STRINGSTRING
bioA bioA KON87930.1 KON87930.1 KON88175.1 KON88175.1 KON88206.1 KON88206.1 KON86939.1 KON86939.1 KON85474.1 KON85474.1 KON85486.1 KON85486.1 KON85713.1 KON85713.1 glyA glyA KON86265.1 KON86265.1 KON86445.1 KON86445.1 KON86452.1 KON86452.1 KON86518.1 KON86518.1 KON86522.1 KON86522.1 KON90088.1 KON90088.1 KON89995.1 KON89995.1 kynU kynU KON89847.1 KON89847.1 KON89836.1 KON89836.1 KON89759.1 KON89759.1 KON89758.1 KON89758.1 hemL-2 hemL-2 KON89671.1 KON89671.1 serC serC argD argD KON89324.1 KON89324.1 KON89295.1 KON89295.1 KON89255.1 KON89255.1 KON88814.1 KON88814.1 hisC-2 hisC-2 KON88625.1 KON88625.1 KON88426.1 KON88426.1 KON88425.1 KON88425.1 KON88412.1 KON88412.1 rocD rocD KON86730.1 KON86730.1 KON86735.1 KON86735.1 hemL hemL KON86904.1 KON86904.1 gcvPA gcvPA gcvPB gcvPB hisC hisC KON90267.1 KON90267.1 KON87503.1 KON87503.1 KON87534.1 KON87534.1 KON87538.1 KON87538.1 KON87735.1 KON87735.1 KON87805.1 KON87805.1 KON87830.1 KON87830.1 KON87831.1 KON87831.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (453 aa)
KON87930.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (435 aa)
KON88175.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
KON88206.1Septum site-determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
KON86939.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
KON85474.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
KON85486.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
KON85713.1Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
KON86265.1Pleiotropic regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (370 aa)
KON86445.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
KON86452.1Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (409 aa)
KON86518.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KON86522.1Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
KON90088.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
KON89995.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (422 aa)
KON89847.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
KON89836.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
KON89759.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
KON89758.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (431 aa)
hemL-2Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
KON89671.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (476 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (385 aa)
KON89324.1Aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
KON89295.1Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
KON89255.1Arginine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
KON88814.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
hisC-2Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (364 aa)
KON88625.12-amino-3-ketobutyrate CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
KON88426.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
KON88425.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
KON88412.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
rocDOrnithine--oxo-acid aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (399 aa)
KON86730.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
KON86735.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
KON86904.1Cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
gcvPBGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa)
hisCHistidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa)
KON90267.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
KON87503.1Aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
KON87534.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
KON87538.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
KON87735.1Serine-pyruvate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
KON87805.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
KON87830.1Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (462 aa)
KON87831.1Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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