Your Input: | |
| | ubiA | 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (295 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (314 aa) |
| | SRAA_0029 | Glycerol-3-phosphate dehydrogenase; Identified by MetaGeneAnnotator; putative. (520 aa) |
| | SRAA_0047 | 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; Identified by MetaGeneAnnotator; putative; Belongs to the UbiD family. (494 aa) |
| | ubiX | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (198 aa) |
| | aroG | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (375 aa) |
| | SRAA_0097 | FAD/FMN-containing dehydrogenase; Identified by MetaGeneAnnotator; putative. (507 aa) |
| | argJ | N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (301 aa) |
| | hemE | uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (372 aa) |
| | SRAA_0221 | Isopropylmalate/homocitrate/citramalate synthase; Identified by MetaGeneAnnotator; putative. (305 aa) |
| | SRAA_0236 | Shikimate 5-dehydrogenase; Identified by MetaGeneAnnotator; putative. (277 aa) |
| | SRAA_0256 | dTDP-D-glucose 4,6-dehydratase; Identified by MetaGeneAnnotator; putative; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (356 aa) |
| | SRAA_0257 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (311 aa) |
| | SRAA_0258 | dTDP-glucose pyrophosphorylase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (290 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (189 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (393 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (431 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (181 aa) |
| | aroB | 3-dehydroquinate synthetase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (345 aa) |
| | SRAA_0278 | Glutamate synthase domain 2; Identified by MetaGeneAnnotator; putative. (1581 aa) |
| | gltD | NADPH-dependent glutamate synthase beta chain and related oxidoreductase; Identified by MetaGeneAnnotator; putative. (491 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (239 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (455 aa) |
| | hisC | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Identified by MetaGeneAnnotator; putative; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Identified by MetaGeneAnnotator; putative. (195 aa) |
| | hisH | Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (231 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide ProFAR isomerase; Identified by MetaGeneAnnotator; putative. (246 aa) |
| | hisF | Imidazoleglycerol-phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (268 aa) |
| | ilvE | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (325 aa) |
| | SRAA_0360 | Zn-dependent protease with chaperone function; Identified by MetaGeneAnnotator; putative. (423 aa) |
| | thrB | Putative homoserine kinase type II; Identified by MetaGeneAnnotator; putative; protein kinase fold; Belongs to the pseudomonas-type ThrB family. (318 aa) |
| | SRAA_0375 | Nucleoside-diphosphate-sugar pyrophosphorylase; Identified by MetaGeneAnnotator; putative; involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (367 aa) |
| | SRAA_0401 | Geranylgeranyl pyrophosphate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the FPP/GGPP synthase family. (317 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa) |
| | argA | Acetylglutamate kinase; Identified by MetaGeneAnnotator; putative; Belongs to the acetyltransferase family. ArgA subfamily. (449 aa) |
| | SRAA_0432 | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Identified by MetaGeneAnnotator; putative. (334 aa) |
| | ppsA | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (797 aa) |
| | SRAA_0452 | Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; Identified by MetaGeneAnnotator; putative; Belongs to the inositol monophosphatase superfamily. (281 aa) |
| | cysE | Serine acetyltransferase; Identified by MetaGeneAnnotator; putative. (255 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa) |
| | ubiE | Methylase involved in ubiquinone/menaquinone biosynthesis; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (243 aa) |
| | SRAA_0525 | Phosphatidylserine synthase; Identified by MetaGeneAnnotator; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (298 aa) |
| | leuA | Isopropylmalate/homocitrate/citramalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (516 aa) |
| | SRAA_0534 | Transcriptional regulators; Containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; identified by MetaGeneAnnotator; putative. (407 aa) |
| | trpB-2 | Predicted alternative tryptophan synthase beta-subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (457 aa) |
