(16 nodes) Lysine degradation network (Nonlabens marinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NMS_1644	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (456 aa)
	NMS_0176	Lysine ketoglutarate reductase. (410 aa)
	NMS_0542	glutaryl-CoA dehydrogenase. (392 aa)
	NMS_0622	Aldehyde dehydrogenase B; Belongs to the aldehyde dehydrogenase family. (517 aa)
	NMS_1093	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (444 aa)
	NMS_1140	Saccharopine dehydrogenase. (454 aa)
	NMS_1158	Succinate-semialdehyde dehydrogenase. (461 aa)
	NMS_1159	glutaryl-CoA dehydrogenase. (454 aa)
	NMS_1254	Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (467 aa)
	NMS_1498	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (451 aa)
	NMS_1608	Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase. (463 aa)
	NMS_2154	Succinate-semialdehyde dehydrogenase. (452 aa)
	NMS_2373	Mll7640 protein. (200 aa)
	NMS_2446	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (457 aa)
	NMS_2665	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	NMS_2755	Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (466 aa)

Your Current Organism:

Nonlabens marinus

NCBI taxonomy Id: 1454201
Other names: Flavobacteria bacterium S1-08, N. marinus S1-08, Nonlabens marinus S1-08

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
NMS_0176	NMS_1140	Lysine ketoglutarate reductase.	Saccharopine dehydrogenase.	0.984
NMS_0542	NMS_1093	glutaryl-CoA dehydrogenase.	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.900
NMS_0542	NMS_1159	glutaryl-CoA dehydrogenase.	glutaryl-CoA dehydrogenase.	0.903
NMS_0542	NMS_1254	glutaryl-CoA dehydrogenase.	Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.	0.623
NMS_0542	NMS_1498	glutaryl-CoA dehydrogenase.	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.	0.700
NMS_0542	NMS_1608	glutaryl-CoA dehydrogenase.	Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.	0.891
NMS_0542	NMS_1644	glutaryl-CoA dehydrogenase.	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.	0.700
NMS_0542	NMS_2665	glutaryl-CoA dehydrogenase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610
NMS_0542	NMS_2755	glutaryl-CoA dehydrogenase.	Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.	0.623
NMS_0622	NMS_2446	Aldehyde dehydrogenase B; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.696
NMS_1093	NMS_0542	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	glutaryl-CoA dehydrogenase.	0.900
NMS_1093	NMS_1159	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	glutaryl-CoA dehydrogenase.	0.900
NMS_1093	NMS_1254	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.	0.979
NMS_1093	NMS_1498	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.	0.734
NMS_1093	NMS_1608	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.	0.992
NMS_1093	NMS_1644	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.	0.866
NMS_1093	NMS_2665	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.891
NMS_1093	NMS_2755	Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.	0.981
NMS_1140	NMS_0176	Saccharopine dehydrogenase.	Lysine ketoglutarate reductase.	0.984
NMS_1158	NMS_1159	Succinate-semialdehyde dehydrogenase.	glutaryl-CoA dehydrogenase.	0.609