STRINGSTRING
KON88457.1 KON88457.1 KON90103.1 KON90103.1 KON89997.1 KON89997.1 KON89905.1 KON89905.1 KON89867.1 KON89867.1 KON89866.1 KON89866.1 KON89767.1 KON89767.1 KON89760.1 KON89760.1 KON89642.1 KON89642.1 KON89641.1 KON89641.1 KON89583.1 KON89583.1 fumC fumC serC serC KON89509.1 KON89509.1 spxA-2 spxA-2 KON89380.1 KON89380.1 pdhA-2 pdhA-2 KON89265.1 KON89265.1 KON89264.1 KON89264.1 KON89263.1 KON89263.1 KON89236.1 KON89236.1 KON89202.1 KON89202.1 KON89201.1 KON89201.1 KON89200.1 KON89200.1 KON89138.1 KON89138.1 sucC sucC sucD sucD KON89013.1 KON89013.1 KON89012.1 KON89012.1 KON88999.1 KON88999.1 KON88888.1 KON88888.1 KON88783.1 KON88783.1 KON88767.1 KON88767.1 KON88765.1 KON88765.1 KON90370.1 KON90370.1 KON88663.1 KON88663.1 KON90367.1 KON90367.1 KON88648.1 KON88648.1 pdhA pdhA KON88637.1 KON88637.1 KON88636.1 KON88636.1 KON88635.1 KON88635.1 KON88626.1 KON88626.1 KON88618.1 KON88618.1 KON88582.1 KON88582.1 KON88549.1 KON88549.1 KON85459.1 KON85459.1 spxA spxA KON85588.1 KON85588.1 KON90167.1 KON90167.1 KON85690.1 KON85690.1 KON85704.1 KON85704.1 KON85732.1 KON85732.1 KON85833.1 KON85833.1 KON85851.1 KON85851.1 KON85861.1 KON85861.1 prs prs ldh ldh mqo mqo KON86000.1 KON86000.1 eutD eutD KON86077.1 KON86077.1 KON86078.1 KON86078.1 KON86080.1 KON86080.1 icmF icmF KON86087.1 KON86087.1 tal tal glpX glpX KON86106.1 KON86106.1 glyA glyA iolA iolA KON86223.1 KON86223.1 KON86381.1 KON86381.1 pgk pgk tpiA tpiA gpmI gpmI eno eno iolA-2 iolA-2 iolC iolC KON90206.1 KON90206.1 KON90208.1 KON90208.1 KON90209.1 KON90209.1 gcvH gcvH KON86524.1 KON86524.1 pgi pgi KON86605.1 KON86605.1 pckA pckA KON86689.1 KON86689.1 KON86719.1 KON86719.1 KON86739.1 KON86739.1 ackA ackA KON86766.1 KON86766.1 accD accD accA accA pfkA pfkA KON86771.1 KON86771.1 KON86775.1 KON86775.1 KON86776.1 KON86776.1 mdh mdh KON86778.1 KON86778.1 KON86787.1 KON86787.1 KON86823.1 KON86823.1 sdhA sdhA sdhB sdhB KON86833.1 KON86833.1 ldh-2 ldh-2 KON87055.1 KON87055.1 gcvT gcvT gcvPA gcvPA gcvPB gcvPB KON87097.1 KON87097.1 KON87098.1 KON87098.1 folD folD KON87116.1 KON87116.1 KON87120.1 KON87120.1 KON87121.1 KON87121.1 KON87129.1 KON87129.1 KON87130.1 KON87130.1 KON87134.1 KON87134.1 zwf zwf KON87136.1 KON87136.1 KON87150.1 KON87150.1 KON87195.1 KON87195.1 fhs fhs ilvA ilvA KON87532.1 KON87532.1 folD-2 folD-2 KON87645.1 KON87645.1 KON87646.1 KON87646.1 KON87668.1 KON87668.1 glcB glcB KON87735.1 KON87735.1 KON87761.1 KON87761.1 KON90300.1 KON90300.1 KON87825.1 KON87825.1 KON87830.1 KON87830.1 KON87831.1 KON87831.1 KON87885.1 KON87885.1 KON90314.1 KON90314.1 KON90316.1 KON90316.1 KON88005.1 KON88005.1 KON88039.1 KON88039.1 KON88068.1 KON88068.1 KON88218.1 KON88218.1 KON88223.1 KON88223.1 KON88280.1 KON88280.1 mdh-2 mdh-2 odhA odhA KON88430.1 KON88430.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KON88457.13-hydroxyacyl-ACP dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
KON90103.1Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
KON89997.1Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (331 aa)
KON89905.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
KON89867.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
KON89866.16-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
KON89767.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (517 aa)
KON89760.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
KON89642.1RpiR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
KON89641.16-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
KON89583.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (460 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)
KON89509.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
spxA-2ArsR family transcriptional regulator; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (131 aa)
KON89380.1RpiR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
pdhA-2Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)
KON89265.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
KON89264.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
KON89263.1Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
KON89236.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa)
KON89202.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
KON89201.1acetyl-CoA carboxylase; Composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
KON89200.1Carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
KON89138.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
KON89013.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
KON89012.12-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
KON88999.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
KON88888.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa)
KON88783.1Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
KON88767.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (549 aa)
KON88765.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
KON90370.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
KON88663.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (220 aa)
KON90367.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (291 aa)
KON88648.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
pdhAPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (356 aa)
KON88637.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
KON88636.1Dihydrolipoyllysine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
KON88635.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
KON88626.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (485 aa)
KON88618.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (902 aa)
KON88582.1Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
KON88549.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
KON85459.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
spxAArsR family transcriptional regulator; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (131 aa)
