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| | SRAA_0065 | Hypothetical protein; Identified by MetaGeneAnnotator; putative. (100 aa) |
| | SRAA_0066 | Uncharacterized anaerobic dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (711 aa) |
| | SRAA_0068 | NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; Identified by MetaGeneAnnotator; putative. (523 aa) |
| | SRAA_0069 | NADH:ubiquinone oxidoreductase 24 kD subunit; Identified by MetaGeneAnnotator; putative. (172 aa) |
| | SRAA_0079 | 3-hydroxyacyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative. (283 aa) |
| | ppsA | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (797 aa) |
| | cysE | Serine acetyltransferase; Identified by MetaGeneAnnotator; putative. (255 aa) |
| | SRAA_0538 | Phosphoserine phosphatase; Identified by MetaGeneAnnotator; putative. (242 aa) |
| | SRAA_0576 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa) |
| | atoB | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | phbB | Dehydrogenase with different specificities related to short-chain alcohol dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | SRAA_0670 | Phosphoglycerate dehydrogenase and related dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (223 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa) |
| | SRAA_0760 | Glutamate dehydrogenase/leucine dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (441 aa) |
| | icd | Isocitrate dehydrogenase; Identified by MetaGeneAnnotator; putative. (417 aa) |
| | gpmA | Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa) |
| | SRAA_0862 | Isocitrate lyase; Identified by MetaGeneAnnotator; putative. (443 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (918 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by MetaGeneAnnotator; putative; Belongs to the GPI family. (544 aa) |
| | SRAA_0930 | 2-keto-3-deoxy-6-phosphogluconate aldolase; Identified by MetaGeneAnnotator; putative. (237 aa) |
| | edd | Dihydroxyacid dehydratase/phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (612 aa) |
| | pgl | 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (272 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (487 aa) |
| | glk | Glucokinase; Identified by MetaGeneAnnotator; putative; Belongs to the bacterial glucokinase family. (333 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa) |
| | SRAA_0970 | methylmalonyl-CoA mutase, N-terminal domain/subunit; Identified by MetaGeneAnnotator; putative. (715 aa) |
| | SRAA_0974 | acetyl-CoA carboxylase, carboxyltransferase component, subunits alpha and beta; Identified by MetaGeneAnnotator; putative. (510 aa) |
| | SRAA_0977 | acetyl/propionyl-CoA carboxylase, alpha subunit; Identified by MetaGeneAnnotator; putative. (697 aa) |
| | sucA | 2-oxoglutarate dehydrogenase complex, dehydrogenase E1 component, and related enzymes; Identified by MetaGeneAnnotator; putative. (959 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa) |
| | SRAA_0982 | Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (479 aa) |
| | SRAA_1085 | Dihydrolipoyl dehydrogenase; Identified by MetaGeneAnnotator; putative. (611 aa) |
| | pdhC | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (442 aa) |
| | aceE | Pyruvate dehydrogenase complex, dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (905 aa) |
| | folD | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | prs | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (327 aa) |
| | SRAA_1154 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Identified by MetaGeneAnnotator; putative. (619 aa) |
| | fbp1 | Fructose-1,6-bisphosphatase; Identified by MetaGeneAnnotator; putative; Belongs to the FBPase class 1 family. (353 aa) |
| | acs | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa) |
| | SRAA_1170 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (516 aa) |
| | SRAA_1207 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | SRAA_1208 | 3-hydroxyacyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the enoyl-CoA hydratase/isomerase family. (704 aa) |
| | iolA | NAD-dependent aldehyde dehydrogenase; Identified by MetaGeneAnnotator; putative. (500 aa) |
| | accA | acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (336 aa) |
| | SRAA_1365 | enoyl-CoA hydratase/carnithine racemase; Identified by MetaGeneAnnotator; putative. (267 aa) |