| | SRAA_0538 | Phosphoserine phosphatase; Identified by MetaGeneAnnotator; putative. (242 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (440 aa) |
| | SRAA_0567 | Phosphomannomutase; Identified by MetaGeneAnnotator; putative. (467 aa) |
| | SRAA_0575 | Predicted thioesterase; Identified by MetaGeneAnnotator; putative. (139 aa) |
| | SRAA_0576 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa) |
| | atoB | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | SRAA_0596 | Phytoene/squalene synthetase; Identified by MetaGeneAnnotator; putative. (288 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa) |
| | ispG | Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (420 aa) |
| | SRAA_0657 | Enoyl-[acyl-carrier-protein] reductase (NADH); Identified by MetaGeneAnnotator; putative. (269 aa) |
| | SRAA_0665 | acyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative. (420 aa) |
| | SRAA_0670 | Phosphoglycerate dehydrogenase and related dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (344 aa) |
| | hisZ | ATP phosphoribosyltransferase involved in histidine biosynthesis; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (405 aa) |
| | SRAA_0682 | Cystathionine beta-lyase/cystathionine gamma-synthase; Identified by MetaGeneAnnotator; putative. (415 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (223 aa) |
| | SRAA_0700 | Glycerol-3-phosphate dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (529 aa) |
| | SRAA_0705 | Dehydrogenase with different specificities related to short-chain alcohol dehydrogenase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | uppS | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (251 aa) |
| | SRAA_0719 | CDP-diglyceride synthetase; Identified by MetaGeneAnnotator; putative; Belongs to the CDS family. (275 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (391 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa) |
| | SRAA_0764 | Aspartate/tyrosine/aromatic aminotransferase; Identified by MetaGeneAnnotator; putative. (412 aa) |
| | thrA | Homoserine dehydrogenase; Identified by MetaGeneAnnotator; putative. (453 aa) |
| | thrC | Threonine synthase; Identified by MetaGeneAnnotator; putative. (476 aa) |
| | icd | Isocitrate dehydrogenase; Identified by MetaGeneAnnotator; putative. (417 aa) |
| | purD | Phosphoribosylamine-glycine ligase; Identified by MetaGeneAnnotator; putative; Belongs to the GARS family. (430 aa) |
| | hemF | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (306 aa) |
| | SRAA_0814 | Dehydrogenase with different specificities related to short-chain alcohol dehydrogenase; Identified by MetaGeneAnnotator; putative. (245 aa) |
| | SRAA_0823 | Acetolactate synthase I/II/III large subunit; Identified by MetaGeneAnnotator; putative; Belongs to the TPP enzyme family. (601 aa) |
| | gpmA | Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa) |
| | panC | Panthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (299 aa) |
| | panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (291 aa) |
| | ilvD | Dihydroxyacid dehydratase/phosphogluconate dehydratase; Identified by MetaGeneAnnotator; putative; Belongs to the IlvD/Edd family. (641 aa) |
| | SRAA_0860 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; Identified by MetaGeneAnnotator; putative; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (460 aa) |
| | SRAA_0862 | Isocitrate lyase; Identified by MetaGeneAnnotator; putative. (443 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) |
| | aroQ | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | guaB | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (489 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by MetaGeneAnnotator; putative; Belongs to the GPI family. (544 aa) |
| | pgl | 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (272 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (487 aa) |
| | glk | Glucokinase; Identified by MetaGeneAnnotator; putative; Belongs to the bacterial glucokinase family. (333 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa) |
| | SRAA_0951 | Uncharacterized protein, possibly involved in aromatic compounds catabolism; Identified by MetaGeneAnnotator; putative. (136 aa) |
| | SRAA_0952 | L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; Identified by MetaGeneAnnotator; putative. (357 aa) |
| | adk | Adenylate kinase and related kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | SRAA_0974 | acetyl-CoA carboxylase, carboxyltransferase component, subunits alpha and beta; Identified by MetaGeneAnnotator; putative. (510 aa) |
| | SRAA_0977 | acetyl/propionyl-CoA carboxylase, alpha subunit; Identified by MetaGeneAnnotator; putative. (697 aa) |
