Your Input: | |
| | rpoA | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (328 aa) |
| | SRAA_0095 | Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative. (135 aa) |
| | vapC | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (141 aa) |
| | vapC-2 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (134 aa) |
| | vapC-3 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (148 aa) |
| | SRAA_0151 | Serine/threonine protein phosphatase; Identified by MetaGeneAnnotator; putative. (92 aa) |
| | SRAA_0152 | tRNA and rRNA cytosine-C5-methylase; Identified by MetaGeneAnnotator; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (485 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (333 aa) |
| | SRAA_0184 | Cytotoxic translational repressor of toxin-antitoxin stability system; Identified by MetaGeneAnnotator; putative. (79 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (697 aa) |
| | SRAA_0200 | tRNA and rRNA cytosine-C5-methylase; Identified by MetaGeneAnnotator; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (480 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1403 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1372 aa) |
| | SRAA_0208 | Uncharacterized protein conserved in bacteria; Identified by MetaGeneAnnotator; putative. (70 aa) |
| | lysS | lysyl-tRNA synthetase class II; Identified by MetaGeneAnnotator; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. (515 aa) |
| | rpoH | DNA-directed RNA polymerase, sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (319 aa) |
| | vapC-4 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (137 aa) |
| | SRAA_0321 | Phage-related protein; Identified by MetaGeneAnnotator; putative. (132 aa) |
| | SRAA_0327 | Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative. (102 aa) |
| | orn | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (196 aa) |
| | SRAA_0365 | Superfamily II DNA and RNA helicase; Identified by MetaGeneAnnotator; putative; Belongs to the DEAD box helicase family. (581 aa) |
| | SRAA_0378 | Cytotoxic translational repressor of toxin-antitoxin stability system; Identified by MetaGeneAnnotator; putative. (110 aa) |
| | SRAA_0384 | Cytotoxic translational repressor of toxin-antitoxin stability system; Identified by MetaGeneAnnotator; putative. (92 aa) |
| | SRAA_0411 | HrpA-like helicase; Identified by MetaGeneAnnotator; putative. (1390 aa) |
| | SRAA_0453 | rRNA methylase; Identified by MetaGeneAnnotator; putative. (274 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (597 aa) |
| | fliA | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (238 aa) |
| | slr0725 | Hypothetical protein; Identified by MetaGeneAnnotator; putative. (163 aa) |
| | SRAA_0509 | Uncharacterized protein conserved in bacteria; Identified by MetaGeneAnnotator; putative. (87 aa) |
| | vapC-5 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (133 aa) |
| | nusA | Transcription elongation factor; Participates in both transcription termination and antitermination. (502 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (123 aa) |
| | truB | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (316 aa) |
| | SRAA_0624 | Uncharacterized protein/domain associated with GTPase; Identified by MetaGeneAnnotator; putative. (373 aa) |
| | priB | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (106 aa) |
| | SRAA_0635 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (350 aa) |
| | SRAA_0637 | 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the pseudouridine synthase RsuA family. (380 aa) |
| | rlmN | Predicted Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (388 aa) |
| | hisS | histidyl-tRNA synthetase; Identified by MetaGeneAnnotator; putative. (431 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (344 aa) |
| | rlmB | rRNA methylase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (253 aa) |
| | SRAA_0690 | Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; Identified by MetaGeneAnnotator; putative. (161 aa) |
| | rlmE | 23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (241 aa) |
| | dusA | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (325 aa) |
| | rimO | 2-methylthioadenine synthetase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (456 aa) |
| | rnr | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (768 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (210 aa) |
| | SRAA_0737 | rRNA methylase; Identified by MetaGeneAnnotator; putative. (256 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (714 aa) |
| | SRAA_0786 | Identified by MetaGeneAnnotator; putative. (497 aa) |
| | rlmH | Uncharacterized conserved protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa) |
| | SRAA_0797 | Identified by MetaGeneAnnotator; putative. (524 aa) |