| | SRAA_1418 | Glycine cleavage system T protein; Aminomethyltransferase; identified by MetaGeneAnnotator; putative. (394 aa) |
| | gcvH | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa) |
| | gcvP | Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (992 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (382 aa) |
| | SRAA_1489 | 3-hydroxyacyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative. (683 aa) |
| | glyA | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa) |
| | SRAA_1594 | Alcohol dehydrogenase, class IV; Identified by MetaGeneAnnotator; putative. (383 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | bccP | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | acnB | Identified by MetaGeneAnnotator; putative; Belongs to the aconitase/IPM isomerase family. (863 aa) |
| | mdh | Malate/lactate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa) |
| | SRAA_1686 | Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; Identified by MetaGeneAnnotator; putative. (144 aa) |
| | SRAA_1687 | Succinate dehydrogenase, hydrophobic anchor subunit; Identified by MetaGeneAnnotator; putative. (121 aa) |
| | sdhA | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Identified by MetaGeneAnnotator; putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (603 aa) |
| | sdhB | Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Identified by MetaGeneAnnotator; putative. (234 aa) |
| | gltA | Citrate synthase; Identified by MetaGeneAnnotator; putative; Belongs to the citrate synthase family. (436 aa) |
| | accD | acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa) |
| | SRAA_1755 | Fructose-2,6-bisphosphatase; Identified by MetaGeneAnnotator; putative. (212 aa) |
| | SRAA_1791 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (525 aa) |
| | SRAA_1817 | acyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative. (378 aa) |
| | SRAA_1818 | acetyl-CoA acetyltransferase; Identified by MetaGeneAnnotator; putative; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa) |
| | SRAA_1873 | Isocitrate/isopropylmalate dehydrogenase; Identified by MetaGeneAnnotator; putative. (490 aa) |
| | SRAA_1901 | 3-hydroxyacyl-CoA dehydrogenase; Identified by MetaGeneAnnotator; putative. (810 aa) |
| | SRAA_1952 | Putative glycerate kinase; Identified by MetaGeneAnnotator; putative. (441 aa) |
| | SRAA_1969 | 5,10-methylenetetrahydrofolate reductase; Identified by MetaGeneAnnotator; putative; Belongs to the methylenetetrahydrofolate reductase family. (281 aa) |
| | SRAA_2064 | Pentose-5-phosphate-3-epimerase; Identified by MetaGeneAnnotator; putative; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa) |
| | glcB | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (741 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa) |
| | SRAA_2209 | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Identified by MetaGeneAnnotator; putative. (545 aa) |
| | SRAA_2210 | Phosphotransacetylase; Identified by MetaGeneAnnotator; putative. (496 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (371 aa) |
| | SRAA_2316 | Ribulose bisphosphate carboxylase small subunit; Identified by MetaGeneAnnotator; putative. (108 aa) |
| | cbbL | Ribulose 1,5-bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (473 aa) |
| | pyk | Pyruvate kinase; Identified by MetaGeneAnnotator; putative; Belongs to the pyruvate kinase family. (476 aa) |
| | fbp1-2 | Fructose-1,6-bisphosphatase; Identified by MetaGeneAnnotator; putative; Belongs to the FBPase class 1 family. (364 aa) |
| | cbbP2 | Phosphoribulokinase; Identified by MetaGeneAnnotator; putative. (294 aa) |
| | SRAA_2324 | Transketolase; Identified by MetaGeneAnnotator; putative; Belongs to the transketolase family. (676 aa) |
| | SRAA_2326 | Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Identified by MetaGeneAnnotator; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | pgk | 3-phosphoglycerate kinase; Identified by MetaGeneAnnotator; putative; Belongs to the phosphoglycerate kinase family. (446 aa) |
| | fbaA-2 | Fructose/tagatose bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (355 aa) |
| | maeB | Malic enzyme; Identified by MetaGeneAnnotator; putative. (798 aa) |
| | SRAA_2354 | Phosphotransacetylase; Identified by MetaGeneAnnotator; putative. (477 aa) |