KON85588.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
KON90167.1Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
KON85690.1Antitoxin endoai; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
KON85704.1Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (206 aa)
KON85732.1Peptidase S66; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
KON85833.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
KON85851.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)
KON85861.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (309 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
KON86000.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
eutDPhosphotransacetylase; In Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
KON86077.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
KON86078.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
KON86080.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
icmFmethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1088 aa)
KON86087.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa)
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
KON86106.1Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
iolAMethylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. (486 aa)
KON86223.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
KON86381.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (394 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
iolA-2Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. (487 aa)
iolC5-dehydro-2-deoxygluconokinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP). (332 aa)
KON90206.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
KON90208.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (793 aa)
KON90209.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (119 aa)
gcvHGlycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (127 aa)
KON86524.1General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa)
KON86605.1Peptidase U35; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa)
KON86689.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
KON86719.1acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
KON86739.1acyl--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
KON86766.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
accDacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
KON86771.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
KON86775.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
KON86776.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
KON86778.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
KON86787.1Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (343 aa)
KON86823.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KON86833.1Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
ldh-2Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
KON87055.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (367 aa)
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
gcvPBGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa)
KON87097.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (168 aa)
KON87098.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
folD5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
KON87116.1Dihydrolipoamide dehydrogenase; E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
KON87120.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (617 aa)
KON87121.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (730 aa)
KON87129.1Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
KON87130.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
KON87134.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
KON87136.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
KON87150.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
KON87195.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (562 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa)
KON87532.1Peptidase S66; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
folD-25,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
KON87645.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (722 aa)
KON87646.1Electron transfer flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
KON87668.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (988 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)
KON87735.1Serine-pyruvate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
KON87761.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
KON90300.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (399 aa)
KON87825.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
KON87830.1Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (462 aa)
KON87831.1Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
KON87885.1ROK family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
KON90314.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
KON90316.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
KON88005.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (62 aa)
KON88039.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
KON88068.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
KON88218.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (359 aa)
KON88223.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
KON88280.1Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (217 aa)
mdh-2Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (318 aa)
odhA2-oxoglutarate dehydrogenase; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (947 aa)
KON88430.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
Your Current Organism:
Sporosarcina globispora
NCBI taxonomy Id: 1459
Other names: ATCC 23301, Bacillus globisporus, CCM 2119, CCUG 7419, CIP 103266, DSM 4, HAMBI 471, IFO 16082, JCM 10046, LMG 6928, LMG:6928, NBRC 16082, NCIMB 11434, NRRL B-3396, S. globispora, strain 785, strain W 25, strain W25
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