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thrB thrB SRAA_0399 SRAA_0399 SRAA_0525 SRAA_0525 trpB-2 trpB-2 SRAA_0538 SRAA_0538 SRAA_0670 SRAA_0670 thrA thrA thrC thrC gpmA gpmA SRAA_0982 SRAA_0982 SRAA_0988 SRAA_0988 SRAA_1085 SRAA_1085 lysC lysC SRAA_1418 SRAA_1418 gcvH gcvH gcvP gcvP serC serC glyA glyA SRAA_1698 SRAA_1698 trpB trpB trpA trpA SRAA_1755 SRAA_1755 ilvA ilvA SRAA_1952 SRAA_1952
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thrBPutative homoserine kinase type II; Identified by MetaGeneAnnotator; putative; protein kinase fold; Belongs to the pseudomonas-type ThrB family. (318 aa)
SRAA_0399Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenase, large terminal subunit; Identified by MetaGeneAnnotator; putative. (386 aa)
SRAA_0525Phosphatidylserine synthase; Identified by MetaGeneAnnotator; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (298 aa)
trpB-2Predicted alternative tryptophan synthase beta-subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (457 aa)
SRAA_0538Phosphoserine phosphatase; Identified by MetaGeneAnnotator; putative. (242 aa)
SRAA_0670Phosphoglycerate dehydrogenase and related dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
thrAHomoserine dehydrogenase; Identified by MetaGeneAnnotator; putative. (453 aa)
thrCThreonine synthase; Identified by MetaGeneAnnotator; putative. (476 aa)
gpmAPhosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa)
SRAA_0982Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (479 aa)
SRAA_0988Lactate dehydrogenase and related dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
SRAA_1085Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (611 aa)
lysCAspartokinase; Identified by MetaGeneAnnotator; putative; Belongs to the aspartokinase family. (427 aa)
SRAA_1418Glycine cleavage system T protein; Aminomethyltransferase; identified by MetaGeneAnnotator; putative. (394 aa)
gcvHGlycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa)
gcvPGlycine cleavage system protein P (pyridoxal-binding), C-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (992 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (382 aa)
glyAGlycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa)
SRAA_1698Aspartate-semialdehyde dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the aspartate-semialdehyde dehydrogenase family. (369 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (280 aa)
SRAA_1755Fructose-2,6-bisphosphatase; Identified by MetaGeneAnnotator; putative. (212 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (525 aa)
SRAA_1952Putative glycerate kinase; Identified by MetaGeneAnnotator; putative. (441 aa)
Your Current Organism:
Serpentinomonas raichei
NCBI taxonomy Id: 1458425
Other names: Comamonadaceae bacterium A1, Comamonadaceae bacterium H1, S. raichei, strain A1
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