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ppsA ppsA eno eno tpiA tpiA gpmA gpmA pgi pgi glk glk SRAA_0982 SRAA_0982 SRAA_1085 SRAA_1085 pdhC pdhC aceE aceE SRAA_1154 SRAA_1154 fbp1 fbp1 acs acs SRAA_1677 SRAA_1677 SRAA_1755 SRAA_1755 pckA pckA SRAA_2209 SRAA_2209 pfkA pfkA pyk pyk fbp1-2 fbp1-2 SRAA_2326 SRAA_2326 pgk pgk fbaA-2 fbaA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppsAPhosphoenolpyruvate synthase/pyruvate phosphate dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (797 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
gpmAPhosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa)
pgiGlucose-6-phosphate isomerase; Identified by MetaGeneAnnotator; putative; Belongs to the GPI family. (544 aa)
glkGlucokinase; Identified by MetaGeneAnnotator; putative; Belongs to the bacterial glucokinase family. (333 aa)
SRAA_0982Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (479 aa)
SRAA_1085Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (611 aa)
pdhCAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (442 aa)
aceEPyruvate dehydrogenase complex, dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (905 aa)
SRAA_1154Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Identified by MetaGeneAnnotator; putative. (619 aa)
fbp1Fructose-1,6-bisphosphatase; Identified by MetaGeneAnnotator; putative; Belongs to the FBPase class 1 family. (353 aa)
acsAcyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa)
SRAA_1677NAD-dependent aldehyde dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the aldehyde dehydrogenase family. (506 aa)
SRAA_1755Fructose-2,6-bisphosphatase; Identified by MetaGeneAnnotator; putative. (212 aa)
pckAPhosphoenolpyruvate carboxykinase GTP; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (629 aa)
SRAA_2209Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Identified by MetaGeneAnnotator; putative. (545 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (371 aa)
pykPyruvate kinase; Identified by MetaGeneAnnotator; putative; Belongs to the pyruvate kinase family. (476 aa)
fbp1-2Fructose-1,6-bisphosphatase; Identified by MetaGeneAnnotator; putative; Belongs to the FBPase class 1 family. (364 aa)
SRAA_2326Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
pgk3-phosphoglycerate kinase; Identified by MetaGeneAnnotator; putative; Belongs to the phosphoglycerate kinase family. (446 aa)
fbaA-2Fructose/tagatose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (355 aa)
Your Current Organism:
Serpentinomonas raichei
NCBI taxonomy Id: 1458425
Other names: Comamonadaceae bacterium A1, Comamonadaceae bacterium H1, S. raichei, strain A1
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