| | SRAA_0803 | Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Identified by MetaGeneAnnotator; putative. (286 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (635 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha subunit; Identified by MetaGeneAnnotator; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (356 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta subunit; Identified by MetaGeneAnnotator; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (809 aa) |
| | SRAA_0878 | Predicted ATPase or kinase; Identified by MetaGeneAnnotator; putative. (222 aa) |
| | queG | Uncharacterized Fe-S protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (371 aa) |
| | glnS | Glutamyl- and glutaminyl-tRNA synthetase; Identified by MetaGeneAnnotator; putative. (624 aa) |
| | SRAA_0920 | Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative. (112 aa) |
| | vapC-6 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (136 aa) |
| | vapC-7 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (135 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (470 aa) |
| | SRAA_1042 | Cytotoxic translational repressor of toxin-antitoxin stability system; Identified by MetaGeneAnnotator; putative. (117 aa) |
| | dnaG | DNA primase, bacterial type; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (690 aa) |
| | rpoD | DNA-directed RNA polymerase, sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (672 aa) |
| | gcp | Metal-dependent protease with possible chaperone activity; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (352 aa) |
| | SRAA_1120 | N6-adenine-specific methylase; Identified by MetaGeneAnnotator; putative. (211 aa) |
| | trmD | tRNA-(guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (247 aa) |
| | rimM | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (201 aa) |
| | SRAA_1217 | Stress-induced morphogen; Activity unknown; identified by MetaGeneAnnotator; putative; Belongs to the BolA/IbaG family. (96 aa) |
| | tadA | Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (366 aa) |
| | dusB | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (336 aa) |
| | rhlE | Superfamily II DNA and RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (617 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (449 aa) |
| | tilS | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (338 aa) |
| | cysS | cysteinyl-tRNA synthetase; Identified by MetaGeneAnnotator; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (468 aa) |
| | rph | RNase PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (259 aa) |
| | SRAA_1263 | Uncharacterized stress-induced protein; Identified by MetaGeneAnnotator; putative. (299 aa) |
| | rpoZ | DNA-directed RNA polymerase, subunit K/omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa) |
| | rho | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (420 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (728 aa) |
| | SRAA_1378 | DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Identified by MetaGeneAnnotator; putative; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | cas2-2 | Uncharacterized protein predicted to be involved in DNA repair; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (96 aa) |
| | rumA | SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (517 aa) |
| | gltX | Glutamyl- and glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (508 aa) |
| | SRAA_1503 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (323 aa) |
| | rne | Ribonuclease G and E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1059 aa) |
| | vapC-8 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (149 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (1099 aa) |
| | SRAA_1523 | Predicted redox protein, regulator of disulfide bond formation; Identified by MetaGeneAnnotator; putative; Belongs to the sulfur carrier protein TusA family. (75 aa) |
| | gluQ | Glutamyl- and glutaminyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (343 aa) |
| | trmB | Predicted S-adenosylmethionine-dependent methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (262 aa) |
| | SRAA_1554 | Pseudouridylate synthase, 23S RNA-specific; Identified by MetaGeneAnnotator; putative. (315 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (898 aa) |
| | nusB | Transcription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (182 aa) |
| | trmL | Predicted rRNA methylase, SpoU class; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (162 aa) |
| | vapC-9 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (171 aa) |
| | SRAA_1603 | Superfamily II DNA and RNA helicase; Identified by MetaGeneAnnotator; putative; Belongs to the DEAD box helicase family. (493 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (581 aa) |
| | nudH | NTP pyrophosphohydrolase including oxidative damage repair enzymes; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (214 aa) |
