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ftsQ ftsQ ddl ddl murC murC murG murG ftsW ftsW murD murD mraY mraY murF murF murE murE ftsI ftsI SRAA_2036 SRAA_2036 topB topB SRAA_2075 SRAA_2075 SRAA_2123 SRAA_2123 SRAA_2135 SRAA_2135 SRAA_2143 SRAA_2143 lptA lptA flhC flhC flhD flhD SRAA_2176 SRAA_2176 minC minC SRAA_2251 SRAA_2251 lptE lptE bamE bamE surA surA lptD lptD SRAA_2340 SRAA_2340 yjgR yjgR SRAA_2373 SRAA_2373 SRAA_0284 SRAA_0284 SRAA_0368 SRAA_0368 SRAA_0386 SRAA_0386 SRAA_0419 SRAA_0419 SRAA_0440 SRAA_0440 murI murI prfA prfA flhA flhA SRAA_0483 SRAA_0483 SRAA_0487 SRAA_0487 SRAA_0488 SRAA_0488 SRAA_0491 SRAA_0491 SRAA_0497 SRAA_0497 SRAA_0498 SRAA_0498 SRAA_0529 SRAA_0529 mfd mfd iscS iscS SRAA_0555 SRAA_0555 SRAA_0556 SRAA_0556 hscB hscB hscA hscA SRAA_0566 SRAA_0566 smc smc SRAA_0622 SRAA_0622 bamD bamD bamB bamB SRAA_0664 SRAA_0664 SRAA_0690 SRAA_0690 frr frr bamA bamA skp skp rsfS rsfS cpoB cpoB SRAA_0805 SRAA_0805 SRAA_0808 SRAA_0808 secB secB rplT rplT SRAA_0926 SRAA_0926 dnaB dnaB SRAA_1022 SRAA_1022 mltG mltG SRAA_1026 SRAA_1026 SRAA_1027 SRAA_1027 SRAA_1139 SRAA_1139 prfB prfB cas1 cas1 SRAA_1197 SRAA_1197 SRAA_1256 SRAA_1256 uppP uppP parE parE SRAA_1292 SRAA_1292 SRAA_0283 SRAA_0283 SRAA_0280 SRAA_0280 SRAA_0272 SRAA_0272 SRAA_0271 SRAA_0271 SRAA_0270 SRAA_0270 SRAA_0268 SRAA_0268 cyaY cyaY SRAA_0265 SRAA_0265 SRAA_0264 SRAA_0264 engB engB SRAA_0196 SRAA_0196 priA priA rep rep zapD zapD glmU glmU pilT pilT SRAA_0023 SRAA_0023 gyrB gyrB SRAA_0285 SRAA_0285 SRAA_0288 SRAA_0288 murA murA SRAA_0341 SRAA_0341 fliQ fliQ fliP fliP SRAA_0344 SRAA_0344 SRAA_0348 SRAA_0348 SRAA_0349 SRAA_0349 SRAA_0350 SRAA_0350 SRAA_0355 SRAA_0355 SRAA_1294 SRAA_1294 parC parC SRAA_1370 SRAA_1370 cas2-2 cas2-2 cas1-2 cas1-2 SRAA_1388 SRAA_1388 SRAA_1390 SRAA_1390 gyrA gyrA SRAA_1443 SRAA_1443 SRAA_1449 SRAA_1449 murB murB SRAA_1535 SRAA_1535 SRAA_1536 SRAA_1536 SRAA_1537 SRAA_1537 SRAA_1539 SRAA_1539 SRAA_1559 SRAA_1559 SRAA_1573 SRAA_1573 SRAA_1611 SRAA_1611 pilB pilB nagZ nagZ murJ murJ ruvB ruvB ruvA ruvA SRAA_1760 SRAA_1760 prfC prfC mrdB mrdB mpl mpl ureE ureE SRAA_1959 SRAA_1959 SRAA_1960 SRAA_1960 erpA erpA mtgA mtgA ftsZ ftsZ
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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ftsQCell division septal protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (276 aa)
ddlD-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (342 aa)
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (486 aa)
murGUDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (361 aa)
ftsWBacterial cell division membrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (445 aa)
murDUDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (635 aa)
mraYUDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (392 aa)
murFUDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (525 aa)
murEUDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (517 aa)
ftsICell division protein FtsI/penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (576 aa)
SRAA_2036Superfamily II DNA/RNA helicase, SNF2 family; Identified by MetaGeneAnnotator; putative. (1129 aa)
topBTopoisomerase IA; Identified by MetaGeneAnnotator; putative. (939 aa)
SRAA_2075ATP-dependent exoDNAse beta subunit; Exonuclease V, contains helicase and exonuclease domains; identified by MetaGeneAnnotator; putative; Belongs to the helicase family. UvrD subfamily. (1177 aa)
SRAA_2123D-alanyl-D-alanine carboxypeptidase; Identified by MetaGeneAnnotator; putative; Belongs to the peptidase S11 family. (396 aa)
SRAA_2135Flagellar basal body protein; Identified by MetaGeneAnnotator; putative. (91 aa)
SRAA_2143Superfamily II DNA helicase; Identified by MetaGeneAnnotator; putative. (657 aa)
lptAUncharacterized protein conserved in bacteria; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (217 aa)
flhCHypothetical protein; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (199 aa)
flhDHypothetical protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (117 aa)
SRAA_2176Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative; Belongs to the Cob(I)alamin adenosyltransferase family. (194 aa)
