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CDO59419.1 CDO59419.1 CDO59467.1 CDO59467.1 CDO59469.1 CDO59469.1 CDO59470.1 CDO59470.1 sucD sucD sucC sucC mdh mdh CDO59488.1 CDO59488.1 CDO59490.1 CDO59490.1 CDO59491.1 CDO59491.1 CDO59492.1 CDO59492.1 CDO59542.1 CDO59542.1 folD folD CDO59711.1 CDO59711.1 CDO59740.1 CDO59740.1 CDO59827.1 CDO59827.1 pckA pckA CDO60078.1 CDO60078.1 CDO60366.1 CDO60366.1 CDO60445.1 CDO60445.1 gcvH gcvH gcvPA gcvPA CDO60448.1 CDO60448.1 glcB glcB CDO60607.1 CDO60607.1 CDO60709.1 CDO60709.1 CDO60757.1 CDO60757.1 CDO60942.1 CDO60942.1 CDO58488.1 CDO58488.1 CDO58489.1 CDO58489.1 CDO60986.1 CDO60986.1 CDO61010.1 CDO61010.1 pdhA pdhA CDO61055.1 CDO61055.1 CDO61056.1 CDO61056.1 CDO61058.1 CDO61058.1 CDO61101.1 CDO61101.1 CDO61178.1 CDO61178.1 glyA glyA CDO58617.1 CDO58617.1 fumC fumC CDO58694.1 CDO58694.1 CDO58799.1 CDO58799.1 CDO59030.1 CDO59030.1 CDO59104.1 CDO59104.1 CDO59105.1 CDO59105.1 CDO59106.1 CDO59106.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDO59419.1Acetyl-CoA hydrolase. (616 aa)
CDO59467.1Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (468 aa)
CDO59469.1Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (412 aa)
CDO59470.12-oxoglutarate dehydrogenase E1 component. (988 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (359 aa)
CDO59488.1Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa)
CDO59490.1Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (606 aa)
CDO59491.1Succinate dehydrogenase hydrophobic membrane anchor protein. (127 aa)
CDO59492.1Succinate dehydrogenase cytochrome b-556 subunit. (138 aa)
CDO59542.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (926 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa)
CDO59711.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (218 aa)
CDO59740.1N-succinyl-L,L-diaminopimelate aminotransferase alternative. (417 aa)
CDO59827.1NADP-dependent malic enzyme. (757 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa)
CDO60078.1Gamma-glutamyltranspeptidase. (508 aa)
CDO60366.1Isocitrate lyase. (294 aa)
CDO60445.1Aminomethyltransferase (glycine cleavage system T protein). (377 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
gcvPAGlycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (453 aa)
CDO60448.1Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein). (505 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (709 aa)
CDO60607.1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa)
CDO60709.1Aminomethyltransferase (glycine cleavage system T protein); Belongs to the GcvT family. (391 aa)
CDO60757.1Glutathione reductase; Maintains high levels of reduced glutathione. (460 aa)
CDO60942.1Aldehyde dehydrogenase; Probable coniferyl aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
CDO58488.1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)
CDO58489.1Ion transport protein. (411 aa)
CDO60986.1Hypothetical protein. (578 aa)
CDO61010.1Citrate synthase (si); Belongs to the citrate synthase family. (432 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (369 aa)
CDO61055.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (470 aa)
CDO61056.1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (456 aa)
CDO61058.1Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (464 aa)
CDO61101.1Immune-responsive protein 1. (445 aa)
CDO61178.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (469 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (432 aa)
CDO58617.12,4-dienoyl-CoA reductase [NADPH]. (685 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
CDO58694.15-oxoprolinase. (1209 aa)
CDO58799.1Isocitrate lyase. (427 aa)
CDO59030.1Glutamate synthase [NADPH] large chain. (1559 aa)
CDO59104.12-methylcitrate dehydratase. (501 aa)
CDO59105.1Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (297 aa)
CDO59106.12-methylcitrate synthase; Belongs to the citrate synthase family. (381 aa)
Your Current Organism:
Phaeomarinobacter ectocarpi
NCBI taxonomy Id: 1458461
Other names: C. Phaeomarinobacter ectocarpi, Candidatus Phaeomarinobacter ectocarpi, bacterium Ec32
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