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coaX coaX nadD nadD panC panC panB panB SRAA_0846 SRAA_0846 ppnK ppnK coaD coaD dfp dfp nadB nadB panD panD nadA nadA nadE nadE SRAA_2059 SRAA_2059 SRAA_2343 SRAA_2343 SRAA_2344 SRAA_2344 SRAA_2345 SRAA_2345 SRAA_2346 SRAA_2346
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
coaXPutative transcriptional regulator, homolog of Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (266 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (229 aa)
panCPanthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (299 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (291 aa)
SRAA_0846Nicotinate-nucleotide pyrophosphorylase; Identified by MetaGeneAnnotator; putative; Belongs to the NadC/ModD family. (291 aa)
ppnKPredicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (296 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (182 aa)
dfpPhosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (405 aa)
nadBAspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (544 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (380 aa)
nadENAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (581 aa)
SRAA_2059Uncharacterized protein; Competence- and mitomycin-induced; identified by MetaGeneAnnotator; putative; Belongs to the CinA family. (167 aa)
SRAA_2343NAD/NADP transhydrogenase alpha subunit; Identified by MetaGeneAnnotator; putative. (378 aa)
SRAA_2344NAD/NADP transhydrogenase alpha subunit; Identified by MetaGeneAnnotator; putative. (108 aa)
SRAA_2345NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (477 aa)
SRAA_2346Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative. (115 aa)
Your Current Organism:
Serpentinomonas raichei
NCBI taxonomy Id: 1458425
Other names: Comamonadaceae bacterium A1, Comamonadaceae bacterium H1, S. raichei, strain A1
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