minCSeptum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (250 aa)
SRAA_2251Membrane-bound lytic murein transglycosylase; Identified by MetaGeneAnnotator; putative. (442 aa)
lptERare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (182 aa)
bamEtmRNA-binding small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (169 aa)
surAParvulin-like peptidyl-prolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (469 aa)
lptDOrganic solvent tolerance protein OstA; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (814 aa)
SRAA_2340Predicted phosphotransferase related to Ser/Thr protein kinase; Identified by MetaGeneAnnotator; putative. (369 aa)
yjgRPredicted ATPase; Identified by MetaGeneAnnotator; putative. (486 aa)
SRAA_2373Uncharacterized conserved protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (87 aa)
SRAA_0284ABC-type transport system involved in resistance to organic solvents, auxiliary component; Identified by MetaGeneAnnotator; putative. (228 aa)
SRAA_0368Superfamily I DNA and RNA helicase; Identified by MetaGeneAnnotator; putative. (802 aa)
SRAA_0386Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (481 aa)
SRAA_0419SWIB-domain-containing protein implicated in chromatin remodeling; Identified by MetaGeneAnnotator; putative. (141 aa)
SRAA_0440Soluble lytic murein transglycosylase and related regulatory protein; Identified by MetaGeneAnnotator; putative; some contain LysM/invasin domains. (319 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (274 aa)
prfAProtein chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (371 aa)
flhAFlagellar biosynthesis pathway, component FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (696 aa)
SRAA_0483Flagellar GTP-binding protein; Identified by MetaGeneAnnotator; putative. (519 aa)
SRAA_0487Negative regulator of flagellin synthesis; Anti-sigma28 factor; identified by MetaGeneAnnotator; putative. (120 aa)
SRAA_0488Flagellar basal body P-ring biosynthesis protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (227 aa)
SRAA_0491Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein. (218 aa)
SRAA_0497Muramidase (flagellum-specific); Identified by MetaGeneAnnotator; putative. (304 aa)
SRAA_0498Flagellar hook-associated protein; Identified by MetaGeneAnnotator; putative; Belongs to the flagella basal body rod proteins family. (631 aa)
SRAA_0529D-alanyl-D-alanine carboxypeptidase; Identified by MetaGeneAnnotator; putative; Belongs to the peptidase S11 family. (422 aa)
mfdTranscription-repair coupling factor, superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1220 aa)
iscSCysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (404 aa)
SRAA_0555nifU homolog involved in Fe-S cluster formation; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (143 aa)
SRAA_0556Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative; Belongs to the HesB/IscA family. (107 aa)
hscBDnaJ-domain-containing protein 1; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (195 aa)
hscAMolecular chaperone; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (634 aa)
SRAA_0566Predicted membrane GTPase involved in stress response; Identified by MetaGeneAnnotator; putative. (608 aa)
smcChromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1207 aa)
SRAA_0622Hypothetical protein; Identified by MetaGeneAnnotator; putative. (359 aa)
bamDDNA uptake lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (251 aa)
bamBHypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (390 aa)
SRAA_0664Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Identified by MetaGeneAnnotator; putative. (815 aa)
SRAA_0690Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; Identified by MetaGeneAnnotator; putative. (161 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (186 aa)
bamAOuter membrane protein/protective antigen OMA87; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (771 aa)
skpOuter membrane protein; Identified by MetaGeneAnnotator; putative; Belongs to the skp family. (174 aa)
rsfSUncharacterized homolog of plant Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (259 aa)