| | sucA | 2-oxoglutarate dehydrogenase complex, dehydrogenase E1 component, and related enzymes; Identified by MetaGeneAnnotator; putative. (959 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa) |
| | SRAA_0982 | Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (479 aa) |
| | SRAA_0988 | Lactate dehydrogenase and related dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa) |
| | purL | Phosphoribosylformylglycinamidine FGAM synthase, synthetase domain; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1398 aa) |
| | hemH | Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (363 aa) |
| | metE | Methionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (783 aa) |
| | SRAA_1085 | Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (611 aa) |
| | pdhC | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (442 aa) |
| | aceE | Pyruvate dehydrogenase complex, dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (905 aa) |
| | SRAA_1101 | uroporphyrinogen-III methylase; Identified by MetaGeneAnnotator; putative; Belongs to the precorrin methyltransferase family. (274 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa) |
| | prs | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (327 aa) |
| | SRAA_1154 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Identified by MetaGeneAnnotator; putative. (619 aa) |
| | fbp1 | Fructose-1,6-bisphosphatase; Identified by MetaGeneAnnotator; putative; Belongs to the FBPase class 1 family. (353 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa) |
| | acs | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa) |
| | SRAA_1170 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (516 aa) |
| | cysD-1 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase/FAD synthetase and related enzymes; Identified by MetaGeneAnnotator; putative. (561 aa) |
| | SRAA_1183 | GTPase, sulfate adenylate transferase subunit 1; Identified by MetaGeneAnnotator; putative. (441 aa) |
| | SRAA_1207 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | purH | AICAR transformylase/IMP cyclohydrolase PurH; Identified by MetaGeneAnnotator; putative; only IMP cyclohydrolase domain in Aful. (534 aa) |
| | ispH | Penicillin tolerance protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (312 aa) |
| | lysC | Aspartokinase; Identified by MetaGeneAnnotator; putative; Belongs to the aspartokinase family. (427 aa) |
| | accA | acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (336 aa) |
| | SRAA_1281 | Phospholipid N-methyltransferase; Identified by MetaGeneAnnotator; putative. (221 aa) |
| | dapA | Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | aspC | Aspartate/tyrosine/aromatic aminotransferase; Identified by MetaGeneAnnotator; putative. (398 aa) |
| | surE | Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (289 aa) |
| | SRAA_1418 | Glycine cleavage system T protein; Aminomethyltransferase; identified by MetaGeneAnnotator; putative. (394 aa) |
| | gcvH | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa) |
| | gcvP | Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (992 aa) |
| | SRAA_1421 | Acetolactate synthase I/II/III large subunit; Identified by MetaGeneAnnotator; putative. (550 aa) |
| | cmk | 5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. (688 aa) |
| | SRAA_1428 | Prephenate dehydrogenase; Identified by MetaGeneAnnotator; putative. (329 aa) |
| | SRAA_1429 | Prephenate dehydratase; Identified by MetaGeneAnnotator; putative. (362 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (382 aa) |
| | ubiG | 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (237 aa) |
| | gltX | Glutamyl- and glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (508 aa) |
| | purF | Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (501 aa) |
| | yaiE | Uncharacterized protein conserved in bacteria; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (106 aa) |
| | SRAA_1486 | Argininosuccinate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (442 aa) |
| | gcdH1 | acyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative. (395 aa) |
| | SRAA_1488 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | plsY | Predicted membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (209 aa) |
| | SRAA_1501 | Predicted phosphatase; Identified by MetaGeneAnnotator; putative. (219 aa) |
| | SRAA_1512 | Phospholipid N-methyltransferase; Identified by MetaGeneAnnotator; putative. (176 aa) |
| | SRAA_1541 | Multimeric flavodoxin WrbA; Identified by MetaGeneAnnotator; putative. (184 aa) |
| | SRAA_1553 | Pyrimidine reductase, riboflavin biosynthesis; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (386 aa) |
| | ribH | Riboflavin synthase beta-chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (167 aa) |
