STRINGSTRING
KON86906.1 KON86906.1 KON89833.1 KON89833.1 KON89807.1 KON89807.1 ppnK-2 ppnK-2 KON89404.1 KON89404.1 cobB cobB KON89271.1 KON89271.1 cinA cinA KON88749.1 KON88749.1 KON90366.1 KON90366.1 nadE nadE KON88441.1 KON88441.1 KON88033.1 KON88033.1 KON87939.1 KON87939.1 gabD gabD KON87927.1 KON87927.1 KON87923.1 KON87923.1 KON87808.1 KON87808.1 KON87769.1 KON87769.1 KON90299.1 KON90299.1 KON87594.1 KON87594.1 deoD deoD KON87163.1 KON87163.1 rsfS rsfS KON86971.1 KON86971.1 nadD nadD KON85692.1 KON85692.1 KON85866.1 KON85866.1 KON86180.1 KON86180.1 KON90195.1 KON90195.1 KON86535.1 KON86535.1 KON90232.1 KON90232.1 KON86707.1 KON86707.1 KON86740.1 KON86740.1 ppnK ppnK KON86905.1 KON86905.1 nadA nadA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KON86906.1Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (278 aa)
KON89833.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
KON89807.1Peptidase M29; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
ppnK-2Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (264 aa)
KON89404.1Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (619 aa)
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (239 aa)
KON89271.1Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
cinADamage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (416 aa)
KON88749.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
KON90366.1Prophage LambdaCh01 nuclease domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (273 aa)
KON88441.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (484 aa)
KON88033.1Ion transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
KON87939.1Dihydrouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
gabDSuccinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
KON87927.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
KON87923.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
KON87808.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
KON87769.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)
KON90299.1Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KON87594.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (60 aa)
deoDPurine nucleoside phosphorylase DeoD-type; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
KON87163.1Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa)
rsfSRibosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (118 aa)
KON86971.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (189 aa)
KON85692.1Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
KON85866.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
KON86180.1Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (926 aa)
KON90195.12', 3'-cyclic nucleotide 2'-phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (660 aa)
KON86535.1Ion transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
KON90232.1Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family. (365 aa)
KON86707.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
KON86740.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (266 aa)
KON86905.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (528 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (368 aa)
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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