301 (AlgH) family. (194 aa) | ||||
priA | Helicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (816 aa) | ||||
NMS_2479 | Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family. (288 aa) | ||||
NMS_2481 | Uridine kinase. (202 aa) | ||||
serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (353 aa) | ||||
folE-2 | GTP cyclohydrolase I. (198 aa) | ||||
NMS_2505 | Hypothetical protein. (633 aa) | ||||
NMS_2506 | Dihydroorotase. (419 aa) | ||||
NMS_2511 | Nicotinamide mononucleotide adenylyltransferase. (486 aa) | ||||
NMS_2514 | RNA polymerase sigma-70 factor, ECF subfamily. (179 aa) | ||||
NMS_2564 | Hypothetical protein. (208 aa) | ||||
NMS_2574 | Hypothetical protein. (171 aa) | ||||
pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa) | ||||
cmk | Cytidylate kinase. (229 aa) | ||||
NMS_2589 | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa) | ||||
NMS_2606 | Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA. (344 aa) | ||||
NMS_2642 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa) | ||||
kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (244 aa) | ||||
dnaX | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (602 aa) | ||||
pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa) | ||||
NMS_2672 | Hypothetical protein. (270 aa) | ||||
NMS_2694 | DNA polymerase III delta subunit. (335 aa) | ||||
fcl | GDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (316 aa) | ||||
NMS_2743 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) | ||||
NMS_2746 | UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (464 aa) | ||||
NMS_2757 | RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa) | ||||
pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (550 aa) | ||||
guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (509 aa) | ||||
NMS_0028 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (157 aa) | ||||
apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (173 aa) | ||||
NMS_0064 | Hypothetical protein. (573 aa) | ||||
NMS_0102 | DNA polymerase III epsilon subunit. (466 aa) | ||||
NMS_0104 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (516 aa) | ||||
accA | Acetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) | ||||
tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (381 aa) | ||||
aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa) |