| | ribA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (377 aa) |
| | ribE | Riboflavin synthase alpha chain; Identified by MetaGeneAnnotator; putative. (206 aa) |
| | glyA | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | ilvH | Acetolactate synthase, small regulatory subunit; Identified by MetaGeneAnnotator; putative. (163 aa) |
| | ilvB | Acetolactate synthase; Identified by MetaGeneAnnotator; putative. (592 aa) |
| | SRAA_1583 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (136 aa) |
| | argD | Ornithine/acetylornithine aminotransferase; Identified by MetaGeneAnnotator; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (403 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (320 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (392 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphohydrolase; Identified by MetaGeneAnnotator; putative. (176 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (143 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | bccP | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | SRAA_1657 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by MetaGeneAnnotator; putative. (275 aa) |
| | hemL | Glutamate-1-semialdehyde aminotransferase; Identified by MetaGeneAnnotator; putative. (435 aa) |
| | SRAA_1677 | NAD-dependent aldehyde dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | acnB | Identified by MetaGeneAnnotator; putative; Belongs to the aconitase/IPM isomerase family. (863 aa) |
| | mdh | Malate/lactate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa) |
| | SRAA_1686 | Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; Identified by MetaGeneAnnotator; putative. (144 aa) |
| | SRAA_1687 | Succinate dehydrogenase, hydrophobic anchor subunit; Identified by MetaGeneAnnotator; putative. (121 aa) |
| | sdhA | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Identified by MetaGeneAnnotator; putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (603 aa) |
| | sdhB | Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Identified by MetaGeneAnnotator; putative. (234 aa) |
| | gltA | Citrate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the citrate synthase family. (436 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa) |
| | leuB | Isocitrate/isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (356 aa) |
| | SRAA_1698 | Aspartate-semialdehyde dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the aspartate-semialdehyde dehydrogenase family. (369 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Identified by MetaGeneAnnotator; putative; Belongs to the TrpF family. (223 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (280 aa) |
| | accD | acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa) |
| | fabG | Dehydrogenase with different specificities related to short-chain alcohol dehydrogenase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa) |
| | SRAA_1722 | S-malonyltransferase; Identified by MetaGeneAnnotator; putative. (316 aa) |
| | plsX | Fatty acid/phospholipid biosynthesis enzyme; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (342 aa) |
| | purM | Phosphoribosylaminoimidazole AIR synthetase; Identified by MetaGeneAnnotator; putative. (350 aa) |
| | SRAA_1755 | Fructose-2,6-bisphosphatase; Identified by MetaGeneAnnotator; putative. (212 aa) |
| | SRAA_1770 | Hypothetical protein; Identified by MetaGeneAnnotator; putative. (309 aa) |
| | purN | Folate-dependent phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (193 aa) |
| | katG | Catalase, peroxidase I; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (731 aa) |
| | SRAA_1779 | FAD synthase; Identified by MetaGeneAnnotator; putative; Belongs to the ribF family. (352 aa) |
| | SRAA_1787 | Dehydrogenase with different specificities related to short-chain alcohol dehydrogenase; Identified by MetaGeneAnnotator; putative. (264 aa) |
| | SRAA_1791 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | coq7 | Ubiquinone biosynthesis protein COQ7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (220 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (525 aa) |
| | SRAA_1817 | acyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative. (378 aa) |
| | SRAA_1818 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | SRAA_1825 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by MetaGeneAnnotator; putative. (251 aa) |
| | argC | Acetylglutamate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (306 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa) |
| | metX | Homoserine acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (423 aa) |
| | SRAA_1860 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterase; Identified by MetaGeneAnnotator; putative; Belongs to the 5'-nucleotidase family. (509 aa) |