cpoBUncharacterized protein conserved in bacteria; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (275 aa)
SRAA_0805Protein chain release factor B; Identified by MetaGeneAnnotator; putative. (126 aa)
SRAA_0808Flagellin-specific chaperone FliS; Identified by MetaGeneAnnotator; putative. (129 aa)
secBPreprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (155 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (107 aa)
SRAA_0926Protein chain release factor B; Identified by MetaGeneAnnotator; putative. (132 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (470 aa)
SRAA_1022Tfp pilus assembly protein PilZ; Identified by MetaGeneAnnotator; putative. (121 aa)
mltGPredicted periplasmic solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (335 aa)
SRAA_1026Predicted aminomethyltransferase related to GcvT; Identified by MetaGeneAnnotator; putative; Belongs to the GcvT family. (342 aa)
SRAA_1027Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative. (308 aa)
SRAA_1139NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain; Identified by MetaGeneAnnotator; putative. (506 aa)
prfBProtein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (300 aa)
cas1CRISPR/Cas system-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (306 aa)
SRAA_1197Hypothetical protein; Identified by MetaGeneAnnotator; putative. (226 aa)
SRAA_1256Predicted ATPase involved in replication control, Cdc46/Mcm family; Identified by MetaGeneAnnotator; putative. (923 aa)
uppPUncharacterized bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (277 aa)
parEType IIA topoisomerase, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (662 aa)
SRAA_1292Uncharacterized lipoprotein; Identified by MetaGeneAnnotator; putative. (343 aa)
SRAA_0283Surface lipoprotein; Identified by MetaGeneAnnotator; putative. (275 aa)
SRAA_0280ABC-type transport system involved in resistance to organic solvents, ATPase component; Identified by MetaGeneAnnotator; putative. (272 aa)
SRAA_0272Tfp pilus assembly protein PilP; Identified by MetaGeneAnnotator; putative. (182 aa)
SRAA_0271Tfp pilus assembly protein PilO; Identified by MetaGeneAnnotator; putative. (232 aa)
SRAA_0270Tfp pilus assembly protein PilN; Identified by MetaGeneAnnotator; putative. (212 aa)
SRAA_0268Membrane carboxypeptidase/penicillin-binding protein; Identified by MetaGeneAnnotator; putative. (804 aa)
cyaYProtein implicated in iron transport, frataxin homolog; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (111 aa)
SRAA_0265ABC-type transport system involved in cytochrome c biogenesis, permease component; Identified by MetaGeneAnnotator; putative. (464 aa)
SRAA_0264ResB protein required for cytochrome c biosynthesis; Identified by MetaGeneAnnotator; putative. (692 aa)
engBPredicted GTPase; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (230 aa)
SRAA_0196Thiol:disulfide interchange protein; Identified by MetaGeneAnnotator; putative. (727 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (697 aa)
repSuperfamily I DNA and RNA helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (724 aa)
zapDUncharacterized protein conserved in bacteria; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (251 aa)
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (467 aa)
pilTTfp pilus assembly protein, pilus retraction ATPase PilT; Identified by MetaGeneAnnotator; putative. (347 aa)
SRAA_0023RecG-like helicase; Identified by MetaGeneAnnotator; putative. (708 aa)
gyrBType IIA topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (878 aa)
SRAA_0285Predicted NTP binding protein containing STAS domain; Identified by MetaGeneAnnotator; putative. (106 aa)
SRAA_0288Predicted transcriptional regulator, BolA superfamily; Identified by MetaGeneAnnotator; putative; Belongs to the BolA/IbaG family. (103 aa)
murAUDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (428 aa)
SRAA_0341Flagellar biosynthesis pathway, component FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (259 aa)
fliQFlagellar biosynthesis pathway, component FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
fliPFlagellar biosynthesis pathway, component FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (265 aa)
