STRINGSTRING
SRAA_2345 SRAA_2345 SRAA_0088 SRAA_0088 SRAA_0236 SRAA_0236 hemA hemA dxr dxr thrA thrA zwf zwf aroE aroE SRAA_1180 SRAA_1180 SRAA_1185 SRAA_1185 SRAA_1541 SRAA_1541 SRAA_1548 SRAA_1548 SRAA_1556 SRAA_1556 ilvC ilvC SRAA_1698 SRAA_1698 SRAA_1878 SRAA_1878 SRAA_1880 SRAA_1880 proA proA dapB dapB SRAA_2326 SRAA_2326
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRAA_2345NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (477 aa)
SRAA_00883-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; Identified by MetaGeneAnnotator; putative. (300 aa)
SRAA_0236Shikimate 5-dehydrogenase; Identified by MetaGeneAnnotator; putative. (277 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (391 aa)
thrAHomoserine dehydrogenase; Identified by MetaGeneAnnotator; putative. (453 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (487 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa)
SRAA_1180Sulfite reductase; Beta subunit hemoprotein; identified by MetaGeneAnnotator; putative. (609 aa)
SRAA_1185Thioredoxin reductase; Identified by MetaGeneAnnotator; putative. (373 aa)
SRAA_1541Multimeric flavodoxin WrbA; Identified by MetaGeneAnnotator; putative. (184 aa)
SRAA_1548Predicted NAD/FAD-dependent oxidoreductase; Identified by MetaGeneAnnotator; putative. (369 aa)
SRAA_1556Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (179 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
SRAA_1698Aspartate-semialdehyde dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the aspartate-semialdehyde dehydrogenase family. (369 aa)
SRAA_1878Identified by MetaGeneAnnotator; putative. (84 aa)
SRAA_1880Glutathione reductase (NADPH); Identified by MetaGeneAnnotator; putative. (466 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (431 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (270 aa)
SRAA_2326Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
Your Current Organism:
Serpentinomonas raichei
NCBI taxonomy Id: 1458425
Other names: Comamonadaceae bacterium A1, Comamonadaceae bacterium H1, S. raichei, strain A1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.