| | SRAA_1873 | Isocitrate/isopropylmalate dehydrogenase; Identified by MetaGeneAnnotator; putative. (490 aa) |
| | SRAA_1876 | Trehalose-6-phosphate synthase; Identified by MetaGeneAnnotator; putative. (787 aa) |
| | otsB | Trehalose-6-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (276 aa) |
| | SRAA_1882 | 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; Identified by MetaGeneAnnotator; putative. (378 aa) |
| | paaG-2 | enoyl-CoA hydratase/carnithine racemase; Identified by MetaGeneAnnotator; putative; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | fadA | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (300 aa) |
| | SRAA_1922 | Uncharacterized enzyme of heme biosynthesis; Identified by MetaGeneAnnotator; putative. (471 aa) |
| | SRAA_1923 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (270 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (333 aa) |
| | argH | Argininosuccinate lyase; Identified by MetaGeneAnnotator; putative. (494 aa) |
| | SRAA_1952 | Putative glycerate kinase; Identified by MetaGeneAnnotator; putative. (441 aa) |
| | SRAA_1961 | Methionine synthase I, cobalamin-binding domain; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (900 aa) |
| | SRAA_1971 | Geranylgeranyl pyrophosphate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the FPP/GGPP synthase family. (338 aa) |
| | purB | Adenylosuccinate lyase; Identified by MetaGeneAnnotator; putative; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (498 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (291 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the TrpC family. (265 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (349 aa) |
| | SRAA_2033 | Anthranilate/para-aminobenzoate synthase component II; Identified by MetaGeneAnnotator; putative. (195 aa) |
| | SRAA_2034 | Chorismate mutase; Identified by MetaGeneAnnotator; putative. (121 aa) |
| | trpE | Anthranilate/para-aminobenzoate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismat [...] (500 aa) |
| | SRAA_2064 | Pentose-5-phosphate-3-epimerase; Identified by MetaGeneAnnotator; putative; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa) |
| | SRAA_2127 | Predicted membrane protein; Identified by MetaGeneAnnotator; putative. (157 aa) |
| | SRAA_2129 | FAD/FMN-containing dehydrogenase; Identified by MetaGeneAnnotator; putative. (373 aa) |
| | glcF | Fe-S oxidoreductase; Identified by MetaGeneAnnotator; putative. (432 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase GTP; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (629 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Identified by MetaGeneAnnotator; putative; Belongs to the ALAD family. (335 aa) |
| | glcB | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (741 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase (NADH); Identified by MetaGeneAnnotator; putative. (275 aa) |
| | SRAA_2209 | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Identified by MetaGeneAnnotator; putative. (545 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (412 aa) |
| | purE | Phosphoribosylcarboxyaminoimidazole NCAIR mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide SAICAR synthase; Identified by MetaGeneAnnotator; putative; Belongs to the SAICAR synthetase family. (308 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (431 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (371 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (270 aa) |
| | SRAA_2316 | Ribulose bisphosphate carboxylase small subunit; Identified by MetaGeneAnnotator; putative. (108 aa) |
| | cbbL | Ribulose 1,5-bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (473 aa) |
| | pyk | Pyruvate kinase; Identified by MetaGeneAnnotator; putative; Belongs to the pyruvate kinase family. (476 aa) |
| | fbp1-2 | Fructose-1,6-bisphosphatase; Identified by MetaGeneAnnotator; putative; Belongs to the FBPase class 1 family. (364 aa) |
| | SRAA_2324 | Transketolase; Identified by MetaGeneAnnotator; putative; Belongs to the transketolase family. (676 aa) |
| | SRAA_2325 | Predicted phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (232 aa) |
| | SRAA_2326 | Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | pgk | 3-phosphoglycerate kinase; Identified by MetaGeneAnnotator; putative; Belongs to the phosphoglycerate kinase family. (446 aa) |
| | fbaA-2 | Fructose/tagatose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (355 aa) |
| | SRAA_2360 | Methionine synthase I (cobalamin-dependent), methyltransferase domain; Identified by MetaGeneAnnotator; putative. (350 aa) |
| | aroF | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (366 aa) |
