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metK metK thrB thrB SRAA_0682 SRAA_0682 thrA thrA thrC thrC SRAA_0903 SRAA_0903 metE metE metZ metZ SRAA_1961 SRAA_1961 SRAA_1969 SRAA_1969 ahcY ahcY SRAA_2360 SRAA_2360
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (393 aa)
thrBPutative homoserine kinase type II; Identified by MetaGeneAnnotator; putative; protein kinase fold; Belongs to the pseudomonas-type ThrB family. (318 aa)
SRAA_0682Cystathionine beta-lyase/cystathionine gamma-synthase; Identified by MetaGeneAnnotator; putative. (415 aa)
thrAHomoserine dehydrogenase; Identified by MetaGeneAnnotator; putative. (453 aa)
thrCThreonine synthase; Identified by MetaGeneAnnotator; putative. (476 aa)
SRAA_0903O-acetylhomoserine sulfhydrylase; Identified by MetaGeneAnnotator; putative. (433 aa)
metEMethionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (783 aa)
metZCystathionine beta-lyase/cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (410 aa)
SRAA_1961Methionine synthase I, cobalamin-binding domain; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (900 aa)
SRAA_19695,10-methylenetetrahydrofolate reductase; Identified by MetaGeneAnnotator; putative; Belongs to the methylenetetrahydrofolate reductase family. (281 aa)
ahcYS-adenosylhomocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (478 aa)
SRAA_2360Methionine synthase I (cobalamin-dependent), methyltransferase domain; Identified by MetaGeneAnnotator; putative. (350 aa)
Your Current Organism:
Serpentinomonas raichei
NCBI taxonomy Id: 1458425
Other names: Comamonadaceae bacterium A1, Comamonadaceae bacterium H1, S. raichei, strain A1
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