SRAA_0344Flagellar biogenesis protein; Identified by MetaGeneAnnotator; putative. (141 aa)
SRAA_0348Flagellar hook-length control protein; Identified by MetaGeneAnnotator; putative. (416 aa)
SRAA_0349Flagellar biosynthesis chaperone; Identified by MetaGeneAnnotator; putative. (156 aa)
SRAA_0350Flagellar biosynthesis/type III secretory pathway ATPase; Identified by MetaGeneAnnotator; putative. (486 aa)
SRAA_0355Hypothetical protein; Identified by MetaGeneAnnotator; putative. (100 aa)
SRAA_1294ATPase involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (365 aa)
parCType IIA topoisomerase, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (777 aa)
SRAA_1370Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; Identified by MetaGeneAnnotator; putative. (2099 aa)
cas2-2Uncharacterized protein predicted to be involved in DNA repair; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (96 aa)
cas1-2Uncharacterized protein predicted to be involved in DNA repair; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (348 aa)
SRAA_1388Uncharacterized protein predicted to be involved in DNA repair; Identified by MetaGeneAnnotator; putative. (321 aa)
SRAA_1390Hypothetical protein; Identified by MetaGeneAnnotator; putative. (228 aa)
gyrAType IIA topoisomerase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (916 aa)
SRAA_1443Superfamily I DNA and RNA helicase; Identified by MetaGeneAnnotator; putative. (558 aa)
SRAA_1449Superfamily II DNA helicase; Identified by MetaGeneAnnotator; putative. (692 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (358 aa)
SRAA_1535Tfp pilus assembly protein PilV; Identified by MetaGeneAnnotator; putative. (182 aa)
SRAA_1536Tfp pilus assembly protein PilW; Identified by MetaGeneAnnotator; putative. (287 aa)
SRAA_1537Tfp pilus assembly protein PilX; Identified by MetaGeneAnnotator; putative. (180 aa)
SRAA_1539Tfp pilus assembly protein PilE; Identified by MetaGeneAnnotator; putative. (149 aa)
SRAA_1559ABC-type uncharacterized transport system, permease component; Identified by MetaGeneAnnotator; putative. (266 aa)
SRAA_1573Soluble lytic murein transglycosylase and related regulatory protein; Identified by MetaGeneAnnotator; putative; some contain LysM/invasin domains. (300 aa)
SRAA_1611Soluble lytic murein transglycosylase and related regulatory protein; Identified by MetaGeneAnnotator; putative; some contain LysM/invasin domains. (209 aa)
pilBType II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Identified by MetaGeneAnnotator; putative. (576 aa)
nagZBeta-glucosidase-related glycosidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (385 aa)
murJUncharacterized membrane protein, putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (521 aa)
ruvBHolliday junction resolvasome, helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa)
ruvAHolliday junction resolvasome, DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (194 aa)
SRAA_1760Cell division protein FtsI/penicillin-binding protein 2; Identified by MetaGeneAnnotator; putative. (648 aa)
prfCPeptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (539 aa)
mrdBBacterial cell division membrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (385 aa)
mplUDP-N-acetylmuramate-alanine ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (491 aa)
ureEUrease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (175 aa)
SRAA_1959Predicted ATPase with chaperone activity; Identified by MetaGeneAnnotator; putative. (517 aa)
SRAA_1960Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Identified by MetaGeneAnnotator; putative. (847 aa)
erpAUncharacterized conserved protein; Required for insertion of 4Fe-4S clusters. (121 aa)
mtgAMembrane carboxypeptidase, penicillin-binding protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (243 aa)
ftsZCell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (414 aa)
Your Current Organism:
Serpentinomonas raichei
NCBI taxonomy Id: 1458425
Other names: Comamonadaceae bacterium A1, Comamonadaceae bacterium H1, S. raichei, strain A1
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