| | SRAA_1661 | Predicted endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (147 aa) |
| | truA | Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (261 aa) |
| | rnc | dsRNA-specific ribonuclease; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (236 aa) |
| | SRAA_1717 | DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Identified by MetaGeneAnnotator; putative; Belongs to the sigma-70 factor family. ECF subfamily. (211 aa) |
| | pcnB | tRNA nucleotidyltransferase/poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (573 aa) |
| | SRAA_1740 | Putative translation factor SUA5; Identified by MetaGeneAnnotator; putative; Belongs to the SUA5 family. (211 aa) |
| | SRAA_1742 | tryptophanyl-tRNA synthetase; Identified by MetaGeneAnnotator; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (408 aa) |
| | cca | tRNA nucleotidyltransferase/poly(A) polymerase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (439 aa) |
| | ttcA | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (324 aa) |
| | ybeY | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (162 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (964 aa) |
| | glyS | glycyl-tRNA synthetase, beta subunit; Identified by MetaGeneAnnotator; putative. (748 aa) |
| | glyQ | glycyl-tRNA synthetase, alpha subunit; Identified by MetaGeneAnnotator; putative. (348 aa) |
| | SRAA_1849 | RNA-binding protein with RRM domain; Identified by MetaGeneAnnotator; putative. (146 aa) |
| | miaB | 2-methylthioadenine synthetase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (450 aa) |
| | rsuA | 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the pseudouridine synthase RsuA family. (261 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (425 aa) |
| | rlmJ | Protein involved in catabolism of external DNA; Specifically methylates the adenine in position 2030 of 23S rRNA. (305 aa) |
| | SRAA_1976 | Hypothetical protein; Identified by MetaGeneAnnotator; putative. (819 aa) |
| | SRAA_1986 | Predicted nucleic acid-binding protein, contains PIN domain; Identified by MetaGeneAnnotator; putative. (141 aa) |
| | mraW | Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa) |
| | nusG | Transcription antiterminator; Participates in transcription elongation, termination and antitermination. (196 aa) |
| | SRAA_2039 | 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; Identified by MetaGeneAnnotator; putative. (294 aa) |
| | vapC-10 | Predicted nucleic acid-binding protein, contains PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (135 aa) |
| | SRAA_2083 | Identified by MetaGeneAnnotator; putative. (709 aa) |
| | rnhA | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (154 aa) |
| | SRAA_2090 | ABC-type sugar transport system, periplasmic component; Identified by MetaGeneAnnotator; putative. (322 aa) |
| | argS | arginyl-tRNA synthetase; Identified by MetaGeneAnnotator; putative. (567 aa) |
| | SRAA_2155 | DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (548 aa) |
| | SRAA_2156 | Predicted N6-adenine-specific DNA methylase; Identified by MetaGeneAnnotator; putative; Belongs to the methyltransferase superfamily. (438 aa) |
| | SRAA_2166 | Phenylacetic acid-responsive transcriptional repressor; Identified by MetaGeneAnnotator; putative. (319 aa) |
| | SRAA_2172 | Uncharacterized conserved protein; Identified by MetaGeneAnnotator; putative. (142 aa) |
| | gidB | Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (218 aa) |
| | mnmG | NAD/FAD-utilizing enzyme apparently involved in cell division; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (667 aa) |
| | SRAA_2218 | DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Identified by MetaGeneAnnotator; putative; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa) |
| | SRAA_2222 | Putative translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (370 aa) |
| | higB-2 | Cytotoxic translational repressor of toxin-antitoxin stability system; Identified by MetaGeneAnnotator; putative. (127 aa) |
| | mnmA | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (395 aa) |
| | SRAA_2242 | Inactive homolog of metal-dependent protease, putative molecular chaperone; Identified by MetaGeneAnnotator; putative. (291 aa) |
| | leuS | leucyl-tRNA synthetase; Identified by MetaGeneAnnotator; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (941 aa) |
| | ksgA | Dimethyladenosine transferase (rRNA methylation); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (295 aa) |
| | SRAA_2341 | Uncharacterized protein conserved in bacteria; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (248 aa) |
| | tgt | Queuine/archaeosine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribo [...] (398 aa) |
| | trmE | Predicted GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (484 aa) |
| | SRAA_2374 | RNase P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (121 aa) |
