STRINGSTRING
NTE_00075 NTE_00075 NTE_00821 NTE_00821 NTE_01784 NTE_01784 NTE_01906 NTE_01906 trpD trpD trpA trpA trpB trpB NTE_01914 NTE_01914 NTE_02233 NTE_02233 NTE_03195 NTE_03195 hisD hisD hisB hisB hisH hisH hisA hisA hisF hisF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NTE_00075PFAM: Phosphoribosyl-AMP cyclohydrolase. (111 aa)
NTE_00821PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like. (220 aa)
NTE_01784PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: anthranilate synthase component I, archaeal clade. (453 aa)
NTE_01906Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (202 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (360 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
NTE_01914PFAM: Indole-3-glycerol phosphate synthase. (267 aa)
NTE_02233Phosphoserine phosphatase SerB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. (218 aa)
NTE_03195PFAM: HisG, C-terminal domain; ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, C-terminal domain; ATP phosphoribosyltransferase. (325 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (437 aa)
hisBPFAM: Imidazoleglycerol-phosphate dehydratase. (199 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (217 aa)
hisA1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (236 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (271 aa)
Your Current Organism:
Nitrososphaera evergladensis
NCBI taxonomy Id: 1459636
Other names: C. Nitrososphaera evergladensis SR1, Candidatus Nitrososphaera evergladensis SR1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.